Acetyl-esterase_deacetylase
Relationship
Comment
PF05448 AXE1 Acetyl xylan esterase (EC 3.1.1.72) and cephalosporin c deacetylase (EC 3.1.1.41). This domain can be found in several bacterial acetyl xylan esterase proteins. Acetyl xylan esterases are enzymes that hydrolyse the ester linkages of the acetyl groups in position 2 and/or 3 of the xylose moieties of natural acetylated xylan from hardwood. These enzymes are one of the accessory enzymes which are part of the xylanolytic system, together with xylanases, beta-xylosidases, alpha-arabinofuranosidases and methylglucuronidases; these are all required for the complete hydrolysis of xylan Some sequences were previously in the Bacterial_lipase family (thema-TM0077...). Members of the family were associated with IPR000734, the esterase and lipase active site serine. This family contains the carbohydrate esterase family seven (CE-7) see the CAZy (Carbohydrate-Active enZYmes server ) (CE_7)Database
Interpro : IPR008391 AXE1_dom , IPR039069 Carbohydrate esterase 7 family CE7
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF05448 AXE1
Prints : No Print
EC Number : 3.1.1.72 || 3.1.1.41
References (6)
| Title : Crystal structure and functional characterization of a cold-active acetyl xylan esterase (PbAcE) from psychrophilic soil microbe Paenibacillus sp - Park_2018_PLoS.One_13_e0206260 |
| Author(s) : Park SH , Yoo W , Lee CW , Jeong CS , Shin SC , Kim HW , Park H , Kim KK , Kim TD , Lee JH |
| Ref : PLoS ONE , 13 :e0206260 , 2018 |
| Abstract : Park_2018_PLoS.One_13_e0206260 |
| ESTHER : Park_2018_PLoS.One_13_e0206260 |
| PubMedSearch : Park_2018_PLoS.One_13_e0206260 |
| PubMedID: 30379876 |
| Gene_locus related to this paper: 9mico-6AGQ |
| Title : Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima - Levisson_2012_Proteins_80_1545 |
| Author(s) : Levisson M , Han GW , Deller MC , Xu Q , Biely P , Hendriks S , Ten Eyck LF , Flensburg C , Roversi P , Miller MD , McMullan D , von Delft F , Kreusch A , Deacon AM , Van der Oost J , Lesley SA , Elsliger MA , Kengen SW , Wilson IA |
| Ref : Proteins , 80 :1545 , 2012 |
| Abstract : Levisson_2012_Proteins_80_1545 |
| ESTHER : Levisson_2012_Proteins_80_1545 |
| PubMedSearch : Levisson_2012_Proteins_80_1545 |
| PubMedID: 22411095 |
| Gene_locus related to this paper: thema-TM0077 |
| Title : The crystal structure of the cephalosporin deacetylating enzyme acetyl xylan esterase bound to paraoxon explains the low sensitivity of this serine hydrolase to organophosphate inactivation - Montoro-Garcia_2011_Biochem.J_436_321 |
| Author(s) : Montoro-Garcia S , Gil-Ortiz F , Garcia-Carmona F , Polo LM , Rubio V , Sanchez-Ferrer A |
| Ref : Biochemical Journal , 436 :321 , 2011 |
| Abstract : Montoro-Garcia_2011_Biochem.J_436_321 |
| ESTHER : Montoro-Garcia_2011_Biochem.J_436_321 |
| PubMedSearch : Montoro-Garcia_2011_Biochem.J_436_321 |
| PubMedID: 21382014 |
| Gene_locus related to this paper: bacpu-AXE |
| Title : Biochemical characterization and relative expression levels of multiple carbohydrate esterases of the xylanolytic rumen bacterium Prevotella ruminicola 23 grown on an ester-enriched substrate - Kabel_2011_Appl.Environ.Microbiol_77_5671 |
| Author(s) : Kabel MA , Yeoman CJ , Han Y , Dodd D , Abbas CA , de Bont JA , Morrison M , Cann IK , Mackie RI |
| Ref : Applied Environmental Microbiology , 77 :5671 , 2011 |
| Abstract : Kabel_2011_Appl.Environ.Microbiol_77_5671 |
| ESTHER : Kabel_2011_Appl.Environ.Microbiol_77_5671 |
| PubMedSearch : Kabel_2011_Appl.Environ.Microbiol_77_5671 |
| PubMedID: 21742923 |
| Gene_locus related to this paper: prer2-axea1 , prer2-axfa |
| Title : Multifunctional Xylooligosaccharide\/Cephalosporin C Deacetylase Revealed by the Hexameric Structure of the Bacillus subtilis Enzyme at 1.9A Resolution - Vincent_2003_J.Mol.Biol_330_593 |
| Author(s) : Vincent F , Charnock SJ , Verschueren KH , Turkenburg JP , Scott DJ , Offen WA , Roberts S , Pell G , Gilbert HJ , Davies GJ , Brannigan JA |
| Ref : Journal of Molecular Biology , 330 :593 , 2003 |
| Abstract : Vincent_2003_J.Mol.Biol_330_593 |
| ESTHER : Vincent_2003_J.Mol.Biol_330_593 |
| PubMedSearch : Vincent_2003_J.Mol.Biol_330_593 |
| PubMedID: 12842474 |
| Gene_locus related to this paper: bacsu-CAH |
| Title : The acetyl xylan esterase of Bacillus pumilus belongs to a family of esterases with broad substrate specificity - Degrassi_2000_Microbiology_146 ( Pt 7)_1585 |
| Author(s) : Degrassi G , Kojic M , Ljubijankic G , Venturi V |
| Ref : Microbiology , 146 ( Pt 7) :1585 , 2000 |
| Abstract : Degrassi_2000_Microbiology_146 ( Pt 7)_1585 |
| ESTHER : Degrassi_2000_Microbiology_146 ( Pt 7)_1585 |
| PubMedSearch : Degrassi_2000_Microbiology_146 ( Pt 7)_1585 |
| PubMedID: 10878123 |
| Gene_locus related to this paper: bacpu-AXE |
Structures (21)
Genes Proteins in Acetyl-esterase_deacetylase family (291)
Fragments of genes in Acetyl-esterase_deacetylase family (11)
Structures in Acetyl-esterase_deacetylase family (21)Substrates in Acetyl-esterase_deacetylase family (9)
Inhibitors in Acetyl-esterase_deacetylase family (2)