Homo sapiens (Human) Ccg1/TafII250-Interacting Factor B CIB MGC15429 Abhydrolase domain-containing protein 14B ABHD14B. lysine deacetylase
Alpha\/beta hydrolase domain-containing protein 14B. The general transcription initiation factor TFIID and its interactors play critical roles in regulating the transcription. TFIID interactor CCG1\/TAF(II)250-interacting factor B (CIB) activates transcription and has hydrolase activity towards p-nitrophenyl butyrate (in vitro). ABHD14B is able to transfer an acetyl group from a post-translationally acetylated-lysine to coenzyme A (CoA) and yield acetyl-CoA, while re-generating the free amine of protein lysine residues: lysine deacetylase (Rajendran et al. 2019)
MAASVEQREG TIQVQGQALF FREALPGSGQ ARFSVLLLHG IRFSSETWQN LGTLHRLAQA GYRAVAIDLP GLGHSKEAAA PAPIGELAPG SFLAAVVDAL ELGPPVVISP SLSGMYSLPF LTAPGSQLPG FVPVAPICTD KINAANYASV KTPALIVYGD QDPMGQTSFE HLKQLPNHRV LIMKGAGHPC YLDKPEEWHT GLLDFLQGLQ
Title : Identification of sequence determinants for the ABHD14 enzymes - Vaidya_2023_Proteins__ |
Author(s) : Vaidya K , Rodrigues G , Gupta S , Devarajan A , Yeolekar M , Madhusudhan MS , Kamat SS |
Ref : Proteins , : , 2023 |
Abstract : Vaidya_2023_Proteins__ |
ESTHER : Vaidya_2023_Proteins__ |
PubMedSearch : Vaidya_2023_Proteins__ |
PubMedID: 37974539 |
Gene_locus related to this paper: human-ABHD14A , human-CIB |
Title : In-depth Proteomic Signature of Parathyroid Carcinoma - Kong_2023_Eur.J.Endocrinol__ |
Author(s) : Kong SH , Lee JH , Bae JM , Hong N , Kim H , Park SY , Choi YJ , Lee S , Rhee Y , Kim SW , Han D , Kim JH , Shin CS |
Ref : European Journal of Endocrinology , : , 2023 |
Abstract : Kong_2023_Eur.J.Endocrinol__ |
ESTHER : Kong_2023_Eur.J.Endocrinol__ |
PubMedSearch : Kong_2023_Eur.J.Endocrinol__ |
PubMedID: 36995894 |
Gene_locus related to this paper: human-CIB |
Title : A multi-omics analysis reveals that the lysine deacetylase ABHD14B influences glucose metabolism in mammals - Rajendran_2022_J.Biol.Chem_298_102128 |
Author(s) : Rajendran A , Soory A , Khandelwal N , Ratnaparkhi G , Kamat SS |
Ref : Journal of Biological Chemistry , 298 :102128 , 2022 |
Abstract : Rajendran_2022_J.Biol.Chem_298_102128 |
ESTHER : Rajendran_2022_J.Biol.Chem_298_102128 |
PubMedSearch : Rajendran_2022_J.Biol.Chem_298_102128 |
PubMedID: 35700823 |
Gene_locus related to this paper: human-CIB |
Title : Functional Annotation of ABHD14B, an Orphan Serine Hydrolase Enzyme - Rajendran_2020_Biochemistry_59_183 |
Author(s) : Rajendran A , Vaidya K , Mendoza J , Bridwell-Rabb J , Kamat SS |
Ref : Biochemistry , 59 :183 , 2020 |
Abstract : Rajendran_2020_Biochemistry_59_183 |
ESTHER : Rajendran_2020_Biochemistry_59_183 |
PubMedSearch : Rajendran_2020_Biochemistry_59_183 |
PubMedID: 31478652 |
Gene_locus related to this paper: human-CIB |
Title : The crystal structure of CCG1\/TAF(II)250-interacting factor B (CIB) - Padmanabhan_2004_J.Biol.Chem_279_9615 |
Author(s) : Padmanabhan B , Kuzuhara T , Adachi N , Horikoshi M |
Ref : Journal of Biological Chemistry , 279 :9615 , 2004 |
Abstract : Padmanabhan_2004_J.Biol.Chem_279_9615 |
ESTHER : Padmanabhan_2004_J.Biol.Chem_279_9615 |
PubMedSearch : Padmanabhan_2004_J.Biol.Chem_279_9615 |
PubMedID: 14672934 |
Gene_locus related to this paper: human-CIB |
Title : Purification, crystallization and preliminary X-ray crystallographic analysis of human CCG1-interacting factor B - Padmanabhan_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1479 |
Author(s) : Padmanabhan B , Kuzuhara T , Mizuno H , Horikoshi M |
Ref : Acta Crystallographica D Biol Crystallogr , 56 :1479 , 2000 |
Abstract : Padmanabhan_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1479 |
ESTHER : Padmanabhan_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1479 |
PubMedSearch : Padmanabhan_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1479 |
PubMedID: 11053859 |
Gene_locus related to this paper: human-CIB |