Proline_iminopeptidase
Relationship
Comment
This entry describes a subfamily of the alpha/beta fold family. This entry represents a of serine peptidase belonging to peptidase family S33 (clan SC). Family members include prolinases (Pro-Xaa dipeptidase, EC:3.4.13.18), prolyl aminopeptidases (EC:3.4.11.5), and a leucyl aminopeptidase. Prolyl aminopeptidase Pro_amnoPtase (S33 family) PROAMNOPTASE Pept_S33_TRI_F1 Pro_imino_pep_2. (Crystal structure of the proline iminopeptidase-related protein TTHA1809 from Thermus thermophilus HB8 (2YYS) showed that it lacks the active site serine and probably similar proteins play non enzymatic role in a few bacteria: Okai et al.2008)Database
Interpro : IPR005945 Peptidase S33, Proline-specific peptidase , IPR005944 Peptidase S33, Proline iminopeptidase , IPR002410 Peptidase S33 , IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Pept_S33_TAP-like_C
PIRSF : PIRSF005539 proline-specific peptidase, F1 type , PIRSF006431 Pept_S33
Pdoc : No Pdoc
Pfam : PF12697 Abhydrolase_6
Prints : PR00793
EC Number : 3.4.11.5
References (9)
| Title : Crystal structure of the proline iminopeptidase-related protein TTHA1809 from Thermus thermophilus HB8 - Okada_2008_J.Food.Sci_73_C146 |
| Author(s) : Okai M , Miyauchi Y , Ebihara A , Lee WC , Nagata K , Tanokura M |
| Ref : Proteins , 70 :1646 , 2008 |
| Abstract : Okada_2008_J.Food.Sci_73_C146 |
| ESTHER : Okada_2008_J.Food.Sci_73_C146 |
| PubMedSearch : Okada_2008_J.Food.Sci_73_C146 |
| PubMedID: 18175319 |
| Gene_locus related to this paper: thet2-q72hm9 |
| Title : Unusual extra space at the active site and high activity for acetylated hydroxyproline of prolyl aminopeptidase from Serratia marcescens - Nakajima_2006_J.Bacteriol_188_1599 |
| Author(s) : Nakajima Y , Ito K , Sakata M , Xu Y , Nakashima K , Matsubara F , Hatakeyama S , Yoshimoto T |
| Ref : Journal of Bacteriology , 188 :1599 , 2006 |
| Abstract : Nakajima_2006_J.Bacteriol_188_1599 |
| ESTHER : Nakajima_2006_J.Bacteriol_188_1599 |
| PubMedSearch : Nakajima_2006_J.Bacteriol_188_1599 |
| PubMedID: 16452443 |
| Gene_locus related to this paper: serma-impep |
| Title : X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum - Goettig_2005_J.Biol.Chem_280_33387 |
| Author(s) : Goettig P , Brandstetter H , Groll M , Gohring W , Konarev PV , Svergun DI , Huber R , Kim JS |
| Ref : Journal of Biological Chemistry , 280 :33387 , 2005 |
| Abstract : Goettig_2005_J.Biol.Chem_280_33387 |
| ESTHER : Goettig_2005_J.Biol.Chem_280_33387 |
| PubMedSearch : Goettig_2005_J.Biol.Chem_280_33387 |
| PubMedID: 15994304 |
| Gene_locus related to this paper: theac-pip |
| Title : Molecular and genetic characterization of propionicin F, a bacteriocin from Propionibacterium freudenreichii - Brede_2004_Appl.Environ.Microbiol_70_7303 |
| Author(s) : Brede DA , Faye T , Johnsborg O , Odegard I , Nes IF , Holo H |
| Ref : Applied Environmental Microbiology , 70 :7303 , 2004 |
| Abstract : Brede_2004_Appl.Environ.Microbiol_70_7303 |
| ESTHER : Brede_2004_Appl.Environ.Microbiol_70_7303 |
| PubMedSearch : Brede_2004_Appl.Environ.Microbiol_70_7303 |
| PubMedID: 15574930 |
| Gene_locus related to this paper: 9acto-q6e3k7 |
| Title : Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor - Inoue_2003_Arch.Biochem.Biophys_416_147 |
| Author(s) : Inoue T , Ito K , Tozaka T , Hatakeyama S , Tanaka N , Nakamura KT , Yoshimoto T |
| Ref : Archives of Biochemistry & Biophysics , 416 :147 , 2003 |
| Abstract : Inoue_2003_Arch.Biochem.Biophys_416_147 |
| ESTHER : Inoue_2003_Arch.Biochem.Biophys_416_147 |
| PubMedSearch : Inoue_2003_Arch.Biochem.Biophys_416_147 |
| PubMedID: 12893291 |
| Gene_locus related to this paper: serma-impep |
| Title : Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism - Goettig_2002_Embo.J_21_5343 |
| Author(s) : Goettig P , Groll M , Kim JS , Huber R , Brandstetter H |
| Ref : EMBO Journal , 21 :5343 , 2002 |
| Abstract : Goettig_2002_Embo.J_21_5343 |
| ESTHER : Goettig_2002_Embo.J_21_5343 |
| PubMedSearch : Goettig_2002_Embo.J_21_5343 |
| PubMedID: 12374735 |
| Gene_locus related to this paper: theac-pip |
| Title : Crystal structure of prolyl aminopeptidase from Serratia marcescens - Yoshimoto_1999_J.Biochem_126_559 |
| Author(s) : Yoshimoto T , Kabashima T , Uchikawa K , Inoue T , Tanaka N , Nakamura KT , Tsuru M , Ito K |
| Ref : J Biochem , 126 :559 , 1999 |
| Abstract : Yoshimoto_1999_J.Biochem_126_559 |
| ESTHER : Yoshimoto_1999_J.Biochem_126_559 |
| PubMedSearch : Yoshimoto_1999_J.Biochem_126_559 |
| PubMedID: 10467172 |
| Gene_locus related to this paper: serma-impep |
| Title : Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family - Medrano_1998_EMBO.J_17_1 |
| Author(s) : Medrano FJ , Alonso J , Garcia JL , Romero A , Bode W , Gomis-Ruth FX |
| Ref : EMBO Journal , 17 :1 , 1998 |
| Abstract : Medrano_1998_EMBO.J_17_1 |
| ESTHER : Medrano_1998_EMBO.J_17_1 |
| PubMedSearch : Medrano_1998_EMBO.J_17_1 |
| PubMedID: 9427736 |
| Gene_locus related to this paper: xanca-impep |
| Title : Tricorn protease (TRI) interacting factor 1 from Thermoplasma acidophilum is a proline iminopeptidase - Tamura_1996_FEBS.Lett_398_101 |
| Author(s) : Tamura T , Tamura N , Lottspeich F , Baumeister W |
| Ref : FEBS Letters , 398 :101 , 1996 |
| Abstract : Tamura_1996_FEBS.Lett_398_101 |
| ESTHER : Tamura_1996_FEBS.Lett_398_101 |
| PubMedSearch : Tamura_1996_FEBS.Lett_398_101 |
| PubMedID: 8946961 |
| Gene_locus related to this paper: theac-pip |
Structures (24)
Genes Proteins in Proline_iminopeptidase family (1003)
Fragments of genes in Proline_iminopeptidase family (36)
Structures in Proline_iminopeptidase family (24)Substrates in Proline_iminopeptidase family (10)
Inhibitors in Proline_iminopeptidase family (4)