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Family Report for: Lipase_bact_N_lipase


Block X
This family has the N-terminal region of bacterial virulence factor lipase. The N-terminal region contains a potential signalling sequence. Most proteins with this N-terminal sequence have a typical alpha/beta hydrolase following in c-term. The N-terminal region is found also in proteins without lipase or alpha/beta hydrolases. The N-term domain is used to populate the family but is excluded here. Chuang et al. on aerhy-LIP found hydrolysis of p-nitrophenyl esters (optimum C10-C12) and triacylglycerols (optimum C8- C10)

IPR025920 (Bacterial virulence factor lipase N-terminal domain), IPR020009 (Extracellular lipase, Pla-1/cef family Extracell_lipase_Pla-1/cef_e)
PF12262 (Lipase_bact_N)
no EC number

Peptide in
Nucleotide in
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
|Graphical display, obtained with the dnd file produced by Clustalw

1 more
    Title: Cloning, sequencing, and role in virulence of two phospholipases (A1 and C) from mesophilic Aeromonas sp. serogroup O:34
    Merino S, Aguilar A, Nogueras MM, Regue M, Swift S, Tomas JM
    Ref: Infect Immun, 67:4008, 1999 : PubMed


    Title: Molecular analysis and expression of the extracellular lipase of Aeromonas hydrophila MCC-2
    Chuang YC, Chiou SF, Su JH, Wu ML, Chang MC
    Ref: Microbiology, 143 ( Pt 3):803, 1997 : PubMed


    Title: Purification, gene cloning, amino acid sequence analysis, and expression of an extracellular lipase from an Aeromonas hydrophila human isolate
    Anguita J, Rodriguez Aparicio LB, Naharro G
    Ref: Applied Environmental Microbiology, 59:2411, 1993 : PubMed


Other Papers

No structure scheme yet for this family

No Structure yet in this family

Genes Proteins in Lipase_bact_N_lipase family (10)

No fragments
Substrates of some enzymes in the Lipase_bact_N_lipase family (3)

No Inhibitor

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
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AcePerl Lincoln Stein Home Page

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