Interpro : IPR026605 Monoacylglycerol lipase protein ABHD12
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
Title : Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs - Khandelwal_2021_Cell.Chem.Biol__ |
Author(s) : Khandelwal N , Shaikh M , Mhetre A , Singh S , Sajeevan T , Joshi A , Balaji KN , Chakrapani H , Kamat SS |
Ref : Cell Chemical Biology , : , 2021 |
Abstract : Khandelwal_2021_Cell.Chem.Biol__ |
ESTHER : Khandelwal_2021_Cell.Chem.Biol__ |
PubMedSearch : Khandelwal_2021_Cell.Chem.Biol__ |
PubMedID: 33571455 |
Gene_locus related to this paper: human-ABHD12 |
Title : Mapping the neuroanatomy of ABHD16A-ABHD12 & lysophosphatidylserines provides new insights into the pathophysiology of the human neurological disorder PHARC - Singh_2020_Biochemistry_59_2299 |
Author(s) : Singh S , Joshi A , Kamat SS |
Ref : Biochemistry , 59 :2299 , 2020 |
Abstract : Singh_2020_Biochemistry_59_2299 |
ESTHER : Singh_2020_Biochemistry_59_2299 |
PubMedSearch : Singh_2020_Biochemistry_59_2299 |
PubMedID: 32462874 |
Gene_locus related to this paper: human-ABHD12 , human-ABHD16A |
Title : A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase - Kelkar_2019_Nat.Chem.Biol_15_169 |
Author(s) : Kelkar DS , Ravikumar G , Mehendale N , Singh S , Joshi A , Sharma AK , Mhetre A , Rajendran A , Chakrapani H , Kamat SS |
Ref : Nat Chemical Biology , 15 :169 , 2019 |
Abstract : Kelkar_2019_Nat.Chem.Biol_15_169 |
ESTHER : Kelkar_2019_Nat.Chem.Biol_15_169 |
PubMedSearch : Kelkar_2019_Nat.Chem.Biol_15_169 |
PubMedID: 30643283 |
Gene_locus related to this paper: human-ABHD12 |
Title : Biochemical characterization of the PHARC-associated serine hydrolase ABHD12 reveals its preference for very-long-chain lipids - Joshi_2018_J.Biol.Chem_293_16953 |
Author(s) : Joshi A , Shaikh M , Singh S , Rajendran A , Mhetre A , Kamat SS |
Ref : Journal of Biological Chemistry , 293 :16953 , 2018 |
Abstract : Joshi_2018_J.Biol.Chem_293_16953 |
ESTHER : Joshi_2018_J.Biol.Chem_293_16953 |
PubMedSearch : Joshi_2018_J.Biol.Chem_293_16953 |
PubMedID: 30237167 |
Gene_locus related to this paper: human-ABHD12 |
Title : Structural properties and role of the endocannabinoid lipases ABHD6 and ABHD12 in lipid signalling and disease - Kind_2019_Amino.Acids_51_151 |
Author(s) : Kind L , Kursula P |
Ref : Amino Acids , 51 :151 , 2018 |
Abstract : Kind_2019_Amino.Acids_51_151 |
ESTHER : Kind_2019_Amino.Acids_51_151 |
PubMedSearch : Kind_2019_Amino.Acids_51_151 |
PubMedID: 30564946 |
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 |
Title : Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay - Kamat_2015_Nat.Chem.Biol_11_164 |
Author(s) : Kamat SS , Camara K , Parsons WH , Chen DH , Dix MM , Bird TD , Howell AR , Cravatt BF |
Ref : Nat Chemical Biology , 11 :164 , 2015 |
Abstract : Kamat_2015_Nat.Chem.Biol_11_164 |
ESTHER : Kamat_2015_Nat.Chem.Biol_11_164 |
PubMedSearch : Kamat_2015_Nat.Chem.Biol_11_164 |
PubMedID: 25580854 |
Gene_locus related to this paper: human-ABHD12 , human-ABHD16A , mouse-abd12 , mouse-Abhd16a |
Title : ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC - Blankman_2013_Proc.Natl.Acad.Sci.U.S.A_110_1500 |
Author(s) : Blankman JL , Long JZ , Trauger SA , Siuzdak G , Cravatt BF |
Ref : Proc Natl Acad Sci U S A , 110 :1500 , 2013 |
Abstract : Blankman_2013_Proc.Natl.Acad.Sci.U.S.A_110_1500 |
ESTHER : Blankman_2013_Proc.Natl.Acad.Sci.U.S.A_110_1500 |
PubMedSearch : Blankman_2013_Proc.Natl.Acad.Sci.U.S.A_110_1500 |
PubMedID: 23297193 |
Title : Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism - Fiskerstrand_2010_Am.J.Hum.Genet_87_410 |
Author(s) : Fiskerstrand T , H'Mida-Ben Brahim D , Johansson S , M'Zahem A , Haukanes BI , Drouot N , Zimmermann J , Cole AJ , Vedeler C , Bredrup C , Assoum M , Tazir M , Klockgether T , Hamri A , Steen VM , Boman H , Bindoff LA , Koenig M , Knappskog PM |
Ref : American Journal of Human Genetics , 87 :410 , 2010 |
Abstract : Fiskerstrand_2010_Am.J.Hum.Genet_87_410 |
ESTHER : Fiskerstrand_2010_Am.J.Hum.Genet_87_410 |
PubMedSearch : Fiskerstrand_2010_Am.J.Hum.Genet_87_410 |
PubMedID: 20797687 |
Gene_locus related to this paper: human-ABHD12 |
Title : A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol - Blankman_2007_Chem.Biol_14_1347 |
Author(s) : Blankman JL , Simon GM , Cravatt BF |
Ref : Chemical Biology , 14 :1347 , 2007 |
Abstract : Blankman_2007_Chem.Biol_14_1347 |
ESTHER : Blankman_2007_Chem.Biol_14_1347 |
PubMedSearch : Blankman_2007_Chem.Biol_14_1347 |
PubMedID: 18096503 |
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
No structure scheme yet for this family
Genes Proteins in ABHD12-PHARC family (197)
Fragments of genes in ABHD12-PHARC family (42)
No fragment of genesSubstrates in ABHD12-PHARC family (4)
Inhibitors in ABHD12-PHARC family (5)