Go to basket

Tree Display

AceDB Schema

XML Display


Family Report for: RsbQ-like


Family RsbQ-like
Block X
Parent Family : Abhydrolase_6

The RsbQ alpha/beta hydrolase and RsbP serine phosphatase form a signaling pair required to activate the general stress factor Sigma factor sigb of Bacillus subtilis in response to energy limitation. In plants RsbQ-like proteins could function downstream of strigolactone synthesis (Strigolactones are endogenous butenolide hormones that regulate shoot and root architecture, and stimulate the branching of arbuscular mycorrhizal fungi). DWARF14(D14) act as component of hormone signaling or as enzymes that participates in the conversion of strigolactones to the bioactive form. Karrikins (KARs) represent a family of butenolide compounds found in smoke that trigger the germination of many species after fire. KAI2 (karrikin-insensitive2) is required for normal seed germination and seedling growth. Conn et al. showed that convergent evolution of strigolactone perception enabled host detection in parasitic plants. Mutations in KAI2, encoding the proposed karrikin receptor, result in hypersensitivity to water deprivation.. The parasite Striga hermonthica is causing severe yield losses of cereals in sub-Saharan Africa. The germination of Striga seeds relies on host-released strigolactones (SLs) signaling molecules. SL analogs are developped as 'suicidal germination agents'(The induction of Striga seeds germination in the absence of the host leads to the death of germinating parasite). Wang et al. show that origins of strigolactone and karrikin signaling in plants could come from horizontal transfer from bacteria. The fungi D14 Fungal-D14-Strigolactone-R although homologous to family RsbQ-like of plant strigolactone receptors are somewhat far related and cannot supplement lack of receptor in arabidopsis for example. However Bacillus subtilis RsbQ is a functional butenolide hydrolase Melville et al.

IPR031143 (Strigolactone esterase D14 family D14_fam)
PF12697 (Abhydrolase_6)
no EC number

Peptide in
Nucleotide in
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
|Graphical display, obtained with the dnd file produced by Clustalw

30 more
    Title: Perception of butenolides by Bacillus subtilis via the alpha/beta hydrolase RsbQ
    Melville KT, Kamran M, Yao J, Costa M, Holland M, Taylor NL, Fritz G, Flematti GR, Waters MT
    Ref: Current Biology, :, 2023 : PubMed


    Title: KAI2 can do: Karrikin Receptor Function in Plant Development and Response to Abiotic and Biotic Factors
    Varshney K, Gutjahr C
    Ref: Plant Cell Physiol, :, 2023 : PubMed


    Title: Suicidal germination for parasitic weed control
    Zwanenburg B, Mwakaboko AS, Kannan C
    Ref: Pest Manag Sci, 72:2016, 2016 : PubMed


Other Papers

No structure scheme yet for this family

Structures in RsbQ-like family (66)

Genes Proteins in RsbQ-like family (207)

Fragments of genes in RsbQ-like family (8)

Substrates of some enzymes in the RsbQ-like family (44)

Inhibitors of some enzymes in the RsbQ-like family (35)

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer