Yamada N, Negoro R, Watanabe K, Fujita T (2023)
Generation of Caco-2cells with predictable metabolism by CYP3A4, UGT1A1 and CES using the PITCh system
Drug Metab Pharmacokinet 50: 100497

Oshima E, Takenoshita S, Iwai R, Yabe M, Imai N, Horiuchi M, Takeda N, Uchitomi Y, Yamada N, Terada S (2019)
Competency of aMCI patients to consent to cholinesterase treatment
Int Psychogeriatr

Wakiya T, Sanada Y, Urahashi T, Ihara Y, Yamada N, Okada N, Hirata Y, Hakamada K, Yasuda Y, Mizuta K (2015)
Impact of the serum ferritin concentration in liver transplantation
Liver Transpl 21: 1419

Gotoda T, Shirai K, Ohta T, Kobayashi J, Yokoyama S, Oikawa S, Bujo H, Ishibashi S, Arai H, Yamashita S, Harada-Shiba M, Eto M, Hayashi T, Sone H, Suzuki H, Yamada N (2012)
Diagnosis and management of type I and type V hyperlipoproteinemia
J Atheroscler Thromb 19: 1

Sekiya M, Osuga J, Yahagi N, Okazaki H, Tamura Y, Igarashi M, Takase S, Harada K, Okazaki S, Iizuka Y, Ohashi K, Yagyu H, Okazaki M, Gotoda T, Nagai R, Kadowaki T, Shimano H, Yamada N, Ishibashi S (2008)
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
J Lipid Res 49: 1829

Ito K, Nakajima Y, Xu Y, Yamada N, Onohara Y, Ito T, Matsubara F, Kabashima T, Nakayama K, Yoshimoto T (2006)
Crystal structure and mechanism of tripeptidyl activity of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis
Journal of Molecular Biology 362: 228

Okazaki H, Igarashi M, Nishi M, Tajima M, Sekiya M, Okazaki S, Yahagi N, Ohashi K, Tsukamoto K, Amemiya-Kudo M, Matsuzaka T, Shimano H, Yamada N, Aoki J, Morikawa R, Takanezawa Y, Arai H, Nagai R, Kadowaki T, Osuga J, Ishibashi S (2006)
Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis
Diabetes 55: 2091

Arai H, Yamamoto A, Matsuzawa Y, Saito Y, Yamada N, Oikawa S, Mabuchi H, Teramoto T, Sasaki J, Nakaya N, Itakura H, Ishikawa Y, Ouchi Y, Horibe H, Egashira T, Hattori H, Shirahashi N, Kita T (2005)
Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000
J Atheroscler Thromb 12: 240

Ichikawa T, Liang J, Kitajima S, Koike T, Wang X, Sun H, Morimoto M, Shikama H, Watanabe T, Yamada N, Fan J (2005)
Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits
Atherosclerosis 179: 87

Liu E, Kitajima S, Higaki Y, Morimoto M, Sun H, Watanabe T, Yamada N, Fan J (2005)
High lipoprotein lipase activity increases insulin sensitivity in transgenic rabbits
Metabolism 54: 132

Nakajima Y, Ito K, Xu Y, Yamada N, Onohara Y, Ito T, Yoshimoto T (2005)
Crystallization and preliminary X-ray characterization of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis
Acta Crystallographica Sect F Struct Biol Cryst Commun 61: 1046

Ichikawa T, Kitajima S, Liang J, Koike T, Wang X, Sun H, Okazaki M, Morimoto M, Shikama H, Watanabe T, Yamada N, Fan J (2004)
Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis
Lab Invest 84: 715

Kitajima S, Morimoto M, Liu E, Koike T, Higaki Y, Taura Y, Mamba K, Itamoto K, Watanabe T, Tsutsumi K, Yamada N, Fan J (2004)
Overexpression of lipoprotein lipase improves insulin resistance induced by a high-fat diet in transgenic rabbits
Diabetologia 47: 1202

Maruyama T, Yamashita S, Matsuzawa Y, Bujo H, Takahashi K, Saito Y, Ishibashi S, Ohashi K, Shionoiri F, Gotoda T, Yamada N, Kita T (2004)
Mutations in Japanese subjects with primary hyperlipidemia--results from the Research Committee of the Ministry of Health and Welfare of Japan since 1996
J Atheroscler Thromb 11: 131

Sekiya M, Osuga J, Okazaki H, Yahagi N, Harada K, Shen WJ, Tamura Y, Tomita S, Iizuka Y, Ohashi K, Okazaki M, Sata M, Nagai R, Fujita T, Shimano H, Kraemer FB, Yamada N, Ishibashi S (2004)
Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice
Journal of Biological Chemistry 279: 15084

Yamada N, Hattori A, Hayashi T, Nishikawa T, Fukuda H, Fujino T (2004)
Improvement of scopolamine-induced memory impairment by Z-ajoene in the water maze in mice
Pharmacol Biochem Behav 78: 787

Abe Y, Aoyagi A, Hara T, Abe K, Yamazaki R, Kumagae Y, Naruto S, Koyama K, Marumoto S, Tago K, Toda N, Takami K, Yamada N, Ori M, Kogen H, Kaneko T (2003)
Pharmacological characterization of RS-1259, an orally active dual inhibitor of acetylcholinesterase and serotonin transporter, in rodents: possible treatment of Alzheimer's disease
J Pharmacol Sci 93: 95

Toda N, Tago K, Marumoto S, Takami K, Ori M, Yamada N, Koyama K, Naruto S, Abe K, Yamazaki R, Hara T, Aoyagi A, Abe Y, Kaneko T, Kogen H (2003)
Design, synthesis and structure-Activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease
Bioorganic & Medicinal Chemistry 11: 1935

Toda N, Tago K, Marumoto S, Takami K, Ori M, Yamada N, Koyama K, Naruto S, Abe K, Yamazaki R, Hara T, Aoyagi A, Abe Y, Kaneko T, Kogen H (2003)
A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease
Bioorganic & Medicinal Chemistry 11: 4389

Kogen H, Toda N, Tago K, Marumoto S, Takami K, Ori M, Yamada N, Koyama K, Naruto S, Abe K, Yamazaki R, Hara T, Aoyagi A, Abe Y, Kaneko T (2002)
Design and synthesis of dual inhibitors of acetylcholinesterase and serotonin transporter targeting potential agents for Alzheimer's disease
Org Lett 4: 3359

Shoop RD, Esquenazi E, Yamada N, Ellisman MH, Berg DK (2002)
Ultrastructure of a somatic spine mat for nicotinic signaling in neurons
Journal of Neuroscience 22: 748

Tanaka S, Hamada K, Yamada N, Sugita Y, Tonai S, Hunyady B, Palkovits M, Falus A, Watanabe T, Okabe S, Ohtsu H, Ichikawa A, Nagy A (2002)
Gastric acid secretion in L-histidine decarboxylase-deficient mice
Gastroenterology 122: 145

Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N (2002)
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice
Journal of Biological Chemistry 277: 19353

Araki M, Fan J, Challah M, Bensadoun A, Yamada N, Honda K, Watanabe T (2000)
Transgenic rabbits expressing human lipoprotein lipase
Cytotechnology 33: 93

Osuga J, Ishibashi S, Oka T, Yagyu H, Tozawa R, Fujimoto A, Shionoiri F, Yahagi N, Kraemer FB, Tsutsumi O, Yamada N (2000)
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
Proc Natl Acad Sci U S A 97: 787

Shoop RD, Yamada N, Berg DK (2000)
Cytoskeletal links of neuronal acetylcholine receptors containing alpha 7 subunits
Journal of Neuroscience 20: 4021

Yoshida T, Gotoda T, Okubo M, Iizuka Y, Ishibashi S, Kojima T, Murakami T, Murase T, Yamada N (2000)
A Japanese patient with lipoprotein lipase deficiency homozygous for the Gly188Glu mutation prevalent worldwide
J Atheroscler Thromb 7: 45

Okubo M, Inoue S, Horinishi A, Ogihara T, Kaneko K, Gotoda T, Yamada N, Murase T (1999)
Detection of a new compound heterozygote (del G916/G1401A) for lipoprotein lipase deficiency and a comparative haplotype analysis of the mutant lipoprotein lipase gene from Japanese patients
Atherosclerosis 144: 443

Shoop RD, Martone ME, Yamada N, Ellisman MH, Berg DK (1999)
Neuronal acetylcholine receptors with alpha7 subunits are concentrated on somatic spines for synaptic signaling in embryonic chick ciliary ganglia
Journal of Neuroscience 19: 692

Osuga J, Ishibashi S, Shimano H, Inaba T, Kawamura M, Yazaki Y, Yamada N (1997)
Suppression of neutral cholesterol ester hydrolase activity by antisense DNA of hormone-sensitive lipase
Biochemical & Biophysical Research Communications 233: 655

Gotoda T, Yamada N, Murase T, Miyake S, Murakami R, Kawamura M, Kozaki K, Mori N, Shimano H, Shimada M, Yazaki Y (1992)
A newly identified null allelic mutation in the human lipoprotein lipase (LPL) gene of a compound heterozygote with familial LPL deficiency
Biochimica & Biophysica Acta 1138: 353

Gotoda T, Yamada N, Murase T, Shimano H, Shimada M, Harada K, Kawamura M, Kozaki K, Yazaki Y (1992)
Detection of three separate DNA polymorphisms in the human lipoprotein lipase gene by gene amplification and restriction endonuclease digestion
J Lipid Res 33: 1067

Gotoda T, Yamada N, Kawamura M, Kozaki K, Mori N, Ishibashi S, Shimano H, Takaku F, Yazaki Y, Furuichi Y, et al. (1991)
Heterogeneous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency
J Clinical Investigation 88: 1856

Gotoda T, Yamada N, Murase T, Sakuma M, Murayama N, Shimano H, Kozaki K, Albers JJ, Yazaki Y, Akanuma Y (1991)
Differential phenotypic expression by three mutant alleles in familial lecithin:cholesterol acyltransferase deficiency
Lancet 338: 778

Gotoda T, Senda M, Murase T, Yamada N, Takaku F, Furuichi Y (1989)
Detection of familial LPL deficiency by PvuII RFLP
Nucleic Acids Research 17: 3607

Gotoda T, Senda M, Murase T, Yamada N, Takaku F, Furuichi Y (1989)
Gene polymorphism identified by PvuII in familial lipoprotein lipase deficiency
Biochemical & Biophysical Research Communications 164: 1391

Sakuma M, Akanuma Y, Kodama T, Yamada N, Murata S, Murase T, Itakura H, Kosaka K (1982)
Familial plasma lecithin: cholesterol acyltransferase deficiency. A new family with partial LCAT activity
Acta Med Scand 212: 225