Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Grishchenko MV, Lushchekina SV, Astakhova TY, Serebryakova OG, Timokhina EN, Zhilina EF, Shchegolkov EV, Ulitko MV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ (2023) <br />Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease<br /><i>Int J Mol Sci</i> <b>24</b>: 2285<br /><br />Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Timokhina EN, Serebryakova OG, Shchepochkin AV, Averkov MA, Utepova IA, Demina NS, Radchenko EV, Palyulin VA, Fisenko VP, Bachurin SO, Chupakhin ON, Charushin VN, Richardson RJ (2023) <br />Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit beta-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease<br /><i>Front Pharmacol</i> <b>14</b>: 1219980<br /><br />Burgart YV, Elkina NA, Shchegolkov EV, Krasnykh OP, Makhaeva GF, Triandafilova GA, Solodnikov SY, Boltneva NP, Rudakova EV, Kovaleva NV, Serebryakova OG, Ulitko MV, Borisevich SS, Gerasimova NA, Evstigneeva NP, Kozlov SA, Korolkova YV, Minin AS, Belousova AV, Mozhaitsev ES, Klabukov AM, Saloutin VI (2022) <br />Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals<br /><i>Molecules</i> <b>28</b>: <br /><br />Grishchenko MV, Makhaeva GF, Burgart YV, Rudakova EV, Boltneva NP, Kovaleva NV, Serebryakova OG, Lushchekina SV, Astakhova TY, Zhilina EF, Shchegolkov EV, Richardson RJ, Saloutin VI (2022) <br />Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease<br /><i>ChemMedChem</i> <br /><br />Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Kovaleva NV, Rudakova EV, Elkina NA, Shchegolkov EV, Burgart YV, Stupina TS, Terentiev AA, Radchenko EV, Palyulin VA, Saloutin VI, Bachurin SO, Richardson RJ (2021) <br />Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold<br /><i>Eur Journal of Medicinal Chemistry</i> <b>218</b>: 113385<br /><br />Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korabecny J, Soukup O, Richardson RJ (2021) <br />Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment<br /><i>Bioorg Chem</i> <b>112</b>: 104974<br /><br />Akimov MG, Kudryavtsev DS, Kryukova EV, Fomina-Ageeva EV, Zakharov SS, Gretskaya NM, Zinchenko GN, Serkov IV, Makhaeva GF, Boltneva NP, Kovaleva NV, Serebryakova OG, Lushchekina SV, Palikov VA, Palikova Y, Dyachenko IA, Kasheverov IE, Tsetlin VI, Bezuglov VV (2020) <br />Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System<br /><i>Biomolecules</i> <b>10</b>: <br /><br />Khudina OG, Makhaeva GF, Elkina NA, Boltneva NP, Serebryakova OG, Shchegolkov EV, Rudakova EV, Lushchekina SV, Burgart YV, Bachurin SO, Richardson RJ, Saloutin VI (2019) <br />Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <br /><br />Makhaeva GF, Elkina NA, Shchegolkov EV, Boltneva NP, Lushchekina SV, Serebryakova OG, Rudakova EV, Kovaleva NV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ (2019) <br />Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors<br /><i>Bioorg Chem</i> <b>91</b>: 103097<br /><br />Makhaeva GF, Boltneva NP, Lushchekina SV, Rudakova EV, Serebryakova OG, Kulikova LN, Beloglazkin AA, Borisov RS, Richardson RJ (2018) <br />Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics<br /><i>Bioorganic & Medicinal Chemistry</i> <b>26</b>: 4716<br /><br />Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Rudakova EV, Ustyugov AA, Bachurin SO, Shchepochkin AV, Chupakhin ON, Charushin VN, Richardson RJ (2017) <br />9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment<br /><i>Bioorganic & Medicinal Chemistry</i> <b>25</b>: 5981<br /><br />Shchegol'kov EV, Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Rudakova EV, Kovaleva NV, Burgart YV, Saloutin VI, Chupakhin ON, Bachurin SO, Richardson RJ (2017) <br />Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors<br /><i>Bioorganic & Medicinal Chemistry</i> <b>25</b>: 3997<br /><br />Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Bachurin SO, Richardson RJ (2016) <br />Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors<br /><i>Bioorganic & Medicinal Chemistry</i> <b>24</b>: 1050<br /><br />Makhaeva GF, Rudakova EV, Serebryakova OG, Aksinenko AY, Lushchekina SV, Bachurin SO, Richardson RJ (2016) <br />Esterase profiles of organophosphorus compounds in vitro predict their behavior in vivo<br /><i>Chemico-Biological Interactions</i> <b>259</b>: 332<br /><br />Makhaeva GF, Lushchekina SV, Boltneva NP, Sokolov VB, Grigoriev VV, Serebryakova OG, Vikhareva EA, Aksinenko AY, Barreto GE, Aliev G, Bachurin SO (2015) <br />Conjugates of gamma-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease<br /><i>Sci Rep</i> <b>5</b>: 13164<br /><br />Makhaeva GF, Rudakova EV, Hein ND, Serebryakova OG, Kovaleva NV, Boltneva NP, Fink JK, Richardson RJ (2014) <br />Further studies toward a mouse model for biochemical assessment of neuropathic potential of organophosphorus compounds<br /><i>J Appl Toxicol</i> <b>34</b>: 1426<br /><br />Boltneva NP, Serebryakova OG, Makhaeva GF, Serkov IV, Proshin AN, Bachurin SO (2013) <br />N,N-disubstituted 2-aminothiazolines as new inhibitors of serine esterases<br /><i>Dokl Biochem Biophys</i> <b>451</b>: 209<br /><br />Makhaeva GF, Lushchekina SV, Serebryakova OG, Aksinenko AY, Goreva TV, Richardson RJ, Martynov IV (2013) <br />Kinetics and mechanism of inhibition of serine esterases by fluorinated carbethoxy 1-aminophosphonates<br /><i>Dokl Biochem Biophys</i> <b>451</b>: 203<br /><br />Sokolova NV, Nenajdenko VG, Sokolov VB, Serebryakova OG, Makhaeva GF (2011) <br />Synthesis and testing of trifluoromethyl-containing phosphonate-peptide conjugates as inhibitors of serine hydrolases<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>21</b>: 7216<br /><br />Makhaeva GF, Aksinenko AY, Sokolov VB, Serebryakova OG, Richardson RJ (2009) <br />Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>19</b>: 5528<br /><br />Makhaeva GF, Serebryakova OG, Boltneva NP, Galenko TG, Aksinenko AY, Sokolov VB, Martynov IV (2008) <br />Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols<br /><i>Dokl Biochem Biophys</i> <b>423</b>: 352<br /><br />