1. Home
  2. Family
  3. Peptidase_S15

Peptidase_S15

Relationship

Family: Peptidase_S15

Block: X

Parent Family: No family

Comment

This entry represents a domain found peptidases Xaa-Pro dipeptidyl-peptidase and glutaryl-7-aminocephalosporanic-acid acylase, which belong to MEROPS peptidase families S15. It is also found in hydrolases from the CocE/NonD family. Cocaine esterase (CocE) hydrolyzes cocaine endowing the bacteria with the ability to utilise cocaine as a sole source of carbon and energy. YcjY-like are bacterial cell division gene and LipSM54-like_FamXVI belongs also to this larger family

Database

Interpro : IPR000383 X-Pro dipeptidyl-peptidase-like domain Peptidase_S15 , IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal Xaa-Pro_dipept_C

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF02129 Peptidase_S15 , PF08530 PepX_C

Prints : No Print

EC Number : 3.4.14.11

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (3)

Title : Crystal structure of a bacterial cocaine esterase -
Author(s) : Larsen NA , Turner JM , Stevens J , Rosser SJ , Basran A , Lerner RA , Bruce NC , Wilson IA
Ref : Nat Struct Biol , 9 :17 , 2002
PubMedID: 11742345
Gene_locus related to this paper: rhosm-cocE

Title : The Structural Basis for Catalysis and Specificity of the X-Prolyl Dipeptidyl Aminopeptidase from Lactococcus lactis - Rigolet_2002_Structure.(Camb)_10_1383
Author(s) : Rigolet P , Mechin I , Delage M , Chich J
Ref : Structure (Camb) , 10 :1383 , 2002
Abstract : Rigolet_2002_Structure.(Camb)_10_1383
ESTHER : Rigolet_2002_Structure.(Camb)_10_1383
PubMedSearch : Rigolet_2002_Structure.(Camb)_10_1383
PubMedID: 12377124
Gene_locus related to this paper: lacla-pepx

Title : Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1 - Bresler_2000_Appl.Environ.Microbiol_66_904
Author(s) : Bresler MM , Rosser SJ , Basran A , Bruce NC
Ref : Applied Environmental Microbiology , 66 :904 , 2000
Abstract : Bresler_2000_Appl.Environ.Microbiol_66_904
ESTHER : Bresler_2000_Appl.Environ.Microbiol_66_904
PubMedSearch : Bresler_2000_Appl.Environ.Microbiol_66_904
PubMedID: 10698749
Gene_locus related to this paper: rhosm-cocE

No structure scheme yet for this family

No Genes Proteins

No fragment of genes

No fragment of genes

Substrates in Peptidase_S15 family (1)

Inhibitors in Peptidase_S15 family (3)