Brenner T, Hamra-Amitay Y, Evron T, Boneva N, Seidman S, Soreq H (2003)
The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis
FASEB Journal 17: 214
Cohen O, Erb C, Ginzberg D, Pollak Y, Seidman S, Shoham S, Yirmiya R, Soreq H (2002)
Neuronal overexpression of 'readthrough' acetylcholinesterase is associated with antisense-suppressible behavioral impairments
Mol Psychiatry 7: 874
Galyam N, Grisaru D, Grifman M, Melamed-Book N, Eckstein F, Seidman S, Eldor A, Soreq H (2001)
Complex host cell responses to antisense suppression of ACHE gene expression
Antisense Nucleic Acid Drug Dev 11: 51
Mor I, Grisaru D, Titelbaum L, Evron T, Richler C, Wahrman J, Sternfeld M, Yogev L, Meiri N, Seidman S, Soreq H (2001)
Modified testicular expression of stress-associated readthrough acetylcholinesterase predicts male infertility
FASEB Journal 15: 2039
Soreq H, Seidman S (2001)
Acetylcholinesterase--new roles for an old actor
Nat Rev Neurosci 2: 294
Lev-Lehman E, Evron T, Broide RS, Meshorer E, Ariel I, Seidman S, Soreq H (2000)
Synaptogenesis and myopathy under acetylcholinesterase overexpression
Journal of Molecular Neuroscience 14: 93
Shohami E, Kaufer D, Chen Y, Seidman S, Cohen O, Ginzberg D, Melamed-Book N, Yirmiya R, Soreq H (2000)
Antisense prevention of neuronal damages following head injury in mice
J Mol Med (Berl) 78: 228
Soreq H, Seidman S (2000)
Anti-sense approach to anticholinesterase therapeutics
Isr Med Assoc J 2: 81
Kaufer D, Friedman A, Seidman S, Soreq H (1999)
Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinergic neurotransmission
Chemico-Biological Interactions 119-120: 349
Andres C, Seidman S, Beeri R, Timberg R, Soreq H (1998)
Transgenic acetylcholinesterase induces enlargement of murine neuromuscular junctions but leaves spinal cord synapses intact
Neurochem Int 32: 449
Grifman M, Galyam N, Seidman S, Soreq H (1998)
Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis
Proc Natl Acad Sci U S A 95: 13935
Kaufer D, Friedman A, Seidman S, Soreq H (1998)
Acute stress facilitates long-lasting changes in cholinergic gene expression
Nature 393: 373
Seidman S, Cohen O, Ginzberg D, Eichengreen E, Pollak Y, Yirmiya R, Soreq H (1998)
Multilevel Approaches to AChE-Induced Impairments in Learning and Memory
In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.: 183
Shapira M, Seidman S, Livni N, Soreq H (1998)
In vivo and in vitro resistance to multiple anticholinesterases in Xenopus laevis tadpoles
Toxicol Lett 103: 205
Seidman S, Sternfeld M, Ben-Aziz-Aloya R, Timberg R, Kaufer-Nachum D, Soreq H (1995)
Synaptic and epidermal accumulations of human acetylcholinesterase are encoded by alternative 3'-terminal exons
Molecular & Cellular Biology 15: 2993
Sternfeld M, Seidman S, Ben Aziz-Aloya R, Shapira M, Timberg R, Kaufer D, Soreq H (1995)
Alternative Exon 6 Directs Synaptic Localization of Recombinant Human Acetylcholinesterase in Neuromuscular Junctions of Xenopus laevis Embryos
In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.: 45
Seidman S, Aziz-Aloya RB, Timberg R, Loewenstein Y, Velan B, Shafferman A, Liao J, Norgaard-Pedersen B, Brodbeck U, Soreq H (1994)
Overexpressed monomeric human acetylcholinesterase induces subtle ultrastructural modifications in developing neuromuscular junctions of Xenopus laevis embryos
Journal of Neurochemistry 62: 1670
Shapira M, Seidman S, Sternfeld M, Timberg R, Kaufer D, Patrick J, Soreq H (1994)
Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins
Proceedings of the National Academy of Sciences of the United States of America 91: 9072
Ben-Aziz-Aloya R, Seidman S, Timberg R, Sternfeld M, Zakut H, Soreq H (1993)
Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos
Proceedings of the National Academy of Sciences of the United States of America 90: 2471
Lapidot-Lifson Y, Patinkin D, Prody CA, Ehrlich G, Seidman S, Ben-Aziz R, Benseler F, Eckstein F, Zakut H, Soreq H (1992)
Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis
Proc Natl Acad Sci U S A 89: 579
Neville LF, Gnatt A, Loewenstein Y, Seidman S, Ehrlich G, Soreq H (1992)
Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE
EMBO Journal 11: 1641
Soreq H, Seidman S (1992)
Xenopus oocyte microinjection: from gene to protein.
Methods Enzymol 207: 225
Ben-Aziz R, Gnatt A, Prody C, Lev-Lehman E, Neville LF, Seidman S, Ginzberg D, Soreq H, Lapidot-Lifson Y, Zakut H (1991)
Differential Codon Usage and Distinct Surface Probabilities in Human Acetylcholinesterase and Butyrylcholinesterase
In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC: 172
Dreyfus PA, Pincon-Raymond M, Zakut H, Seidman S, Soreq H (1991)
Search for the Molecular Origins of Butyrylcholinesterase Polymorphism by cDNA Screening, Deletion Mutagenesis, and Xenopus Oocyte Co-Injections
In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC: 162
Neville LF, Gnatt A, Seidman S, Loewenstein Y, Padan R, Soreq H (1991)
Poster: Modified ligand-binding properties of butyrylcholinesterase-muteins produced in microinjected Xenopus oocytes
In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC: 197 198
Velan B, Kronman C, Grosfeld H, Leitner M, Gozes Y, Flashner Y, Sery T, Cohen S, Ben-Aziz R, Seidman S, Shafferman A, Soreq H (1991)
Recombinant human acetylcholinesterase is secreted from transiently transfected 293 cells as a soluble globular enzyme
Cellular Molecular Neurobiology 11: 143
Neville LF, Gnatt A, Padan R, Seidman S, Soreq H (1990)
Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations
Journal of Biological Chemistry 265: 20735
Patinkin D, Seidman S, Eckstein F, Benseler F, Zakut H, Soreq H (1990)
Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro
Molecular & Cellular Biology 10: 6046
Seidman S, Soreq H (1990)
Coinjection of Xenopus oocytes with cDNA-produced and native mRNAs: a molecular biological approach to the tissue-specific processing of human cholinesterases.
International Review of Neurobiology 32: 107
Soreq H, Ben-Aziz R, Prody CA, Seidman S, Gnatt A, Neville LF, Lieman-Hurwitz J, Lev-Lehman E, Ginzberg D, Lipidot-Lifson Y (1990)
Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure
Proceedings of the National Academy of Sciences of the United States of America 87: 9688
Zakut H, Ehrlich G, Ayalon A, Prody CA, Malinger G, Seidman S, Ginzberg D, Kehlenbach R, Soreq H (1990)
Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas
Journal of Clinical Investigation 86: 900
Dreyfus PA, Seidman S, Pincon-Raymond M, Murawsky M, Rieger F, Schejter E, Zakut H, Soreq H (1989)
Tissue-specific processing and polarized compartmentalization of clone-produced cholinesterase in microinjected Xenopus oocytes
Cellular Molecular Neurobiology 9: 323
Soreq H, Seidman S, Dreyfus PA, Zevin-Sonkin D, Zakut H (1989)
Expression and tissue-specific assembly of human butyrylcholine esterase in microinjected Xenopus laevis oocytes
Journal of Biological Chemistry 264: 10608
Dreyfus PA, Zevin-Sonkin D, Seidman S, Prody CA, Zisling R, Zakut H, Soreq H (1988)
Cross-homologies and structural differences between human cholinesterases revealed by antibodies against cDNA-produced human butyrylcholinesterase peptides
Journal of Neurochemistry 51: 1858