Kuznetsova DA, Gaynanova GA, Vasilieva EA, Pavlov RV, Zueva IV, Babaev VM, Kuznetsov DM, Voloshina AD, Petrov KA, Zakharova LY, Sinyashin OG (2022) <br />Oxime Therapy for Brain AChE Reactivation and Neuroprotection after Organophosphate Poisoning<br /><i>Pharmaceutics</i> <b>14</b>: <br /><br />Saifina LF, Abdalla M, Gubaidullina LM, Zueva IV, Eltayb WA, El-Arabey AA, Kharlamova AD, Lenina OA, Semenov VE, Petrov KA (2022) <br />Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning<br /><i>Eur Journal of Medicinal Chemistry</i> <b>246</b>: 114949<br /><br />Semenov VE, Zueva IV, Lushchekina SV, Suleimanov EG, Gubaidullina LM, Shulaeva MM, Lenina OA, Petrov KA (2022) <br />Novel Uracil-Based Inhibitors of Acetylcholinesterase with Potency for Treating Memory Impairment in an Animal Model of Alzheimer's Disease<br /><i>Molecules</i> <b>27</b>: <br /><br />Vasilieva EA, Kuznetsova DA, Valeeva FG, Kuznetsov DM, Zakharov AV, Amerhanova SK, Voloshina AD, Zueva IV, Petrov KA, Zakharova LY (2022) <br />Therapy of Organophosphate Poisoning via Intranasal Administration of 2-PAM-Loaded Chitosomes<br /><i>Pharmaceutics</i> <b>14</b>: <br /><br />Zueva IV, Lenina OA, Kayumova RM, Petrov KA, Masson P (2021) <br />Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments<br /><i>Chemico-Biological Interactions</i> <b>345</b>: 109558<br /><br />Burilova EA, Pashirova TN, Zueva IV, Gibadullina EM, Lushchekina SV, Sapunova AS, Kayumova RM, Rogov AM, Evtjugin VG, Sudakov IA, Vyshtakalyuk AB, Voloshina AD, Bukharov SV, Burilov AR, Petrov KA, Zakharova LY, Sinyashin OG (2020) <br />Bi-functional sterically hindered phenol lipid-based delivery systems as potential multi-target agents against Alzheimer's disease via an intranasal route<br /><i>Nanoscale</i> <b>12</b>: 13757<br /><br />Buzyurova DN, Pashirova TN, Zueva IV, Burilova EA, Shaihutdinova ZM, Rizvanov IK, Babaev VM, Petrov KA, Souto EB (2020) <br />Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: pharmacokinetics in rat<br /><i>Toxicology</i> <br /><br />Lenina OA, Zueva IV, Zobov VV, Semenov VE, Masson P, Petrov KA (2020) <br />Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning<br /><i>Sci Rep</i> <b>10</b>: 16611<br /><br />Pavlov RV, Gaynanova GA, Kuznetsova DA, Vasileva LA, Zueva IV, Sapunova AS, Buzyurova DN, Babaev VM, Voloshina AD, Lukashenko SS, Kh Rizvanov I, Petrov KA, Ya Zakharova L, Sinyashin OG (2020) <br />Biomedical potentialities of cationic geminis as modulating agents of liposome in drug delivery across biological barriers and cellular uptake<br /><i>Int J Pharm</i> <br /><br />Semenov VE, Zueva IV, Mukhamedyarov MA, Lushchekina SV, Petukhova EO, Gubaidullina LM, Krylova ES, Saifina LF, Lenina OA, Petrov KA (2020) <br />Novel Acetylcholinesterase Inhibitors Based on Uracil Moiety for Possible Treatment of Alzheimer Disease<br /><i>Molecules</i> <b>25</b>: <br /><br />Zueva IV, Lushchekina SV, Daude D, Chabriere E, Masson P (2020) <br />Steady-State Kinetics of Enzyme-Catalyzed Hydrolysis of Echothiophate, a P-S Bonded Organophosphorus as Monitored by Spectrofluorimetry<br /><i>Molecules</i> <b>25</b>: <br /><br />Zueva IV, Lushchekina SV, Pottie IR, Darvesh S, Masson P (2020) <br />1-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies<br /><i>Biomolecules</i> <b>10</b>: <br /><br />Grigorenko BL, Novichkova DA, Lushchekina SV, Zueva IV, Schopfer LM, Nemukhin AV, Varfolomeev SD, Lockridge O, Masson P (2019) <br />Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad<br /><i>Chemico-Biological Interactions</i> <b>306</b>: 138<br /><br />Mukhametgalieva AR, Zueva IV, Aglyamova AR, Lushchekina SV, Masson P (2019) <br />A new sensitive spectrofluorimetric method for measurement of activity and kinetic study of cholinesterases<br /><i>Biochimica & Biophysica Acta Proteins Proteom</i> <br /><br />Padnya PL, Bayarashov EE, Zueva IV, Lushchekina SV, Lenina OA, Evtugyn VG, Osin YN, Petrov KA, Stoikov, II (2019) <br />Water-soluble betaines and amines based on thiacalix[4]arene scaffold as new cholinesterase inhibitors<br /><i>Bioorg Chem</i> <br /><br />Pashirova TN, Burilova EA, Tagasheva RG, Zueva IV, Gibadullina EM, Nizameev IR, Sudakov IA, Vishtakalyk AB, Voloshina AD, Kadirov MK, Petrov KA, Burilov AR, Bukharov SV, Zakharova LY (2019) <br />Delivery nanosystems based on sterically hindered phenol derivatives containing a quaternary ammonium moiety: Synthesis, cholinesterase inhibition and antioxidant activity<br /><i>Chemico-Biological Interactions</i> <br /><br />Semenov VE, Zueva IV, Lushchekina SV, Lenina OA, Gubaidullina LM, Saifina LF, Shulaeva MM, Kayumova RM, Saifina AF, Gubaidullin AT, Kondrashova SA, Latypov SK, Masson P, Petrov KA (2019) <br />6-Methyluracil derivatives as peripheral site ligand-hydroxamic acid conjugates: Reactivation for paraoxon-inhibited acetylcholinesterase<br /><i>Eur Journal of Medicinal Chemistry</i> <b>185</b>: 111787<br /><br />Zueva IV, Dias J, Lushchekina SV, Semenov VE, Mukhamedyarov MA, Pashirova TN, Babaev VM, Nachon F, Petrova N, Nurullin LF, Zakharova LY, Ilyin VI, Masson P, Petrov KA (2019) <br />New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease<br /><i>Neuropharmacology</i> <b>155</b>: 131<br /><br />Pashirova TN, Zueva IV, Petrov KA, Lukashenko SS, Nizameev IR, Kulik NV, Voloshina AD, Almasy L, Kadirov MK, Masson P, Souto EB, Zakharova LY, Sinyashin OG (2018) <br />Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model<br /><i>Colloids Surf B Biointerfaces</i> <b>171</b>: 358<br /><br />Pashirova TN, Braiki A, Zueva IV, Petrov KA, Babaev VM, Burilova EA, Samarkina DA, Rizvanov IK, Souto EB, Jean L, Renard PY, Masson P, Zakharova LY, Sinyashin OG (2018) <br />Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection<br /><i>J Control Release</i> <b>290</b>: 102<br /><br />Petrov KA, Kharlamova AD, Lenina OA, Nurtdinov AR, Sitdykova ME, Ilyin VI, Zueva IV, Nikolsky EE (2018) <br />Specific inhibition of acetylcholinesterase as an approach to decrease muscarinic side effects during myasthenia gravis treatment<br /><i>Sci Rep</i> <b>8</b>: 304<br /><br />Petrov KA, Zueva IV, Kovyazina IV, Sedov I, Lushchekina SV, Kharlamova AD, Lenina O, Koshkin S, Shtyrlin Y, Nikolsky EE, Masson P (2018) <br />C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies<br /><i>Neuropharmacology</i> <b>131</b>: 304<br /><br />Zueva IV, Lushchekina SV, Masson P (2018) <br />Water structure changes in oxime-mediated reactivation process of phosphorylated human acetylcholinesterase<br /><i>Bioscience Reports</i> <b>38</b>: <br /><br />Pashirova TN, Zueva IV, Petrov KA, Babaev VM, Lukashenko SS, Rizvanov IK, Souto EB, Nikolsky EE, Zakharova LY, Masson P, Sinyashin OG (2017) <br />Nanoparticle-Delivered 2-PAM for Rat Brain Protection against Paraoxon Central Toxicity<br /><i>ACS Appl Mater Interfaces</i> <b>9</b>: 16922<br /><br />Kharlamova AD, Lushchekina SV, Petrov KA, Kots ED, Nachon F, Villard-Wandhammer M, Zueva IV, Krejci E, Reznik VS, Zobov VV, Nikolsky EE, Masson P (2016) <br />Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment<br /><i>Biochemical Journal</i> <b>473</b>: 1225<br /><br />Strelnik AD, Petukhov AS, Zueva IV, Zobov VV, Petrov KA, Nikolsky EE, Balakin KV, Bachurin SO, Shtyrlin YG (2016) <br />Novel potent pyridoxine-based inhibitors of AChE and BChE, structural analogs of pyridostigmine, with improved in vivo safety profile<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>26</b>: 4092<br /><br />Mukhametshina AR, Fedorenko SV, Zueva IV, Petrov KA, Masson P, Nizameev IR, Mustafina AR, Sinyashin OG (2015) <br />Luminescent silica nanoparticles for sensing acetylcholinesterase-catalyzed hydrolysis of acetylcholine<br /><i>Biosensors & Bioelectronics</i> <b>77</b>: 871<br /><br />Semenov VE, Zueva IV, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS (2015) <br />6-Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease<br /><i>ChemMedChem</i> <b>10</b>: 1863<br /><br />Zueva IV, Semenov VE, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS (2015) <br />6-Methyluracil derivatives as acetylcholinesterase inhibitors for treatment of Alzheimer's disease<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S69<br /><br />