Gene_Locus Report

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Gene_locus Report for: 9zzzz-Axe1NaM1

Namib Desert hypoliths metagenome Acetyl-esterase deacetylase, hypolithon metagenome, Axe1NaM1

Relationship
Family|Acetyl-esterase_deacetylase
Block| X
Position in NCBI Life Tree|hypolithon metagenome
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> unclassified sequences: N E > metagenomes: N E > ecological metagenomes: N E > hypolithon metagenome: N E


Molecular evidence
Database
No mutation
1 structure:
6FKX: Namib Desert hypoliths metagenome Acetyl-esterase deacetylase
No kinetic





No Substrate
No inhibitor
2 Genbank : KX818842, ATB18054
1 Structure : 6FKX
Sequence
Graphical view for this peptide sequence: 9zzzz-Axe1NaM1
Colored MSA for Acetyl-esterase_deacetylase (raw)
VPLTFDLPFEELLTYPGRTPRPADHDEYWDRGLADLAAVPADVVIEPAEF
TTPLARCSHLWFTGTGGVRVHAKLLRPVAPVEPHPALLQFHGYTGNSGDW
SSRLHYVALGYTVAALDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAAD
NLALRHLFLDTARLAQIVLAMDDVDPDRVAATGYSQGGGLTLACAALEPR
IRLAAPVYPFLCDFRRAWEMDLEKGPYNEITTYFRARDPRHLREEEIFSR
LGYVDVQHLAPRVRAEVLMTVSLADKICPPSTQFAAYNKLGGPKDYRLYP
DFAHETLPGTDDAIFTFLQGL
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

VPLTFDLPFEELLTYPGRTPRPADHDEYWDRGLADLAAVPADVVIEPAEF
TTPLARCSHLWFTGTGGVRVHAKLLRPVAPVEPHPALLQFHGYTGNSGDW
SSRLHYVALGYTVAALDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAAD
NLALRHLFLDTARLAQIVLAMDDVDPDRVAATGYSQGGGLTLACAALEPR
IRLAAPVYPFLCDFRRAWEMDLEKGPYNEITTYFRARDPRHLREEEIFSR
LGYVDVQHLAPRVRAEVLMTVSLADKICPPSTQFAAYNKLGGPKDYRLYP
DFAHETLPGTDDAIFTFLQGL


Reference
    Title: Structural characterization and directed evolution of a novel acetyl xylan esterase reveals thermostability determinants of the Carbohydrate Esterase 7 family
    Adesioye FA, Makhalanyane TP, Vikram S, Sewell BT, Schubert WD, Cowan DA
    Ref: Applied Environmental Microbiology, 84:e02695, 2018 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
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