Lalut J, Santoni G, Karila D, Lecoutey C, Davis A, Nachon F, Silman I, Sussman JL, Weik M, Maurice T, Dallemagne P, Rochais C (2019) <br />Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase<br /><i>Eur Journal of Medicinal Chemistry</i> <b>162</b>: 234<br /><br />Dolles D, Hoffmann M, Gunesch S, Marinelli O, Moller J, Santoni G, Chatonnet A, Lohse MJ, Wittmann HJ, Strasser A, Nabissi M, Maurice T, Decker M (2018) <br />Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles<br /><i>Journal of Medicinal Chemistry</i> <b>61</b>: 1646<br /><br />Santoni G, de Sousa J, De la Mora E, Dias J, Jean L, Sussman JL, Silman I, Renard PY, Brown RCD, Weik M, Baati R, Nachon F (2018) <br />Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents<br /><i>Journal of Medicinal Chemistry</i> <b>61</b>: 7630<br /><br />Brazzolotto X, Igert A, Guillon V, Santoni G, Nachon F (2017) <br />Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development<br /><i>Molecules</i> <b>22</b>: <br /><br />Kliachyna M, Santoni G, Nussbaum V, Renou J, Sanson B, Colletier JP, Arboleas M, Loiodice M, Weik M, Jean L, Renard PY, Nachon F, Baati R (2014) <br />Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase<br /><i>Eur Journal of Medicinal Chemistry</i> <b>78C</b>: 455<br /><br />Oueis E, Santoni G, Ronco C, Syzgantseva O, Tognetti V, Joubert L, Romieu A, Weik M, Jean L, Sabot C, Nachon F, Renard PY (2014) <br />Reaction site-driven regioselective synthesis of AChE inhibitors<br /><i>Org Biomol Chem</i> <b>12</b>: 156<br /><br />Carletti E, Colletier JP, Schopfer LM, Santoni G, Masson P, Lockridge O, Nachon F, Weik M (2013) <br />Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry<br /><i>Chemical Research in Toxicology</i> <b>26</b>: 280<br /><br />