Talley TT, Chao CK, Berkman CE, Richardson RJ, Thompson CM (2020)
Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p-Nitrophenyl Leaving Groups
Chemical Research in Toxicology 33: 2455

Bobango J, Wensel S, Hunt J, Amerhamzeh J, Estep K, Talley TT (2015)
Poster: Engineered acetylcholine binding proteins to explore ligand recognition and specificity
Biochemical Pharmacology 97: 627

Bobango J, Denton TT, Talley TT (2015)
Poster: A survey of high resolution AChBP X-ray structures reveals details of tertiary and quaternary movements of the protein, both real and imagined, upon ligand binding
Biochemical Pharmacology 97: 628

Grimster NP, Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz A, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV (2012)
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template
Journal of the American Chemical Society 134: 6732

Rojsanga P, Boonyarat C, Utsintong M, Nemecz A, Yamauchi JG, Talley TT, Olson AJ, Matsumoto K, Vajragupta O (2012)
The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor
Life Sciences 91: 107

Utsintong M, Rojsanga P, Ho KY, Talley TT, Olson AJ, Matsumoto K, Vajragupta O (2012)
Virtual screening against acetylcholine binding protein
J Biomol Screen 17: 204

Yamauchi JG, Gomez K, Grimster N, Dufouil M, Nemecz A, Fotsing JR, Ho KY, Talley TT, Sharpless KB, Fokin VV, Taylor P (2012)
Synthesis of selective agonists for the alpha7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates
Molecular Pharmacology 82: 687

Kombo DC, Mazurov A, Tallapragada K, Hammond PS, Chewning J, Hauser TA, Vasquez-Valdivieso M, Yohannes D, Talley TT, Taylor P, Caldwell WS (2011)
Docking studies of benzylidene anabaseine interactions with alpha7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related alpha7 selective ligands
Eur Journal of Medicinal Chemistry 46: 5625

Talley TT, Nemecz A, Yamauchi JG, Wu J, Ho KY, Sankaran B, Taylor P (2011)
Poster: Acetylcholine binding protein-nicotinic receptor chimeras for delineating structure and determinants of ligand selectivity
Biochemical Pharmacology 82: 1028

Yamauchi JG, Nemecz A, Nguyen QT, Muller A, Schroeder LF, Talley TT, Lindstrom JM, Kleinfeld D, Taylor P (2011)
Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors
PLoS ONE 6: e16519

Bourne Y, Radic Z, Araoz R, Talley TT, Benoit E, Servent D, Taylor P, Molgo J, Marchot P (2010)
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
Proc Natl Acad Sci U S A 107: 6076

Babakhani A, Talley TT, Taylor P, McCammon JA (2009)
A virtual screening study of the acetylcholine binding protein using a relaxed-complex approach
Comput Biol Chem 33: 160

Hibbs RE, Sulzenbacher G, Shi J, Talley TT, Conrod S, Kem WR, Taylor P, Marchot P, Bourne Y (2009)
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor
EMBO Journal 28: 3040

Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, Schork NJ, O'Connor DT, Taylor P (2009)
Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs
Journal of Pharmacology & Experimental Therapeutics 331: 419

Tomizawa M, Talley TT, Park JF, Maltby D, Medzihradszky KF, Durkin KA, Cornejo-Bravo JM, Burlingame AL, Casida JE, Taylor P (2009)
Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling
Journal of Medicinal Chemistry 52: 3735

Talley TT, Harel M, Hibbs RE, Radic Z, Tomizawa M, Casida JE, Taylor P (2008)
Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore
Proc Natl Acad Sci U S A 105: 7606

Taylor P, Talley TT, Radic Z, Hansen SB, Hibbs RE, Shi J (2007)
Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes
Biochemical Pharmacology 74: 1164

Tomizawa M, Maltby D, Medzihradszky KF, Zhang N, Durkin KA, Presley J, Talley TT, Taylor P, Burlingame AL, Casida JE (2007)
Defining nicotinic agonist binding surfaces through photoaffinity labeling
Biochemistry 46: 8798

Tomizawa M, Talley TT, Maltby D, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE (2007)
Mapping the elusive neonicotinoid binding site
Proc Natl Acad Sci U S A 104: 9075

Bourne Y, Hansen SB, Sulzenbacher G, Talley TT, Huxford T, Taylor P, Marchot P (2006)
Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein
Journal of Molecular Neuroscience 30: 103

Hibbs RE, Talley TT, Taylor P (2004)
Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein
Journal of Biological Chemistry 279: 28483

Taylor P, Hansen SB, Talley TT, Hibbs RE, Radic Z (2004)
Contemporary paradigms for cholinergic ligand design guided by biological structure
Bioorganic & Medicinal Chemistry Lett 14: 1875

Gao F, Bern N, Little A, Wang HL, Hansen SB, Talley TT, Taylor P, Sine SM (2003)
Curariform antagonists bind in different orientations to acetylcholine-binding protein
Journal of Biological Chemistry 278: 23020

Hansen SB, Radic Z, Talley TT, Molles BE, Deerinck TJ, Tsigelny I, Taylor P (2002)
Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein
Journal of Biological Chemistry 277: 41299

Doorn JA, Talley TT, Thompson CM, Richardson RJ (2001)
Probing the active sites of butyrylcholinesterase and cholesterol esterase with isomalathion: conserved stereoselective inactivation of serine hydrolases structurally related to acetylcholinesterase
Chemical Research in Toxicology 14: 807

Doorn JA, Schall M, Gage DA, Talley TT, Thompson CM, Richardson RJ (2001)
Identification of Butyrylcholinesterase Adducts after Inhibition with Isomalathion Using Mass Spectrometry: Difference in Mechanism between (1R)- and (1S)-Stereoisomers
Toxicol Appl Pharmacol 176: 73

Doorn JA, Gage DA, Schall M, Talley TT, Thompson CM, Richardson RJ (2000)
Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group
Chemical Research in Toxicology 13: 1313

Jianmongkol S, Marable BR, Berkman CE, Talley TT, Thompson CM, Richardson RJ (1999)
Kinetic Evidence for Different Mechanisms of Acetylcholinesterase Inhibition by (1R)- and (1S)-Stereoisomers of Isomalathion
Toxicol Appl Pharmacol 155: 43

Talley TT, Jianmongkol S, Richardson RJ, Radic Z, Thompson CM (1998)
Isomalathion Stereoisomers
In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.: 531