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Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases
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Li Z, Zhang B, Liu Q, Tao Z, Ding L, Guo B, Zhang E, Zhang H, Meng Z, Guo S, Chen Y, Peng J, Li J, Wang C, Huang Y, Xu H, Wu Y (2023)
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Liu K, Sun L, Li S, Xu H (2023)
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Lu Y, Zheng X, He X, Guo J, Fu Q, Xu H, Lu Z (2023)
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Xu H, Ge H, Shan X, Cai Z (2023)
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Xu J, Lv M, Fang S, Wang Y, Wen H, Zhang S, Xu H (2023)
Exploration of Synergistic Pesticidal Activities, Control Effects and Toxicology Study of a Monoterpene Essential Oil with Two Natural Alkaloids
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Hao M, Lv M, Zhou L, Li H, Xu J, Xu H (2022)
Construction, Pesticidal Activities, Control Effects, and Detoxification Enzyme Activities of Osthole Ester/Amide Derivatives
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Li J, Wang Y, Yang P, Han H, Zhang G, Xu H, Quan K (2022)
Overexpression of ATGL impairs lipid droplet accumulation by accelerating lipolysis in goat mammary epithelial cells
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Xiao ZJ, Liu SX, Zou B, Cheng HH, Xu H, Huang ZH, Shu SN (2022)
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Xu H, Lyu X, Guo X, Yang H, Duan L, Zhu H, Pan H, Gong F, Wang L (2022)
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Xu H, Garcia-Ptacek S, Bruchfeld A, Fu EL, Shori TD, Lindholm B, Eriksdotter M, Carrero JJ (2022)
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Xu J, Xie X, Ma Q, Zhang L, Li Y, Chen Y, Li K, Xiao Y, Tettamanti G, Xu H, Tian L (2022)
Identification of Host Molecules Involved in the Proliferation of Nucleopolyhedrovirus in Bombyx mori
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Yuan M, Hu W, Feng Y, Tong Y, Wang X, Tan B, Xu H, Liu J (2022)
Development and validation of a LC-MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice
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Zhao Y, Li W, Sun L, Xu H, Su W, Xue F, Wu R, Lu C (2022)
Transcriptome analysis and the identification of genes involved in the metabolic pathways of fenoxaprop-P-ethyl in rice treated with isoxadifen-ethyl hydrolysate
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Chen K, Wu M, Chen C, Xu H, Wu X, Qiu X (2021)
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Hou L, Rong J, Haider A, Ogasawara D, Varlow C, Schafroth MA, Mu L, Gan J, Xu H, Fowler CJ, Zhang MR, Vasdev N, Ametamey S, Cravatt BF, Wang L, Liang SH (2021)
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Mo Q, Yang X, Wang J, Xu H, Li W, Fan Q, Gao S, Yang W, Gao C, Liao D, Li Y, Zhang Y (2021)
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Rong J, Mori W, Xia X, Schafroth MA, Zhao C, Van RS, Yamasaki T, Chen J, Xiao Z, Haider A, Ogasawara D, Hiraishi A, Shao T, Zhang Y, Chen Z, Pang F, Hu K, Xie L, Fujinaga M, Kumata K, Gou Y, Fang Y, Gu S, Wei H, Bao L, Xu H, Collier TL, Shao Y, Carson RE, Cravatt BF, Wang L, Zhang MR, Liang SH (2021)
Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold
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Xiong F, Ding X, Zhang H, Luo X, Chen K, Jiang H, Luo C, Xu H (2021)
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Xu H, Garcia-Ptacek S, Jonsson L, Anders W, Nordstrom P, Eriksdotter M (2021)
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Construction of Peroxidase-like Metal-Organic Frameworks in TiO(2) Nanochannels: Robust Free-Standing Membranes for Diverse Target Sensing
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Xu H, Li YM, Yi Y, Zheng YW, Ohkohchi N (2021)
The Effect of the Platelet Administration for the Patients with Liver Dysfunction after Liver Resection: Preliminary Clinical Trial
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Xu H, Zhou Q, Liu B, Cheng KW, Chen F, Wang M (2021)
Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
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Xu H, Li X, Xin X, Mo L, Zou Y, Zhao G (2021)
Efficient Enzymatic Synthesis of Lipophilic Phenolic Glycoside Azelaic Acid Esters and Their Depigmenting Activity
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Xu H, Garcia-Ptacek S, Eriksdotter M (2021)
Author Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
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Zhao C, Chen M, Sun SL, Wang JJ, Zhong Y, Chen HH, Li HM, Xu H, Li NG, Ma HY, Wang XL (2021)
Bufotenine and its derivatives: synthesis, analgesic effects identification and computational target prediction
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Du H, Jiang X, Ma M, Xu H, Liu S, Ma F (2020)
Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation
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Fu Y, Lu Z, Ma X, Fang K, He X, Xu H, Hu Y (2020)
One-pot cascade synthesis of benzopyrans and dihydropyrano[c]chromenes catalyzed by lipase TLIM
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Gyimah E, Dong X, Qiu W, Zhang Z, Xu H (2020)
Sublethal concentrations of triclosan elicited oxidative stress, DNA damage, and histological alterations in the liver and brain of adult zebrafish
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Huang P, Huang C, Xu H, Lu J, Tian R, Wang Z, Chen Y (2020)
Early Use of Blood Purification in Severe Epstein-Barr Virus-Associated Hemophagocytic Syndrome

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The muscarinic agonist pilocarpine modifies cocaine-reinforced and food-reinforced responding in rats: comparison with the cholinesterase inhibitor tacrine
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Li S, Qin C, Cui S, Xu H, Wu F, Wang J, Su M, Fang X, Li D, Jiao Q, Zhang M, Xia C, Zhu L, Wang R, Li J, Jiang H, Zhao Z, Li H (2019)
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
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Li YT, Ye JZ, Lv LX, Xu H, Yang LY, Jiang XW, Wu WR, Shi D, Fang DQ, Bian XY, Wang KC, Wang QQ, Xie JJ, Lu YM, Li LJ (2019)
Pretreatment With Bacillus cereus Preserves Against D-Galactosamine-Induced Liver Injury in a Rat Model
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Xu H, Chen L, Zhang X, Jiang X, Tian W, Yu W, Wang X, Tian J, Su D (2019)
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Fu H, Xia Y, Chen Y, Xu T, Xu L, Guo Z, Xu H, Xie HQ, Zhao B (2018)
Acetylcholinesterase Is a Potential Biomarker for a Broad Spectrum of Organic Environmental Pollutants
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Jiang X, Chen G, Huang J, Xie L, Shen D, Jiang K, Xu H (2018)
Modified Buzhong Yiqi decoction for myasthenia gravis: A systematic review protocol
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Pan C, Yang M, Xu H, Xu B, Jiang L, Wu M (2018)
Tissue bioconcentration and effects of fluoxetine in zebrafish (Danio rerio) and red crucian cap (Carassius auratus) after short-term and long-term exposure
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Xie Y, Zeng H, Huang Z, Xu H, Fan Q, Zhang Y, Zheng B (2018)
Effect of Maternal Administration of Edible Bird's Nest on the Learning and Memory Abilities of Suckling Offspring in Mice
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Yang Y, Xu H, Lu Y, Wang C, Lu Z (2018)
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Lan D, Xu H, Xu J, Dubin G, Liu J, Iqbal Khan F, Wang Y (2017)
Malassezia globosa MgMDL2 lipase: Crystal structure and rational modification of substrate specificity
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Reyes-Chin-Wo S, Wang Z, Yang X, Kozik A, Arikit S, Song C, Xia L, Froenicke L, Lavelle DO, Truco MJ, Xia R, Zhu S, Xu C, Xu H, Xu X, Cox K, Korf I, Meyers BC, Michelmore RW (2017)
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Zeng Z, Yan Y, Wang B, Liu N, Xu H (2017)
Discovery and identification of O, O-diethyl O-(4-(5-phenyl-4, 5-dihydroisoxazol-3-yl) phenyl) phosphorothioate (XP-1408) as a novel mode of action of organophosphorus insecticides
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Faure G, Bakouh N, Lourdel S, Odolczyk N, Premchandar A, Servel N, Hatton A, Ostrowski MK, Xu H, Saul FA, Moquereau C, Bitam S, Pranke I, Planelles G, Teulon J, Herrmann H, Roldan A, Zielenkiewicz P, Dadlez M, Lukacs GL, Sermet-Gaudelus I, Ollero M, Corringer PJ, Edelman A (2016)
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Li S, Xu H, Cui S, Wu F, Zhang Y, Su M, Gong Y, Qiu S, Jiao Q, Qin C, Shan J, Zhang M, Wang J, Yin Q, Xu M, Liu X, Wang R, Zhu L, Li J, Xu Y, Jiang H, Zhao Z, Li H (2016)
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Wang H, Xu H, Wang X, Wu R, Gao X, Jin Q, Niu J (2016)
Red Blood Cell Distribution Width to Platelet Ratio is Related to Histologic Severity of Primary Biliary Cirrhosis
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Guo Q, Du G, He H, Xu H, Guo D, Li R (2015)
Two nematicidal furocoumarins from Ficus carica L. leaves and their physiological effects on pine wood nematode (Bursaphelenchus xylophilus)
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Ma Q, Ruan YY, Xu H, Shi XM, Wang ZX, Hu YL (2015)
Safflower yellow reduces lipid peroxidation, neuropathology, tau phosphorylation and ameliorates amyloid beta-induced impairment of learning and memory in rats
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Xu H, Tao X, Wei Y, Chen J, Xing S, Cen W, Wen A, Zhu L, Tang G, Li M, Jiang A, Jiang Y, Li X (2015)
Cloning of porcine GPIHBP1 gene and its tissue expression pattern and genetic effect on adipose traits
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Xu H, Lan D, Yang B, Wang Y (2015)
Biochemical Properties and Structure Analysis of a DAG-Like Lipase from Malassezia globosa
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Xu H, Yan Q, Duan X, Yang S, Jiang Z (2015)
Characterization of an acidic cold-adapted cutinase from Thielavia terrestris and its application in flavor ester synthesis
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Xu H, Majmudar JD, Davda D, Ghanakota P, Kim KH, Carlson HA, Showalter HD, Martin BR, Amidon GL (2015)
Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes
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Zhao F, Li T, Zhang C, Xu Y, Xu H, Shi N (2015)
[Effects of methomyl on acetylcholinesterase in erythrocyte membrane and various brain areas]
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Chen Z, Lei X, Lai Q, Li Y, Zhang B, Zhang J, Zhang H, Yang L, Zheng W, Tian Y, Yu Z, Xu H, Zheng T (2014)
Phaeodactylibacter xiamenensis gen. nov., sp. nov., a member of the family Saprospiraceae isolated from the marine alga Phaeodactylum tricornutum
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Jiang S, Li Y, Zhang C, Zhao Y, Bu G, Xu H, Zhang YW (2014)
M1 muscarinic acetylcholine receptor in Alzheimer's disease
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McCreedy DA, Brown CR, Butts JC, Xu H, Huettner JE, Sakiyama-Elbert SE (2014)
A new method for generating high purity motoneurons from mouse embryonic stem cells
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Xu H, Shen Z, Xiao J, Yang Y, Huang W, Zhou Z, Shen J, Zhu Y, Liu XY, Chu L (2014)
Acetylcholinesterase overexpression mediated by oncolytic adenovirus exhibited potent anti-tumor effect
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Yan Q, Yang S, Duan X, Xu H, Liu Y, Jiang Z (2014)
Characterization of a novel hormone-sensitive lipase family esterase from Rhizomucor miehei with tertiary alcohol hydrolysis activity
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Cao Z, Mulvihill MM, Mukhopadhyay P, Xu H, Erdelyi K, Hao E, Holovac E, Hasko G, Cravatt BF, Nomura DK, Pacher P (2013)
Monoacylglycerol lipase controls endocannabinoid and eicosanoid signaling and hepatic injury in mice
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Chen J, Lu Z, Zhang M, Zhang J, Ni X, Jiang X, Xu H, Heeramun-Aubeeluck A, Hu Q, Jin H, Davis JM (2013)
A randomized, 4-week double-blind placebo control study on the efficacy of donepezil augmentation of lithium for treatment of acute mania
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Guo F, Xu H, Yu H (2013)
Compensation of the enantioselectivity-activity trade-off in the directed evolution of an esterase from Rhodobacter sphaeroides by site-directed saturation mutagenesis
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Li W, Zheng B, Xu H, Deng Y, Wang S, Wang X, Su D (2013)
Isoflurane prevents neurocognitive dysfunction after cardiopulmonary bypass in rats
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Liu Y, Xu H, Yan Q, Yang S, Duan X, Jiang Z (2013)
Biochemical characterization of a first fungal esterase from Rhizomucor miehei showing high efficiency of ester synthesis
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Shen Y, Li B, Xu H, Zhang G (2013)
Design, synthesis, and biological evaluation of acetophenone derivatives as dual binding acetylcholinesterase inhibitors
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Xu H, Shao X, Zhang Z, Zou Y, Chen Y, Han S, Wang S, Wu X, Yang L, Chen Z (2013)
Effects of Di-n-butyl Phthalate and Diethyl Phthalate on Acetylcholinesterase Activity and Neurotoxicity Related Gene Expression in Embryonic Zebrafish
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Yang S, Xu H, Yan Q, Liu Y, Zhou P, Jiang Z (2013)
A low molecular mass cutinase of Thielavia terrestris efficiently hydrolyzes poly(esters)
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Fan C, Yu J, Liu Y, Xu H, Wang E (2012)
Increased NDRG1 expression is associated with advanced T stages and poor vascularization in non-small cell lung cancer
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Xie H, Zeng L, Zeng S, Lu X, Zhang G, Zhao X, Cheng N, Tu Z, Li Z, Xu H, Yang L, Zhang X, Huang M, Zhao J, Hu W (2012)
Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization
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Xu H, Su ZR, Huang W, Choi RC, Zheng YZ, Lau DT, Dong TTX, Wang ZT, Tsim KWK (2012)
Er Zhi Wan, an ancient herbal decoction for woman menopausal syndrome, activates the estrogenic response in cultured MCF-7 cells: an evaluation of compatibility in defining the optimized preparation method
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Xu SL, Choi RC, Zhu KY, Leung KW, Guo AJ, Bi D, Xu H, Lau DT, Dong TTX, Tsim KWK (2012)
Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
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Chin CL, Carr RA, Llano DA, Barret O, Xu H, Batis J, Koren AO, Seibyl JP, Marsh KC, Tamagnan G, Decker MW, Day M, Fox GB (2011)
Pharmacokinetic modeling and [(1)(2)(3)]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089
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Faure G, Xu H, Saul FA (2011)
Crystal structure of crotoxin reveals key residues involved in the stability and toxicity of this potent heterodimeric beta-neurotoxin
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Su D, Zhao Y, Wang B, Xu H, Li W, Chen J, Wang X (2011)
Isoflurane-induced spatial memory impairment in mice is prevented by the acetylcholinesterase inhibitor donepezil
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Sink KM, Thomas J, 3rd, Xu H, Craig B, Kritchevsky S, Sands LP (2008)
Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes
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Tietje KR, Anderson DJ, Bitner RS, Blomme EA, Brackemeyer PJ, Briggs CA, Browman KE, Bury D, Curzon P, Drescher KU, Frost JM, Fryer RM, Fox GB, Gronlien JH, Hakerud M, Gubbins EJ, Halm S, Harris R, Helfrich RJ, Kohlhaas KL, Law D, Malysz J, Marsh KC, Martin RL, Meyer MD, Molesky AL, Nikkel AL, Otte S, Pan L, Puttfarcken PS, Radek RJ, Robb HM, Spies E, Thorin-Hagene K, Waring JF, Ween H, Xu H, Gopalakrishnan M, Bunnelle WH (2008)
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
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Xia Q, Wang J, Zhou Z, Li R, Fan W, Cheng D, Cheng T, Qin J, Duana J, Xu H, Li Q, Li N, Wang M, Dai F, Liu C, Lin Y, Zhao P, Zhang H, Liu S, Zha X, Li C, Zhao A, Pan M, Pan G, Shen Y, Gao Z, Wang Z, Wang G, Wu Z, Hou Y, Chai C, Yu Q, He N, Zhang Z, Li S, Yang H, Lu C, Xiang Z, Mita K, Kasahara M, Nakatani Y, Yamamoto K, Abe H, Ahsan B, Daimoni T, Doi K, Fujii T, Fujiwara H, Fujiyama A, Futahashi R, Hashimotol S, Ishibashi J, Iwami M, Kadono-Okuda K, Kanamori H, Kataoka H, Katsuma S, Kawaoka S, Kawasaki H, Kohara Y, Kozaki T, Kuroshu RM, Kuwazaki S, Matsushima K, Minami H, Nagayasu Y, Nakagawa T, Narukawa J, Nohata J, Ohishi K, Ono Y, Osanai-Futahashi M, Ozaki K, Qu W, Roller L, Sasaki S, Sasaki T, Seino A, Shimomura M, Shin-I T, Shinoda T, Shiotsuki T, Suetsugu Y, Sugano S, Suwa M, Suzuki Y, Takiya S, Tamura T, Tanaka H, Tanaka Y, Touhara K, Yamada T, Yamakawa M, Yamanaka N, Yoshikawa H, Zhong YS, Shimada T, Morishita S (2008)
The genome of a lepidopteran model insect, the silkworm Bombyx mori
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Gao P, Xu H, Ding P, Gao Q, Sun J, Chen D (2007)
Controlled release of huperzine A from biodegradable microspheres: In vitro and in vivo studies
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Wang M, Liu L, Wang Y, Wei Z, Zhang P, Li Y, Jiang X, Xu H, Gong W (2007)
Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans
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Bai L, Li L, Xu H, Minagawa K, Yu Y, Zhang Y, Zhou X, Floss HG, Mahmud T, Deng Z (2006)
Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A
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Gao P, Ding P, Xu H, Yuan Z, Chen D, Wei J (2006)
In vitro and in vivo characterization of huperzine a loaded microspheres made from end-group uncapped poly(d,l-lactide acid) and poly(d,l-lactide-co-glycolide acid)
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Maresh JG, Xu H, Jiang N, Gairola CG, Shohet RV (2005)
Tobacco smoke dysregulates endothelial vasoregulatory transcripts in vivo
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Yu J, Wang J, Lin W, Li S, Li H, Zhou J, Ni P, Dong W, Hu S, Zeng C, Zhang J, Zhang Y, Li R, Xu Z, Li X, Zheng H, Cong L, Lin L, Yin J, Geng J, Li G, Shi J, Liu J, Lv H, Li J, Deng Y, Ran L, Shi X, Wang X, Wu Q, Li C, Ren X, Li D, Liu D, Zhang X, Ji Z, Zhao W, Sun Y, Zhang Z, Bao J, Han Y, Dong L, Ji J, Chen P, Wu S, Xiao Y, Bu D, Tan J, Yang L, Ye C, Xu J, Zhou Y, Yu Y, Zhang B, Zhuang S, Wei H, Liu B, Lei M, Yu H, Li Y, Xu H, Wei S, He X, Fang L, Huang X, Su Z, Tong W, Tong Z, Ye J, Wang L, Lei T, Chen C, Chen H, Huang H, Zhang F, Li N, Zhao C, Huang Y, Li L, Xi Y, Qi Q, Li W, Hu W, Tian X, Jiao Y, Liang X, Jin J, Gao L, Zheng W, Hao B, Liu S, Wang W, Yuan L, Cao M, McDermott J, Samudrala R, Wong GK, Yang H (2005)
The Genomes of Oryza sativa: a history of duplications
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Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, Li H, Qiu X, Zhong F, He L, Yu J, Yao G, Jiang H, Qian L, Yu Y, Shu H, Chen X, Xu H, Guo M, Pan Z, Chen Y, Ge C, Yang S, Gu J (2004)
Large-scale cDNA transfection screening for genes related to cancer development and progression
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Ren SX, Fu G, Jiang XG, Zeng R, Miao YG, Xu H, Zhang YX, Xiong H, Lu G, Lu LF, Jiang HQ, Jia J, Tu YF, Jiang JX, Gu WY, Zhang YQ, Cai Z, Sheng HH, Yin HF, Zhang Y, Zhu GF, Wan M, Huang HL, Qian Z, Wang SY, Ma W, Yao ZJ, Shen Y, Qiang BQ, Xia QC, Guo XK, Danchin A, Saint Girons I, Somerville RL, Wen YM, Shi MH, Chen Z, Xu JG, Zhao GP (2003)
Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
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Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, Xu H, Green WN, Koo EH, Thinakaran G (2002)
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[Studies on tissue culture of Dendrobium chrysotoxum Lindl in vitro]
Zhongguo Zhong Yao Za Zhi 26: 378

Li M, Xu H, Chen CQ (2000)
High-efficiency Expression of Prolyl Endopeptidase from Aeromonas punctata subsp. Punctata in Escherichia coli
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 32: 183

Liu J, Xu H, Ding P, Lin L (2000)
[Morphological and histological identification and essential oil GC-MS assay of Aralia decaisneana]
Zhong Yao Cai 23: 524

Xu H, Iijima K, Shirakawa T, Shiozawa S, Miwa M, Yamaoka K, Kawamura N, Nakamura H, Yoshikawa N (2000)
Platelet-activating factor acetylhydrolase gene mutation in Japanese children with Escherichia coli O157-associated hemolytic uremic syndrome
Am J Kidney Dis 36: 42

Tanaka R, Iijima K, Xu H, Inoue Y, Murakami R, Shirakawa T, Nishiyama K, Miwa M, Shiozawa S, Nakamura H, Yoshikawa N (1999)
Role of platelet-activating factor acetylhydrolase gene mutation in Japanese childhood IgA nephropathy
Am J Kidney Dis 34: 289

Xu H, Petersen EI, Petersen SB, el-Gewely MR (1999)
Random mutagenesis libraries: optimization and simplification by PCR
Biotechniques 27: 1102

He F, Xu H, Qin F, Xu L, Huang J, He X (1998)
Intermediate myasthenia syndrome following acute organophosphates poisoning--an analysis of 21 cases
Hum Exp Toxicol 17: 40

Xu H, Iijima K, Shiozawa S, Tanaka SS, Inoue Y, Shirakawa T, Nishiyama K, Miwa M, Nakamura H, Yoshikawa N (1998)
Platelet-activating factor acetylhydrolase gene mutation in Japanese nephrotic children
Kidney Int 54: 1867

Yang LR, Xu H, Yao S, Zhu ZQ (1998)
Kinetics of butyl acetate synthesis by lipase-catalyzed transesterification in hexane
Annals of the New York Academy of Sciences 864: 649

Tang XC, Xu H, Feng J, Zhou TX, Liu JS (1994)
Effect of cholinesterase inhibition in vitro by huperzine analogs
Acta Pharmacol Sin 15: 107

Xu H, Tang XC (1987)
[Cholinesterase inhibition by huperzine B]
Acta Pharmacol Sin 8: 18