(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Eukaryota: NE > Viridiplantae: NE > Streptophyta: NE > Streptophytina: NE > Embryophyta: NE > Tracheophyta: NE > Euphyllophyta: NE > Spermatophyta: NE > Magnoliophyta: NE > Mesangiospermae: NE > eudicotyledons: NE > Gunneridae: NE > Pentapetalae: NE > asterids: NE > lamiids: NE > Lamiales: NE > Orobanchaceae: NE > Orobancheae: NE > Phelipanche: NE > Phelipanche aegyptiaca: NE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MSPLGDAHNVRVLGSGERTVVLSHGYGTDQSIWRQLVPHLVDDFRVVLYD NMGSGPTNPDYFDFERYATLEGYAHDLIAILMEFSFGKCIYVGHSLSAMA GLYASILRPDMFHKMIMLSATPRMLNEIDYHGGFEQKDLDQLLDMGIQNY KLLESGRAPLMIAGDMDSEVMQEFCRTLFNMRPDISLSLVHTMHTYDMRP FLKDVTVPCHIIQSSKDWAVPVKVSRYLQENIGAKSTVEVMSTEGHLPHL SAPEVTIPVLLRHIHHDIADA
Obligate parasitic plants in the Orobanchaceae germinate after sensing plant hormones, strigolactones, exuded from host roots. In Arabidopsis thaliana, the alpha/beta-hydrolase D14 acts as a strigolactone receptor that controls shoot branching, whereas its ancestral paralog, KAI2, mediates karrikin-specific germination responses. We observed that KAI2, but not D14, is present at higher copy numbers in parasitic species than in nonparasitic relatives. KAI2 paralogs in parasites are distributed into three phylogenetic clades. The fastest-evolving clade, KAI2d, contains the majority of KAI2 paralogs. Homology models predict that the ligand-binding pockets of KAI2d resemble D14. KAI2d transgenes confer strigolactone-specific germination responses to Arabidopsis thaliana. Thus, the KAI2 paralogs D14 and KAI2d underwent convergent evolution of strigolactone recognition, respectively enabling developmental responses to strigolactones in angiosperms and host detection in parasites.
