Houngbedji NH, Stepankova S, Pflegr V, Svrckova K, Svarcova M, Vinsova J, Kratky M (2023)
Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study
Pharmaceuticals (Basel) 16:

Kratky M, Novackova K, Svrckova K, Svarcova M, Stepankova S (2023)
New 3-amino-2-thioxothiazolidin-4-one-based inhibitors of acetyl- and butyryl-cholinesterase: synthesis and activity
Future Med Chem

Sachleviciute U, Gonzalez G, Kvasnicova M, Stepankova S, Kleizien N, Bieliauskas A, Zatloukal M, Strnad M, Slok FA, Kvasnica M, Sackus A, zukauskait A (2023)
Synthesis and neuroprotective activity of 3-aryl-3-azetidinyl acetic acid methyl ester derivatives
Arch Pharm (Weinheim)

Gonzalez G, Kvasnica M, Svrckova K, Stepankova S, Santos JRC, Perina M, Jorda R, Lopes SMM, Melo T (2022)
Ring-fused 3beta-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties
J Steroid Biochem Mol Biol

Pflegr V, Stepankova S, Svrckova K, Svarcova M, Vinsova J, Kratky M (2022)
5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study
Pharmaceuticals (Basel) 15: 400

Kos J, Kozik V, Pindjakova D, Jankech T, Smolinski A, Stepankova S, Hosek J, Oravec M, Jampilek J, Bak A (2021)
Synthesis and Hybrid SAR Property Modeling of Novel Cholinesterase Inhibitors
Int J Mol Sci 22:

Kratky M, Vu QA, Stepankova S, Maruca A, Silva TB, Ambroz M, Pflegr V, Rocca R, Svrckova K, Alcaro S, Borges F, Vinsova J (2021)
Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study
Bioorg Chem 116: 105301

Kratky M, Stepankova S, Konecna K, Svrckova K, Maixnerova J, Svarcova M, Janourek O, Trejtnar F, Vinsova J (2021)
Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors
Pharmaceuticals (Basel) 14:

Magar P, Parravicini O, Stepankova S, Svrckova K, Garro AD, Jendrzejewska I, Pauk K, Hosek J, Jampilek J, Enriz RD, Imramovsky A (2021)
Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE
Int J Mol Sci 22:

Kielczewska U, Jorda R, Gonzalez G, Morzycki JW, Ajani H, Svrckova K, Stepankova S, Wojtkielewicz A (2020)
The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring
J Steroid Biochem Mol Biol

Kratky M, Baranyai Z, Stepankova S, Svrckova K, Svarcova M, Stolarikova J, Horvath L, Bosze S, Vinsova J (2020)
N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity
Molecules 25:

Kratky M, Jaklova K, Stepankova S, Svrckova K, Pflegr V, Vinsova J (2020)
N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors
Curr Top Med Chem 20: 2094

Kratky M, Stepankova S, Brablikova M, Svrckova K, Svarcova M, Vinsova J (2020)
Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors
Curr Top Med Chem 20: 2106

Bak A, Kozik V, Kozakiewicz D, Gajcy K, Strub DJ, Swietlicka A, Stepankova S, Imramovsky A, Polanski J, Smolinski A, Jampilek J (2019)
Novel Benzene-Based Carbamates for AChE/BChE Inhibition: Synthesis and Ligand/Structure-Oriented SAR Study
Int J Mol Sci 20: 1524

Chlebek J, Korabecny J, Dolezal R, Stepankova S, Perez DI, Hostalkova A, Opletal L, Cahlikova L, Macakova K, Kucera T, Hrabinova M, Jun D (2019)
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier
Molecules 24:

Kratky M, Stepankova S, Houngbedji NH, Vosatka R, Vorcakova K, Vinsova J (2019)
2-Hydroxy-N-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase
Biomolecules 9:

Kratky M, Stepankova S, Vorcakova K, Vinsova J (2018)
Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase
Bioorg Chem 80: 668

Vorcakova K, Majekova M, Horakova E, Drabina P, Sedlak M, Stepankova S (2018)
Synthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking
Bioorg Chem 78: 280

Kratky M, Stepankova S, Vorcakova K, Navratilova L, Trejtnar F, Stolarikova J, Vinsova J (2017)
Synthesis of readily available fluorophenylalanine derivatives and investigation of their biological activity
Bioorg Chem 71: 244

Pizova H, Havelkova M, Stepankova S, Bak A, Kauerova T, Kozik V, Oravec M, Imramovsky A, Kollar P, Bobal P, Jampilek J (2017)
Proline-Based Carbamates as Cholinesterase Inhibitors
Molecules 22:

Horakova E, Drabina P, Broz B, Stepankova S, Vorcakova K, Kralovec K, Havelek R, Sedlak M (2016)
Synthesis, characterization and in vitro evaluation of substituted N-(2-phenylcyclopropyl)carbamates as acetyl- and butyrylcholinesterase inhibitors
J Enzyme Inhib Med Chem

Kratky M, Stepankova S, Vorcakova K, Svarcova M, Vinsova J (2016)
Novel Cholinesterase Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates
Molecules 21:

Kratky M, Stepankova S, Vorcakova K, Vinsova J (2016)
Synthesis and in vitro evaluation of novel rhodanine derivatives as potential cholinesterase inhibitors
Bioorg Chem 68: 23

Pejchal V, Stepankova S, Pejchalova M, Kralovec K, Havelek R, Ruzickova Z, Ajani H, Lo R, Lepsik M (2016)
Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors
Bioorganic & Medicinal Chemistry 24: 1560

Stepankova S, Vorcakova K (2016)
Cholinesterase-based biosensors
J Enzyme Inhib Med Chem

Cahlikova L, Perez DI, Stepankova S, Chlebek J, Safratova M, Host'alkova A, Opletal L (2015)
In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier
Journal of Natural Products 78: 1189

Havlasova J, Safratova M, Siatka T, Stepankova S, Novak Z, Locarek M, Opletal L, Hrabinova M, Jun D, Benesova N, Kunes J, Cahlikova L (2014)
Chemical composition of bioactive alkaloid extracts from some Narcissus species and varieties and their biological activity
Nat Prod Commun 9: 1151

Kratky M, Stepankova S, Vorcakova K, Vinsova J (2014)
Salicylanilide diethyl phosphates as cholinesterases inhibitors
Bioorg Chem 58C: 48

Vinsova J, Kratky M, Komloova M, Dadapeer E, Stepankova S, Vorcakova K, Stolarikova J (2014)
Diethyl 2-(Phenylcarbamoyl)phenyl Phosphorothioates: Synthesis, Antimycobacterial Activity and Cholinesterase Inhibition
Molecules 19: 7152

Imramovsky A, Pejchal V, Stepankova S, Vorcakova K, Jampilek J, Vanco J, Simunek P, Kralovec K, Bruckova L, Mandikova J, Trejtnar F (2013)
Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors
Bioorganic & Medicinal Chemistry 21: 1735

Kovarova M, Komers K, Stepankova S, Parik P, Cegan A (2013)
New method for the determination of the half inhibition concentration (IC50) of cholinesterase inhibitors
Z Naturforsch C 68: 133

Imramovsky A, Stepankova S, Vanco J, Pauk K, Monreal-Ferriz J, Vinsova J, Jampilek J (2012)
Acetylcholinesterase-inhibiting activity of salicylanilide N-alkylcarbamates and their molecular docking
Molecules 17: 10142

Pejchal V, Stepankova S, Padelkova Z, Imramovsky A, Jampilek J (2011)
1,3-substituted imidazolidine-2,4,5-triones: synthesis and inhibition of cholinergic enzymes
Molecules 16: 7565

Kovarova M, Komers K, Stepankova S, Cegan A (2010)
Inhibition of acetylcholinesterase by 14 achiral and five chiral imidazole derivates
Bioresour Technol 101: 6281

Komersova A, Masopustova M, Komers K, Stepankova S, Cegan A (2007)
In vitro inhibition of cholinesterases by carbamates--a kinetic study
Z Naturforsch C 62: 305

Stepankova S, Komers K, Komersova A, Masopustova M, Cegan A (2007)
Inhibition of cholinesterase by dialkylcarbamates
Z Naturforsch C 62: 308

Zdrazilova P, Stepankova S, Komersova A, Vranova M, Komers K, Cegan A (2006)
Kinetics of 13 new cholinesterase inhibitors
Z Naturforsch C 61: 611

Zdrazilova P, Stepankova S, Vranova M, Komers K, Komersova A, Cegan A (2006)
Kinetics of total enzymatic hydrolysis of acetylcholine and acetylthiocholine
Z Naturforsch C 61: 289

Stepankova S, Vranova M, Zdrazilova P, Komers K, Komersova A, Cegan A (2005)
Two new methods monitoring kinetics of hydrolysis of acetylcholine and acetylthiocholine
Z Naturforsch C 60: 943

Zdrazilova P, Stepankova S, Komers K, Ventura K, Cegan A (2004)
Half-inhibition concentrations of new cholinesterase inhibitors
Z Naturforsch C 59: 293