Pehar V, Kolic D, Zandona A, Sinko G, Katalinic M, Stepanic V, Kovarik Z (2023)
Selected herbicides screened for toxicity and analysed as inhibitors of both cholinesterases
Chemico-Biological Interactions 379: 110506

Sinko G (2023)
Modeling of a near-attack conformation of oxime in phosphorylated acetylcholinesterase via a reactivation product, a phosphorylated oxime
Chemico-Biological Interactions

Milicevic A, Sinko G (2022)
Use of connectivity index and simple topological parameters for estimating the inhibition potency of acetylcholinesterase
Saudi Pharm J 30: 369

Milicevic A, Sinko G (2022)
Evaluation of the Key Structural Features of Various Butyrylcholinesterase Inhibitors Using Simple Molecular Descriptors
Molecules 27:

Cadez T, Kolic D, Sinko G, Kovarik Z (2021)
Assessment of four organophosphorus pesticides as inhibitors of human acetylcholinesterase and butyrylcholinesterase
Sci Rep 11: 21486

Bosak A, Bavec A, Konte T, Sinko G, Kovarik Z, Golicnik M (2020)
Interactions of Paraoxonase-1 with Pharmacologically Relevant Carbamates
Molecules 25:

Marakovic N, Knezevic A, Roncevic I, Brazzolotto X, Kovarik Z, Sinko G (2020)
Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases
Biochemical Journal 477: 2771

Zandona A, Katalinic M, Sinko G, Radman Kastelic A, Primozic I, Kovarik Z (2020)
Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers
Archives of Toxicology 94: 3157

Baumann K, Kordic L, Mocibob M, Sinko G, Tomic S (2019)
Synthesis and In Vitro Screening of Novel Heterocyclic beta-d-Gluco- and beta-d-Galactoconjugates as Butyrylcholinesterase Inhibitors
Molecules 24:

Bosak A, Opsenica DM, Sinko G, Zlatar M, Kovarik Z (2019)
Structural aspects of 4-aminoquinolines as reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase
Chemico-Biological Interactions 308: 101

Macek Hrvat N, Kalisiak J, Sinko G, Radic Z, Sharpless KB, Taylor P, Kovarik Z (2019)
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Toxicol Lett 321: 83

Sinko G (2019)
Assessment of scoring functions and in silico parameters for AChE-ligand interactions as a tool for predicting inhibition potency
Chemico-Biological Interactions 308: 216

Katalinic M, Sinko G, Macek Hrvat N, Zorbaz T, Bosak A, Kovarik Z (2018)
Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations
Toxicology 406-407: 104

Macek Hrvat N, Zorbaz T, Sinko G, Kovarik Z (2018)
The estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation
Toxicol Lett 293: 222

Bosak A, Knezevic A, Gazic Smilovic I, Sinko G, Kovarik Z (2017)
Resorcinol-, catechol- and saligenin-based bronchodilating beta2-agonists as inhibitors of human cholinesterase activity
J Enzyme Inhib Med Chem 32: 789

Marakovic N, Sinko G (2017)
The Lock is the Key: Development of Novel Drugs through Receptor Based Combinatorial Chemistry
Acta Chim Slov 64: 15

Busic V, Katalinic M, Sinko G, Kovarik Z, Gaso-Sokac D (2016)
Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds
Toxicol Lett 262: 114

Marakovic N, Knezevic A, Vinkovic V, Kovarik Z, Sinko G (2016)
Design and synthesis of N-substituted-2-hydroxyiminoacetamides and interactions with cholinesterases
Chemico-Biological Interactions 259: 122

Ulm L, Krivohlavek A, Jurasin D, Ljubojevic M, Sinko G, Crnkovic T, Zuntar I, Sikic S, Vinkovic Vrcek I (2015)
Response of biochemical biomarkers in the aquatic crustacean Daphnia magna exposed to silver nanoparticles
Environ Sci Pollut Res Int 22: 19990

Sinko G, Vinkovic Vrcek I, Goessler W, Leitinger G, Dijanosic A, Miljanic S (2014)
Alteration of cholinesterase activity as possible mechanism of silver nanoparticle toxicity
Environ Sci Pollut Res Int 21: 1391

Bosak A, Smilovic IG, Stimac A, Vinkovic V, Sinko G, Kovarik Z (2013)
Peripheral site and acyl pocket define selective inhibition of mouse butyrylcholinesterase by two biscarbamates
Archives of Biochemistry & Biophysics 529: 140

Bosak A, Gazic Smilovic I, Sinko G, Vinkovic V, Kovarik Z (2012)
Metaproterenol, isoproterenol, and their bisdimethylcarbamate derivatives as human cholinesterase inhibitors
Journal of Medicinal Chemistry 55: 6716

Sinko G, Kovarik Z, Reiner E, Simeon-Rudolf V, Stojan J (2011)
Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers
Biochimie 93: 1797

Katalinic M, Rusak G, Domacinovic Barovic J, Sinko G, Jelic D, Antolovic R, Kovarik Z (2010)
Structural aspects of flavonoids as inhibitors of human butyrylcholinesterase
Eur Journal of Medicinal Chemistry 45: 186

Kovarik Z, Katalinic M, Sinko G, Binder J, Holas O, Jung YS, Musilova L, Jun D, Kuca K (2010)
Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase
Chemico-Biological Interactions 187: 167

Sinko G, Brglez J, Kovarik Z (2010)
Interactions of pyridinium oximes with acetylcholinesterase
Chemico-Biological Interactions 187: 172

Gazic I, Bosak A, Sinko G, Vinkovic V, Kovarik Z (2008)
Preparative HPLC separation of bambuterol enantiomers and stereoselective inhibition of human cholinesterases
Anal Bioanal Chem 385: 1513

Kovarik Z, Calic M, Sinko G, Bosak A, Berend S, Vrdoljak AL, Radic B (2008)
Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning
Chemico-Biological Interactions 175: 173

Kovarik Z, Calic M, Sinko G, Bosak A (2007)
Structure-activity approach in the reactivation of tabun-phosphorylated human acetylcholinesterase with bispyridinium para-aldoximes
Arh Hig Rada Toksikol 58: 201

Sinko G, Calic M, Bosak A, Kovarik Z (2007)
Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes
Analytical Biochemistry 370: 223

Sinko G, Calic M, Kovarik Z (2006)
para- and ortho-Pyridinium aldoximes in reaction with acetylthiocholine
FEBS Letters 580: 3167

Sinko G, Bosak A, Kovarik Z, Simeon-Rudolf V (2005)
Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups
Chemico-Biological Interactions 157-158: 421

Reiner E, Sinko G, Stuglin A, Simeon-Rudolf V (2004)
Peripheral binding of ethopropazine to horse serum butyrylcholinesterase.
Cholinergic Mechanisms, CRC Press

Reiner E, Sinko G, Radic Z, Taylor P, Simeon-Rudolf V (2004)
Kinetics of interaction of ethopropazine enantiomers with butyrylcholinesterase and acetylcholinesterase.
Cholinergic Mechanisms, CRC Press

Reiner E, Sinko G, Bosak A, Simeon-Rudolf V, Radic Z, Taylor P, Stojan J, Golicnik M (2004)
Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 187

Reiner E, Sinko G, Stuglin A, Simeon-Rudolf V, Radic Z, Taylor P, Stojan J, Golicnik M (2004)
Poster (19) Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine.
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 330

Simeon-Rudolf V, Sinko G, Stuglin A, Stojan J, Golicnik M (2004)
Comparison of two reaction schemes for the hydrolysis of acetylthiocholine by butyrylcholinesterase.
Cholinergic Mechanisms, CRC Press

Eyer P, Worek F, Kiderlen D, Sinko G, Stuglin A, Simeon-Rudolf V, Reiner E (2003)
Molar absorption coefficients for the reduced Ellman reagent: reassessment
Analytical Biochemistry 312: 224

Golicnik M, Sinko G, Simeon-Rudolf V, Grubic Z, Stojan J (2002)
Kinetic Model of Ethopropazine Interaction with Horse Serum Butyrylcholinesterase and Its Docking into the Active Site
Archives of Biochemistry & Biophysics 398: 23

Reiner E, Sinko G, Skrinjaric-Spoljar M, Simeon-Rudolf V (2000)
Comparison of protocols for measuring activities of human blood cholinesterases by the Ellman method
Arh Hig Rada Toksikol 51: 13