MEST-like

Relationship

Family: MEST-like

Block: X

Parent Family: Epoxide-hydrolase_like

Comment

Mesoderm-specific transcript (Mest) predominantly expressed in mesoderm and its derivatives is also an imprinted gene whose expression is dependent on parental origin and is designated Peg1 (paternally expressed gene-1). Curiously orthologues seem present in vertebrates, few invertebrates (molluscs, ticks, amphioxus) but not in insects or nematodes. Absent in plants and present in a limited number of bacteria

Database

Interpro : No interpro

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (14)

Title : Mesoderm-specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy - Prudovsky_2018_J.Cell.Biochem_119_2636
Author(s) : Prudovsky I , Anunciado-Koza RP , Jacobs CG , Kacer D , Siviski ME , Koza RA
Ref : Journal of Cellular Biochemistry , 119 :2636 , 2018
Abstract : Prudovsky_2018_J.Cell.Biochem_119_2636
ESTHER : Prudovsky_2018_J.Cell.Biochem_119_2636
PubMedSearch : Prudovsky_2018_J.Cell.Biochem_119_2636
PubMedID: 29058774
Gene_locus related to this paper: mouse-MEST

Title : Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet - Anunciado-Koza_2016_Biochimie_124_134
Author(s) : Anunciado-Koza RP , Higgins DC , Koza RA
Ref : Biochimie , 124 :134 , 2016
Abstract : Anunciado-Koza_2016_Biochimie_124_134
ESTHER : Anunciado-Koza_2016_Biochimie_124_134
PubMedSearch : Anunciado-Koza_2016_Biochimie_124_134
PubMedID: 26005096
Gene_locus related to this paper: human-MEST , mouse-MEST

Title : Identification of Mest\/Peg1 gene expression as a predictive biomarker of adipose tissue expansion sensitive to dietary anti-obesity interventions - Voigt_2015_Genes.Nutr_10_477
Author(s) : Voigt A , Ribot J , Sabater AG , Palou A , Bonet ML , Klaus S
Ref : Genes Nutr , 10 :477 , 2015
Abstract : Voigt_2015_Genes.Nutr_10_477
ESTHER : Voigt_2015_Genes.Nutr_10_477
PubMedSearch : Voigt_2015_Genes.Nutr_10_477
PubMedID: 26143179

Title : Loss of inherited genomic imprints in mice leads to severe disruption in placental lipid metabolism - Himes_2015_Placenta_36_389
Author(s) : Himes KP , Young A , Koppes E , Stolz D , Barak Y , Sadovsky Y , Chaillet JR
Ref : Placenta , 36 :389 , 2015
Abstract : Himes_2015_Placenta_36_389
ESTHER : Himes_2015_Placenta_36_389
PubMedSearch : Himes_2015_Placenta_36_389
PubMedID: 25662615
Gene_locus related to this paper: human-MEST

Title : Variable imprinting of the MEST gene in human preimplantation embryos - Huntriss_2013_Eur.J.Hum.Genet_21_40
Author(s) : Huntriss JD , Hemmings KE , Hinkins M , Rutherford AJ , Sturmey RG , Elder K , Picton HM
Ref : Eur J Hum Genet , 21 :40 , 2013
Abstract : Huntriss_2013_Eur.J.Hum.Genet_21_40
ESTHER : Huntriss_2013_Eur.J.Hum.Genet_21_40
PubMedSearch : Huntriss_2013_Eur.J.Hum.Genet_21_40
PubMedID: 22763377
Gene_locus related to this paper: human-MEST

Title : Mest\/Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation - Jung_2011_Biochem.J_436_263
Author(s) : Jung H , Lee SK , Jho EH
Ref : Biochemical Journal , 436 :263 , 2011
Abstract : Jung_2011_Biochem.J_436_263
ESTHER : Jung_2011_Biochem.J_436_263
PubMedSearch : Jung_2011_Biochem.J_436_263
PubMedID: 21375506
Gene_locus related to this paper: human-MEST

Title : Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance - Nikonova_2008_FASEB.J_22_3925
Author(s) : Nikonova L , Koza RA , Mendoza T , Chao PM , Curley JP , Kozak LP
Ref : FASEB Journal , 22 :3925 , 2008
Abstract : Nikonova_2008_FASEB.J_22_3925
ESTHER : Nikonova_2008_FASEB.J_22_3925
PubMedSearch : Nikonova_2008_FASEB.J_22_3925
PubMedID: 18644838
Gene_locus related to this paper: human-MEST , mouse-MEST

Title : Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32 - Nakabayashi_2002_Hum.Mol.Genet_11_1743
Author(s) : Nakabayashi K , Bentley L , Hitchins MP , Mitsuya K , Meguro M , Minagawa S , Bamforth JS , Stanier P , Preece M , Weksberg R , Oshimura M , Moore GE , Scherer SW
Ref : Hum Mol Genet , 11 :1743 , 2002
Abstract : Nakabayashi_2002_Hum.Mol.Genet_11_1743
ESTHER : Nakabayashi_2002_Hum.Mol.Genet_11_1743
PubMedSearch : Nakabayashi_2002_Hum.Mol.Genet_11_1743
PubMedID: 12095916
Gene_locus related to this paper: mouse-MEST

Title : Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest - Lefebvre_1998_Nat.Genet_20_163
Author(s) : Lefebvre L , Viville S , Barton SC , Ishino F , Keverne EB , Surani MA
Ref : Nat Genet , 20 :163 , 1998
Abstract : Lefebvre_1998_Nat.Genet_20_163
ESTHER : Lefebvre_1998_Nat.Genet_20_163
PubMedSearch : Lefebvre_1998_Nat.Genet_20_163
PubMedID: 9771709
Gene_locus related to this paper: human-MEST , mouse-MEST

Title : Monoallelic expression of human PEG1\/MEST is paralleled by parent-specific methylation in fetuses - Riesewijk_1997_Genomics_42_236
Author(s) : Riesewijk AM , Hu L , Schulz U , Tariverdian G , Hoglund P , Kere J , Ropers HH , Kalscheuer VM
Ref : Genomics , 42 :236 , 1997
Abstract : Riesewijk_1997_Genomics_42_236
ESTHER : Riesewijk_1997_Genomics_42_236
PubMedSearch : Riesewijk_1997_Genomics_42_236
PubMedID: 9192843
Gene_locus related to this paper: human-MEST

Title : Genomic structure and parent-of-origin-specific methylation of Peg1 - Lefebvre_1997_Hum.Mol.Genet_6_1907
Author(s) : Lefebvre L , Viville S , Barton SC , Ishino F , Surani MA
Ref : Hum Mol Genet , 6 :1907 , 1997
Abstract : Lefebvre_1997_Hum.Mol.Genet_6_1907
ESTHER : Lefebvre_1997_Hum.Mol.Genet_6_1907
PubMedSearch : Lefebvre_1997_Hum.Mol.Genet_6_1907
PubMedID: 9302270
Gene_locus related to this paper: human-MEST , mouse-MEST

Title : Genomic imprinting and chromosomal localization of the human MEST gene - Nishita_1996_Genomics_36_539
Author(s) : Nishita Y , Yoshida I , Sado T , Takagi N
Ref : Genomics , 36 :539 , 1996
Abstract : Nishita_1996_Genomics_36_539
ESTHER : Nishita_1996_Genomics_36_539
PubMedSearch : Nishita_1996_Genomics_36_539
PubMedID: 8884280
Gene_locus related to this paper: human-MEST

Title : Peg1\/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization - Kaneko-Ishino_1995_Nat.Genet_11_52
Author(s) : Kaneko-Ishino T , Kuroiwa Y , Miyoshi N , Kohda T , Suzuki R , Yokoyama M , Viville S , Barton SC , Ishino F , Surani MA
Ref : Nat Genet , 11 :52 , 1995
Abstract : Kaneko-Ishino_1995_Nat.Genet_11_52
ESTHER : Kaneko-Ishino_1995_Nat.Genet_11_52
PubMedSearch : Kaneko-Ishino_1995_Nat.Genet_11_52
PubMedID: 7550314
Gene_locus related to this paper: mouse-MEST

Title : A novel mesoderm-specific cDNA isolated from a mouse embryonal carcinoma cell line -
Author(s) : Sado T , Nakajima N , Tada M , Takagi N
Ref : Dev Growth Differ , 35 :551 , 1993
PubMedID:
Gene_locus related to this paper: human-MEST , mouse-MEST

No structure scheme yet for this family

Genes Proteins in MEST-like family (58)

Fragments of genes in MEST-like family (2)

No fragment of genes

No substrate

No Inhibitor