Song W, Beigneux AP, Winther AL, Kristensen KK, Gronnemose AL, Yang Y, Tu Y, Munguia P, Morales J, Jung H, de Jong PJ, Jung CJ, Miyashita K, Kimura T, Nakajima K, Murakami M, Birrane G, Jiang H, Tontonoz P, Ploug M, Fong LG, Young SG (2022)
Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells
J Clinical Investigation 132:
Guo F, Seldin M, Peterfy M, Charugundla S, Zhou Z, Lee SD, Mouton A, Rajbhandari P, Zhang W, Pellegrini M, Tontonoz P, Lusis AJ, Shih DM (2021)
NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
Sci Rep 11: 16409
Ichu TA, Reed A, Ogasawara D, Ulanovskaya O, Roberts A, Aguirre CA, Bar-Peled L, Gao J, Germain J, Barbas S, Masuda K, Conti B, Tontonoz P, Cravatt BF (2020)
ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease
Biochemistry
Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charriere S, Fong LG, Nakajima K, Young SG (2017)
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia
N Engl J Med 376: 1647
Goulbourne CN, Gin P, Tatar A, Nobumori C, Hoenger A, Jiang H, Grovenor CR, Adeyo O, Esko JD, Goldberg IJ, Reue K, Tontonoz P, Bensadoun A, Beigneux AP, Young SG, Fong LG (2014)
The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries
Cell Metab 19: 849
Weinstein MM, Goulbourne CN, Davies BS, Tu Y, Barnes RH, 2nd, Watkins SM, Davis R, Reue K, Tontonoz P, Beigneux AP, Fong LG, Young SG (2012)
Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice
Arterioscler Thromb Vasc Biol 32: 230
Young SG, Davies BS, Voss CV, Gin P, Weinstein MM, Tontonoz P, Reue K, Bensadoun A, Fong LG, Beigneux AP (2011)
GPIHBP1, an endothelial cell transporter for lipoprotein lipase
J Lipid Res 52: 1869
Weinstein MM, Tu Y, Beigneux AP, Davies BS, Gin P, Voss C, Walzem RL, Reue K, Tontonoz P, Bensadoun A, Fong LG, Young SG (2010)
Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice
Arterioscler Thromb Vasc Biol 30: 2106
Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG (2008)
The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma
Mol Endocrinol 22: 2496