Interpro : No interpro
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
Title : ABHD6 drives endocytosis of AMPA receptors to regulate synaptic plasticity and learning flexibility - Wei_2023_Prog.Neurobiol__102559 |
Author(s) : Wei M , Yang L , Su F , Liu Y , Zhao X , Luo L , Sun X , Liu S , Dong Z , Zhang Y , Shi YS , Liang J , Zhang C |
Ref : Prog Neurobiol , :102559 , 2023 |
Abstract : Wei_2023_Prog.Neurobiol__102559 |
ESTHER : Wei_2023_Prog.Neurobiol__102559 |
PubMedSearch : Wei_2023_Prog.Neurobiol__102559 |
PubMedID: 38159878 |
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
Title : ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol\/PPAR signaling in obese mice - Poursharifi_2023_Mol.Metab__101822 |
Author(s) : Poursharifi P , Schmitt C , Chenier I , Leung YH , Oppong AK , Bai Y , Klein LL , Al-Mass A , Lussier R , Abu-Farha M , Abubaker J , Al-Mulla F , Peyot ML , Madiraju SRM , Prentki M |
Ref : Mol Metab , :101822 , 2023 |
Abstract : Poursharifi_2023_Mol.Metab__101822 |
ESTHER : Poursharifi_2023_Mol.Metab__101822 |
PubMedSearch : Poursharifi_2023_Mol.Metab__101822 |
PubMedID: 37838014 |
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
Title : The serine hydrolase ABHD6 controls survival and thermally induced seizures in a mouse model of Dravet syndrome - Westenbroek_2023_Neurobiol.Dis_180_106099 |
Author(s) : Westenbroek R , Kaplan J , Viray K , Stella N |
Ref : Neurobiol Dis , 180 :106099 , 2023 |
Abstract : Westenbroek_2023_Neurobiol.Dis_180_106099 |
ESTHER : Westenbroek_2023_Neurobiol.Dis_180_106099 |
PubMedSearch : Westenbroek_2023_Neurobiol.Dis_180_106099 |
PubMedID: 36990366 |
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
Title : Alpha\/Beta-Hydrolase Domain-Containing 6: Signaling and Function in the Central Nervous System - Zhang_2021_Front.Pharmacol_12_784202 |
Author(s) : Zhang H , Li X , Liao D , Luo P , Jiang X |
Ref : Front Pharmacol , 12 :784202 , 2021 |
Abstract : Zhang_2021_Front.Pharmacol_12_784202 |
ESTHER : Zhang_2021_Front.Pharmacol_12_784202 |
PubMedSearch : Zhang_2021_Front.Pharmacol_12_784202 |
PubMedID: 34925039 |
Gene_locus related to this paper: human-ABHD6 |
Title : Evidence for a bacterial Lands cycle phospholipase A: Structural and mechanistic insights into membrane phospholipid remodeling - Bleffert_2021_Biorxiv__ |
Author(s) : Bleffert F , Granzin J , Caliskan M , Schott-Verdugo SN , Siebers M , Thiele B , Rahme L , Felgner S , Dormann P , Gohlke H , Batra-Safferling R , Jaeger KE , Kovacic F |
Ref : Biorxiv , : , 2021 |
Abstract : Bleffert_2021_Biorxiv__ |
ESTHER : Bleffert_2021_Biorxiv__ |
PubMedSearch : Bleffert_2021_Biorxiv__ |
PubMedID: |
Gene_locus related to this paper: pseae-PA2949 |
Title : Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status - Miralpeix_2021_Br.J.Pharmacol_178_1507 |
Author(s) : Miralpeix C , Reguera AC , Fosch A , Casas M , Lillo J , Navarro G , Franco R , Casas J , Alexander SPH , Casals N , Rodriguez-Rodriguez R |
Ref : British Journal of Pharmacology , 178 :1507 , 2021 |
Abstract : Miralpeix_2021_Br.J.Pharmacol_178_1507 |
ESTHER : Miralpeix_2021_Br.J.Pharmacol_178_1507 |
PubMedSearch : Miralpeix_2021_Br.J.Pharmacol_178_1507 |
PubMedID: 33444462 |
Gene_locus related to this paper: human-ABHD6 |
Title : Therapeutic potential of targeting alpha\/beta-Hydrolase domain-containing 6 (ABHD6) - Deng_2020_Eur.J.Med.Chem_198_112353 |
Author(s) : Deng H , Li W |
Ref : Eur Journal of Medicinal Chemistry , 198 :112353 , 2020 |
Abstract : Deng_2020_Eur.J.Med.Chem_198_112353 |
ESTHER : Deng_2020_Eur.J.Med.Chem_198_112353 |
PubMedSearch : Deng_2020_Eur.J.Med.Chem_198_112353 |
PubMedID: 32371333 |
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
Title : Adipose ABHD6 regulates tolerance to cold and thermogenic programs - Poursharifi_2020_JCI.Insight_5_ |
Author(s) : Poursharifi P , Attane C , Mugabo Y , Al-Mass A , Ghosh A , Schmitt C , Zhao S , Guida J , Lussier R , Erb H , Chenier I , Peyot ML , Joly E , Noll C , Carpentier AC , Madiraju SRM , Prentki M |
Ref : JCI Insight , 5 : , 2020 |
Abstract : Poursharifi_2020_JCI.Insight_5_ |
ESTHER : Poursharifi_2020_JCI.Insight_5_ |
PubMedSearch : Poursharifi_2020_JCI.Insight_5_ |
PubMedID: 33201859 |
Gene_locus related to this paper: human-ABHD6 |
Title : The alpha\/beta-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids - Bottemanne_2019_FASEB.J__fj201802259R |
Author(s) : Bottemanne P , Paquot A , Ameraoui H , Alhouayek M , Muccioli GG |
Ref : FASEB Journal , :fj201802259R , 2019 |
Abstract : Bottemanne_2019_FASEB.J__fj201802259R |
ESTHER : Bottemanne_2019_FASEB.J__fj201802259R |
PubMedSearch : Bottemanne_2019_FASEB.J__fj201802259R |
PubMedID: 30896979 |
Gene_locus related to this paper: human-ABHD6 |
Title : Cutting Edge: Dysregulated Endocannabinoid-Rheostat for Plasmacytoid Dendritic Cell Activation in a Systemic Lupus Endophenotype - Rahaman_2019_J.Immunol_202_1674 |
Author(s) : Rahaman O , Bhattacharya R , Liu CSC , Raychaudhuri D , Ghosh AR , Bandopadhyay P , Pal S , Goswami RP , Sircar G , Ghosh P , Ganguly D |
Ref : J Immunol , 202 :1674 , 2019 |
Abstract : Rahaman_2019_J.Immunol_202_1674 |
ESTHER : Rahaman_2019_J.Immunol_202_1674 |
PubMedSearch : Rahaman_2019_J.Immunol_202_1674 |
PubMedID: 30728209 |
Gene_locus related to this paper: human-ABHD6 |
Title : Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells - van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
Author(s) : van Esbroeck ACM , Kantae V , Di X , van der Wel T , den Dulk H , Stevens AF , Singh S , Bakker AT , Florea BI , Stella N , Overkleeft HS , Hankemeier T , van der Stelt M |
Ref : Front Mol Neurosci , 12 :286 , 2019 |
Abstract : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
ESTHER : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
PubMedSearch : van Esbroeck_2019_Front.Mol.Neurosci_12_286 |
PubMedID: 31849602 |
Gene_locus related to this paper: human-ABHD6 |
Title : Biochemical and Proteomic Characterization of Recombinant Human alpha\/beta Hydrolase Domain 6 - Shields_2019_Sci.Rep_9_890 |
Author(s) : Shields CM , Zvonok N , Zvonok A , Makriyannis A |
Ref : Sci Rep , 9 :890 , 2019 |
Abstract : Shields_2019_Sci.Rep_9_890 |
ESTHER : Shields_2019_Sci.Rep_9_890 |
PubMedSearch : Shields_2019_Sci.Rep_9_890 |
PubMedID: 30696836 |
Gene_locus related to this paper: human-ABHD6 |
Title : ABHD6: Its Place in Endocannabinoid Signaling and Beyond - Cao_2019_Trends.Pharmacol.Sci_40_267 |
Author(s) : Cao JK , Kaplan J , Stella N |
Ref : Trends in Pharmacological Sciences , 40 :267 , 2019 |
Abstract : Cao_2019_Trends.Pharmacol.Sci_40_267 |
ESTHER : Cao_2019_Trends.Pharmacol.Sci_40_267 |
PubMedSearch : Cao_2019_Trends.Pharmacol.Sci_40_267 |
PubMedID: 30853109 |
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
Title : Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans - Grabner_2019_J.Lipid.Res_60_1020 |
Author(s) : Grabner GF , Fawzy N , Pribasnig MA , Trieb M , Taschler U , Holzer M , Schweiger M , Wolinski H , Kolb D , Horvath A , Breinbauer R , Rulicke T , Rabl R , Lass A , Stadlbauer V , Hutter-Paier B , Stauber RE , Fickert P , Zechner R , Marsche G , Eichmann TO , Zimmermann R |
Ref : J Lipid Res , 60 :1020 , 2019 |
Abstract : Grabner_2019_J.Lipid.Res_60_1020 |
ESTHER : Grabner_2019_J.Lipid.Res_60_1020 |
PubMedSearch : Grabner_2019_J.Lipid.Res_60_1020 |
PubMedID: 30894461 |
Gene_locus related to this paper: human-ABHD6 |
Title : Structural properties and role of the endocannabinoid lipases ABHD6 and ABHD12 in lipid signalling and disease - Kind_2019_Amino.Acids_51_151 |
Author(s) : Kind L , Kursula P |
Ref : Amino Acids , 51 :151 , 2018 |
Abstract : Kind_2019_Amino.Acids_51_151 |
ESTHER : Kind_2019_Amino.Acids_51_151 |
PubMedSearch : Kind_2019_Amino.Acids_51_151 |
PubMedID: 30564946 |
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 |
Title : The Inhibitory Effect of alpha\/beta-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors - Wei_2017_Front.Mol.Neurosci_10_55 |
Author(s) : Wei M , Jia M , Zhang J , Yu L , Zhao Y , Chen Y , Ma Y , Zhang W , Shi YS , Zhang C |
Ref : Front Mol Neurosci , 10 :55 , 2017 |
Abstract : Wei_2017_Front.Mol.Neurosci_10_55 |
ESTHER : Wei_2017_Front.Mol.Neurosci_10_55 |
PubMedSearch : Wei_2017_Front.Mol.Neurosci_10_55 |
PubMedID: 28303090 |
Title : alpha\/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes - Zhao_2016_Cell.Rep_14_2872 |
Author(s) : Zhao S , Mugabo Y , Ballentine G , Attane C , Iglesias J , Poursharifi P , Zhang D , Nguyen TA , Erb H , Prentki R , Peyot ML , Joly E , Tobin S , Fulton S , Brown JM , Madiraju SR , Prentki M |
Ref : Cell Rep , 14 :2872 , 2016 |
Abstract : Zhao_2016_Cell.Rep_14_2872 |
ESTHER : Zhao_2016_Cell.Rep_14_2872 |
PubMedSearch : Zhao_2016_Cell.Rep_14_2872 |
PubMedID: 26997277 |
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
Title : alpha\/beta-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors - Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695 |
Author(s) : Wei M , Zhang J , Jia M , Yang C , Pan Y , Li S , Luo Y , Zheng J , Ji J , Chen J , Hu X , Xiong J , Shi Y , Zhang C |
Ref : Proc Natl Acad Sci U S A , 113 :E2695 , 2016 |
Abstract : Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695 |
ESTHER : Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695 |
PubMedSearch : Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695 |
PubMedID: 27114538 |
Gene_locus related to this paper: human-ABHD6 |
Title : alpha\/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal\/Lysosomal Lipid Bis(monoacylglycero)phosphate - Pribasnig_2015_J.Biol.Chem_290_29869 |
Author(s) : Pribasnig MA , Mrak I , Grabner GF , Taschler U , Knittelfelder O , Scherz B , Eichmann TO , Heier C , Grumet L , Kowaliuk J , Romauch M , Holler S , Anderl F , Wolinski H , Lass A , Breinbauer R , Marsche G , Brown JM , Zimmermann R |
Ref : Journal of Biological Chemistry , 290 :29869 , 2015 |
Abstract : Pribasnig_2015_J.Biol.Chem_290_29869 |
ESTHER : Pribasnig_2015_J.Biol.Chem_290_29869 |
PubMedSearch : Pribasnig_2015_J.Biol.Chem_290_29869 |
PubMedID: 26491015 |
Gene_locus related to this paper: human-ABHD6 |
Title : Development and optimization of piperidyl-1,2,3-triazole ureas as selective chemical probes of endocannabinoid biosynthesis - Hsu_2013_J.Med.Chem_56_8257 |
Author(s) : Hsu KL , Tsuboi K , Whitby LR , Speers AE , Pugh H , Inloes J , Cravatt BF |
Ref : Journal of Medicinal Chemistry , 56 :8257 , 2013 |
Abstract : Hsu_2013_J.Med.Chem_56_8257 |
ESTHER : Hsu_2013_J.Med.Chem_56_8257 |
PubMedSearch : Hsu_2013_J.Med.Chem_56_8257 |
PubMedID: 24152245 |
Gene_locus related to this paper: human-DAGLB |
Title : Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha\/beta-hydrolase domain containing 6 (ABHD6) - Hsu_2013_J.Med.Chem_56_8270 |
Author(s) : Hsu KL , Tsuboi K , Chang JW , Whitby LR , Speers AE , Pugh H , Cravatt BF |
Ref : Journal of Medicinal Chemistry , 56 :8270 , 2013 |
Abstract : Hsu_2013_J.Med.Chem_56_8270 |
ESTHER : Hsu_2013_J.Med.Chem_56_8270 |
PubMedSearch : Hsu_2013_J.Med.Chem_56_8270 |
PubMedID: 24152295 |
Title : The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors - Marrs_2010_Nat.Neurosci_13_951 |
Author(s) : Marrs WR , Blankman JL , Horne EA , Thomazeau A , Lin YH , Coy J , Bodor AL , Muccioli GG , Hu SS , Woodruff G , Fung S , Lafourcade M , Alexander JP , Long JZ , Li W , Xu C , Moller T , Mackie K , Manzoni OJ , Cravatt BF , Stella N |
Ref : Nat Neurosci , 13 :951 , 2010 |
Abstract : Marrs_2010_Nat.Neurosci_13_951 |
ESTHER : Marrs_2010_Nat.Neurosci_13_951 |
PubMedSearch : Marrs_2010_Nat.Neurosci_13_951 |
PubMedID: 20657592 |
Gene_locus related to this paper: human-ABHD6 |
Title : High expression of the evolutionarily conserved alpha\/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors - Max_2009_Cancer.Sci_100_2383 |
Author(s) : Max D , Hesse M , Volkmer I , Staege MS |
Ref : Cancer Sci , 100 :2383 , 2009 |
Abstract : Max_2009_Cancer.Sci_100_2383 |
ESTHER : Max_2009_Cancer.Sci_100_2383 |
PubMedSearch : Max_2009_Cancer.Sci_100_2383 |
PubMedID: 19793082 |
Gene_locus related to this paper: human-ABHD6 |
Title : An unannotated alpha\/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines - Li_2009_Mol.Biol.Rep_36_691 |
Author(s) : Li F , Fei X , Xu J , Ji C |
Ref : Mol Biol Rep , 36 :691 , 2009 |
Abstract : Li_2009_Mol.Biol.Rep_36_691 |
ESTHER : Li_2009_Mol.Biol.Rep_36_691 |
PubMedSearch : Li_2009_Mol.Biol.Rep_36_691 |
PubMedID: 18360779 |
Gene_locus related to this paper: human-ABHD6 |
Title : A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol - Blankman_2007_Chem.Biol_14_1347 |
Author(s) : Blankman JL , Simon GM , Cravatt BF |
Ref : Chemical Biology , 14 :1347 , 2007 |
Abstract : Blankman_2007_Chem.Biol_14_1347 |
ESTHER : Blankman_2007_Chem.Biol_14_1347 |
PubMedSearch : Blankman_2007_Chem.Biol_14_1347 |
PubMedID: 18096503 |
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
Title : Cloning, expression and characterization of a lipase gene (lip3) from Pseudomonas aeruginosa LST-03 - Ogino_2004_Mol.Genet.Genomics_271_189 |
Author(s) : Ogino H , Hiroshima S , Hirose S , Yasuda M , Ishimi K , Ishikawa H |
Ref : Mol Genet Genomics , 271 :189 , 2004 |
Abstract : Ogino_2004_Mol.Genet.Genomics_271_189 |
ESTHER : Ogino_2004_Mol.Genet.Genomics_271_189 |
PubMedSearch : Ogino_2004_Mol.Genet.Genomics_271_189 |
PubMedID: 14740297 |
Gene_locus related to this paper: pseae-PA2949 |
Title : Lipases for biotechnology - Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
Author(s) : Jaeger KE , Eggert T |
Ref : Curr Opin Biotechnol , 13 :390 , 2002 |
Abstract : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
ESTHER : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
PubMedSearch : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
PubMedID: 12323363 |
Title : Bacterial lipolytic enzymes: classification and properties - Arpigny_1999_Biochem.J_343_177 |
Author(s) : Arpigny JL , Jaeger KE |
Ref : Biochemical Journal , 343 :177 , 1999 |
Abstract : Arpigny_1999_Biochem.J_343_177 |
ESTHER : Arpigny_1999_Biochem.J_343_177 |
PubMedSearch : Arpigny_1999_Biochem.J_343_177 |
PubMedID: 10493927 |
Title : Nucleotide sequence of the lipase gene lip3 from the antarctic psychotroph Moraxella TA144 - Feller_1991_Biochim.Biophys.Acta_1088_323 |
Author(s) : Feller G , Thiry M , Gerday C |
Ref : Biochimica & Biophysica Acta , 1088 :323 , 1991 |
Abstract : Feller_1991_Biochim.Biophys.Acta_1088_323 |
ESTHER : Feller_1991_Biochim.Biophys.Acta_1088_323 |
PubMedSearch : Feller_1991_Biochim.Biophys.Acta_1088_323 |
PubMedID: 2001407 |
Gene_locus related to this paper: morsp-3lipa |
Structures (4)
Genes Proteins in ABHD6-Lip family (156)
Fragments of genes in ABHD6-Lip family (3)
Structures in ABHD6-Lip family (4)Substrates in ABHD6-Lip family (11)
Inhibitors in ABHD6-Lip family (34)