aerpe-APE1547

Aeropyrum pernix 582aa long hypothetical acylamino-acid-releasing enzyme ApAAP

Comment

AARE Acyl-peptide hydrolase APH Acylaminoacyl-peptidase

Relationship

Family : ACPH_Peptidase_S9

Block : X

Position in NCBI Life Tree : Aeropyrum pernix

Molecular evidence

No mutation

No kinetic

No disease

Database

Sequence

Peptide

MRIIMPVEFS RIVRDVERLI AVEKYSLQGV VDGDKLLVVG FSEGSVNAYL YDGGETVKLN REPINSVLDP HYGVGRVILV RDVSKGAEQH ALFKVNTSRP GEEQRLEAVK PMRILSGVDT GEAVVFTGAT EDRVALYALD GGGLRELARL PGFGFVSDIR GDLIAGLGFF GGGRVSLFTS NLSSGGLRVF DSGEGSFSSA SISPGMKVTA GLETAREARL VTVDPRDGSV EDLELPSKDF SSYRPTAITW LGYLPDGRLA VVARREGRSA VFIDGERVEA PQGNHGRVVL WRGKLVTSHT SLSTPPRIVS LPSGEPLLEG GLPEDLRRSI AGSRLVWVES FDGSRVPTYV LESGRAPTPG PTVVLVHGGP FAEDSDSWDT FAASLAAAGF HVVMPNYRGS TGYGEEWRLK IIGDPCGGEL EDVSAAARWA RESGLASELY IMGYSYGGYM TLCALTMKPG LFKAGVAGAS VVDWEEMYEL SDAAFRNFIE QLTGGSREIM RSRSPINHVD RIKEPLALIH PQNDSRTPLK PLLRLMGELL ARGKTFEAHI IPDAGHAINT MEDAVKILLP AVFFLATQRE RR

References

Title : Understanding the interactions of different substrates with wild-type and mutant acylaminoacyl peptidase using molecular dynamics simulations - Zhu_2017_J.Biomol.Struct.Dyn__1
Author(s) : Zhu J , Wang Y , Li X , Han W , Zhao L
Ref : J Biomol Struct Dyn , :1 , 2017
Abstract : Zhu_2017_J.Biomol.Struct.Dyn__1
ESTHER : Zhu_2017_J.Biomol.Struct.Dyn__1
PubMedSearch : Zhu_2017_J.Biomol.Struct.Dyn__1
PubMedID: 29235404
Gene_locus related to this paper: aerpe-APE1547

Title : Exploration of the chlorpyrifos escape pathway from acylpeptide hydrolases using steered molecular dynamics simulations - Wang_2016_J.Biomol.Struct.Dyn_34_749
Author(s) : Wang D , Jin H , Wang J , Guan S , Zhang Z , Han W
Ref : J Biomol Struct Dyn , 34 :749 , 2016
Abstract : Wang_2016_J.Biomol.Struct.Dyn_34_749
ESTHER : Wang_2016_J.Biomol.Struct.Dyn_34_749
PubMedSearch : Wang_2016_J.Biomol.Struct.Dyn_34_749
PubMedID: 26155973
Gene_locus related to this paper: aerpe-APE1547

Title : Molecular dynamics simulations of acylpeptide hydrolase bound to chlorpyrifosmethyl oxon and dichlorvos - Jin_2015_Int.J.Mol.Sci_16_6217
Author(s) : Jin H , Zhou Z , Wang D , Guan S , Han W
Ref : Int J Mol Sci , 16 :6217 , 2015
Abstract : Jin_2015_Int.J.Mol.Sci_16_6217
ESTHER : Jin_2015_Int.J.Mol.Sci_16_6217
PubMedSearch : Jin_2015_Int.J.Mol.Sci_16_6217
PubMedID: 25794283
Gene_locus related to this paper: aerpe-APE1547

Title : Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality - Menyhard_2015_Acta.Crystallogr.D.Biol.Crystallogr_71_461
Author(s) : Menyhard DK , Orgovan Z , Szeltner Z , Szamosi I , Harmat V
Ref : Acta Crystallographica D Biol Crystallogr , 71 :461 , 2015
Abstract : Menyhard_2015_Acta.Crystallogr.D.Biol.Crystallogr_71_461
ESTHER : Menyhard_2015_Acta.Crystallogr.D.Biol.Crystallogr_71_461
PubMedSearch : Menyhard_2015_Acta.Crystallogr.D.Biol.Crystallogr_71_461
PubMedID: 25760596
Gene_locus related to this paper: aerpe-APE1547

Title : Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase - Harmat_2011_J.Biol.Chem_286_1987
Author(s) : Harmat V , Domokos K , Menyhard DK , Pallo A , Szeltner Z , Szamosi I , Beke-Somfai T , Naray-Szabo G , Polgar L
Ref : Journal of Biological Chemistry , 286 :1987 , 2011
Abstract : Harmat_2011_J.Biol.Chem_286_1987
ESTHER : Harmat_2011_J.Biol.Chem_286_1987
PubMedSearch : Harmat_2011_J.Biol.Chem_286_1987
PubMedID: 21084296
Gene_locus related to this paper: aerpe-APE1547

Title : Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase - Kiss_2008_J.Struct.Biol_162_312
Author(s) : Kiss AL , Pallo A , Naray-Szabo G , Harmat V , Polgar L
Ref : J Struct Biol , 162 :312 , 2008
Abstract : Kiss_2008_J.Struct.Biol_162_312
ESTHER : Kiss_2008_J.Struct.Biol_162_312
PubMedSearch : Kiss_2008_J.Struct.Biol_162_312
PubMedID: 18325786
Gene_locus related to this paper: aerpe-APE1547

Title : The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity - Kiss_2007_J.Mol.Biol_368_509
Author(s) : Kiss AL , Hornung B , Radi K , Gengeliczki Z , Sztaray B , Juhasz T , Szeltner Z , Harmat V , Polgar L
Ref : Journal of Molecular Biology , 368 :509 , 2007
Abstract : Kiss_2007_J.Mol.Biol_368_509
ESTHER : Kiss_2007_J.Mol.Biol_368_509
PubMedSearch : Kiss_2007_J.Mol.Biol_368_509
PubMedID: 17350041
Gene_locus related to this paper: aerpe-APE1547

Title : Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation - Wang_2006_J.Biol.Chem_281_18618
Author(s) : Wang Q , Yang G , Liu Y , Feng Y
Ref : Journal of Biological Chemistry , 281 :18618 , 2006
Abstract : Wang_2006_J.Biol.Chem_281_18618
ESTHER : Wang_2006_J.Biol.Chem_281_18618
PubMedSearch : Wang_2006_J.Biol.Chem_281_18618
PubMedID: 16670095
Gene_locus related to this paper: aerpe-APE1547

Title : Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase - Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
Author(s) : Wright H , Kiss AL , Szeltner Z , Polgar L , Fulop V
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 61 :942 , 2005
Abstract : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
ESTHER : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
PubMedSearch : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
PubMedID: 16511202
Gene_locus related to this paper: aerpe-APE1547

Title : Expression, purification and crystal structure of a truncated acylpeptide hydrolase from Aeropyrum pernix K1 - Zhang_2005_Acta.Biochim.Biophys.Sin.(Shanghai)_37_613
Author(s) : Zhang HF , Zheng BS , Peng Y , Lou ZY , Feng Y , Rao ZH
Ref : Acta Biochim Biophys Sin (Shanghai) , 37 :613 , 2005
Abstract : Zhang_2005_Acta.Biochim.Biophys.Sin.(Shanghai)_37_613
ESTHER : Zhang_2005_Acta.Biochim.Biophys.Sin.(Shanghai)_37_613
PubMedSearch : Zhang_2005_Acta.Biochim.Biophys.Sin.(Shanghai)_37_613
PubMedID: 16143816
Gene_locus related to this paper: aerpe-APE1547

Title : Crystal Structure of an Acylpeptide Hydrolase\/Esterase from Aeropyrum pernix K1. - Bartlam_2004_Structure.(Camb)_12_1481
Author(s) : Bartlam M , Wang G , Yang H , Gao R , Zhao X , Xie G , Cao S , Feng Y , Rao Z
Ref : Structure(Camb) , 12 :1481 , 2004
Abstract : Bartlam_2004_Structure.(Camb)_12_1481
ESTHER : Bartlam_2004_Structure.(Camb)_12_1481
PubMedSearch : Bartlam_2004_Structure.(Camb)_12_1481
PubMedID: 15296741
Gene_locus related to this paper: aerpe-APE1547

Title : Crystallization and preliminary crystallographic analysis of acylamino-acid releasing enzyme from the hyperthermophilic archaeon Aeropyrum pernix - Wang_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1054
Author(s) : Wang G , Gao R , Ding Y , Yang H , Cao S , Feng Y , Rao Z
Ref : Acta Crystallographica D Biol Crystallogr , 58 :1054 , 2002
Abstract : Wang_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1054
ESTHER : Wang_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1054
PubMedSearch : Wang_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1054
PubMedID: 12037315
Gene_locus related to this paper: aerpe-APE1547

Title : Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1 - Kawarabayasi_1999_DNA.Res_6_83
Author(s) : Kawarabayasi Y , Hino Y , Horikawa H , Yamazaki S , Haikawa Y , Jin-no K , Takahashi M , Sekine M , Baba S , Ankai A , Kosugi H , Hosoyama A , Fukui S , Nagai Y , Nishijima K , Nakazawa H , Takamiya M , Masuda S , Funahashi T , Tanaka T , Kudoh Y , Yamazaki J , Kushida N , Oguchi A , Aoki KI , Kubota K , Nakamura Y , Nomura N , Sako Y , Kikuchi H
Ref : DNA Research , 6 :83 , 1999
Abstract : Kawarabayasi_1999_DNA.Res_6_83
ESTHER : Kawarabayasi_1999_DNA.Res_6_83
PubMedSearch : Kawarabayasi_1999_DNA.Res_6_83
PubMedID: 10382966
Gene_locus related to this paper: aerpe-APE1244 , aerpe-APE1547 , aerpe-APE1832 , aerpe-APE2290 , aerpe-APE2361 , aerpe-APE2441