Xue L, Hou S, Tong M, Fang L, Chen X, Jin Z, Tai HH, Zheng F, Zhan CG (2013)
Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine
Biochemical Journal 453: 447

Xue L, Ko MC, Tong M, Yang W, Hou S, Fang L, Liu J, Zheng F, Woods JH, Tai HH, Zhan CG (2011)
Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine
Molecular Pharmacology 79: 290

Yang W, Pan Y, Zheng F, Cho H, Tai HH, Zhan CG (2009)
Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase
Biophysical Journal 96: 1931

Zheng F, Yang W, Ko MC, Liu J, Cho H, Gao D, Tong M, Tai HH, Woods JH, Zhan CG (2008)
Most efficient cocaine hydrolase designed by virtual screening of transition states
Journal of the American Chemical Society 130: 12148

Gao D, Cho H, Yang W, Pan Y, Yang G, Tai HH, Zhan CG (2006)
Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation
Angew Chem Int Ed Engl 45: 653

Hamza A, Cho H, Tai HH, Zhan CG (2005)
Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants
J Phys Chem B 109: 4776

Pan Y, Gao D, Yang W, Cho H, Yang G, Tai HH, Zhan CG (2005)
Computational redesign of human butyrylcholinesterase for anticocaine medication
Proc Natl Acad Sci U S A 102: 16656