Bracke A, Van Elzen R, Van der Veken P, Augustyns K, De Meester I, Lambeir AM (2019)
The development and validation of a combined kinetic fluorometric activity assay for fibroblast activation protein alpha and prolyl oligopeptidase in plasma
Clinica Chimica Acta 495: 154

Rea D, Van Elzen R, De Winter H, Van Goethem S, Landuyt B, Luyten W, Schoofs L, Van der Veken P, Augustyns K, De Meester I, Fulop V, Lambeir AM (2017)
Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling
Eur Journal of Medicinal Chemistry 139: 482

Van Elzen R, Schoenmakers E, Brandt I, Van der Veken P, Lambeir AM (2017)
Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach
Protein Engineering Des Sel 30: 217

Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm-Helm A, Noortoots A, Anier K, Van Elzen R, Gerard M, Lambeir AM, Rossner S, Morawski M, Zharkovsky A (2016)
Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro
Journal of Cell Science 129: 3792

Kehoe K, Van Elzen R, Verkerk R, Sim Y, Van der Veken P, Lambeir AM, De Meester I (2016)
Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme
Biochimica & Biophysica Acta 1864: 1481

Klimaviciusa L, Jain RK, Jaako K, Van Elzen R, Gerard M, Van der Veken P, Lambeir AM, Zharkovsky A (2012)
In situ prolyl oligopeptidase activity assay in neural cell cultures
Journal of Neuroscience Methodsods 204: 104

Myohanen TT, Hannula MJ, Van Elzen R, Gerard M, Van der Veken P, Garcia-Horsman JA, Baekelandt V, Mannisto PT, Lambeir AM (2012)
A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease
British Journal of Pharmacology 166: 1097

Van der Veken P, Fulop V, Rea D, Gerard M, Van Elzen R, Joossens J, Cheng JD, Baekelandt V, De Meester I, Lambeir AM, Augustyns K (2012)
P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy
Journal of Medicinal Chemistry 55: 9856

Van Elzen R, Lambeir AM (2011)
Structure and function relationship in prolyl oligopeptidase
CNS Neurol Disord Drug Targets 10: 297