Javed MA, Jan MS, Shbeer AM, Al-Ghorbani M, Rauf A, Wilairatana P, Mannan A, Sadiq A, Farooq U, Rashid U (2023)
Evaluation of pyrimidine/pyrrolidine-sertraline based hybrids as multitarget anti-Alzheimer agents: In-vitro, in-vivo, and computational studies
Biomed Pharmacother 159: 114239
Javed MA, Bibi S, Jan MS, Ikram M, Zaidi A, Farooq U, Sadiq A, Rashid U (2022)
Diclofenac derivatives as concomitant inhibitors of cholinesterase, monoamine oxidase, cyclooxygenase-2 and 5-lipoxygenase for the treatment of Alzheimer's disease: synthesis, pharmacology, toxicity and docking studies
RSC Adv 12: 22503
Mahnashi MH, Alshahrani MA, Nahari MH, Hassan SSU, Jan MS, Ayaz M, Ullah F, Alshehri OM, Alshehri MA, Rashid U, Sadiq A (2022)
In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer's Disease
Metabolites 12:
Shahid Nadeem M, Azam Khan J, Kazmi I, Rashid U (2022)
Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A/B for the Treatment of Alzheimer Disease
ACS Omega 7: 9369
Waseem W, Anwar F, Saleem U, Ahmad B, Zafar R, Anwar A, Saeed Jan M, Rashid U, Sadiq A, Ismail T (2022)
Prospective Evaluation of an Amide-Based Zinc Scaffold as an Anti-Alzheimer Agent: In Vitro, In Vivo, and Computational Studies
ACS Omega 7: 26723
Javed MA, Ashraf N, Saeed Jan M, Mahnashi MH, Alqahtani YS, Alyami BA, Alqarni AO, Asiri YI, Ikram M, Sadiq A, Rashid U (2021)
Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease
ACS Chem Neurosci
Mahnashi MH, Alyami BA, Alqahtani YS, Alqarni AO, Jan MS, Ayaz M, Ullah F, Shahid M, Rashid U, Sadiq A (2021)
Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches
BMC Complement Med Ther 21: 248
Nadeem MS, Khan JA, Rashid U (2021)
Fluoxetine and sertraline based multitarget inhibitors of cholinesterases and monoamine oxidase-A/B for the treatment of Alzheimer's disease: Synthesis, pharmacology and molecular modeling studies
Int J Biol Macromol 193: 19
Ahmad A, Ullah F, Sadiq A, Ayaz M, Saeed Jan M, Shahid M, Wadood A, Mahmood F, Rashid U, Ullah R, Sahibzada MUK, Alqahtani AS, Mahmood HM (2020)
Comparative Cholinesterase, alpha-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives
Drug Des Devel Ther 14: 2165
Amin MJ, Miana GA, Rashid U, Miraz Rahman K, Khan HU, Sadiq A (2020)
SAR based in-vitro anticholinesterase and molecular docking studies of nitrogenous progesterone derivatives
Steroids
Uddin N, Ali N, Uddin Z, Nazir N, Zahoor M, Rashid U, Ullah R, Alqahtani AS, Alqahtani AM, Nasr FA, Liu M, Nisar M (2020)
Evaluation of Cholinesterase Inhibitory Potential of Different Genotypes of Ziziphus nummularia, Their HPLC-UV, and Molecular Docking Analysis
Molecules 25: 5011
Ahmad G, Rasool N, Rizwan K, Imran I, Zahoor AF, Zubair M, Sadiq A, Rashid U (2019)
Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs
Bioorg Chem 92: 103216
Ahmad A, Ullah F, Sadiq A, Ayaz M, Rahim H, Rashid U, Ahmad S, Jan MS, Ullah R, Shahat AA, Mahmood HM (2019)
Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies
Drug Des Devel Ther 13: 4185
Sadiq A, Zeb A, Ullah F, Ahmad S, Ayaz M, Rashid U, Muhammad N (2018)
Chemical Characterization, Analgesic, Antioxidant, and Anticholinesterase Potentials of Essential Oils From Isodon rugosus Wall. ex. Benth
Front Pharmacol 9: 623
Tanoli ST, Ramzan M, Hassan A, Sadiq A, Jan MS, Khan FA, Ullah F, Ahmad H, Bibi M, Mahmood T, Rashid U (2018)
Design, synthesis and bioevaluation of tricyclic fused ring system as dual binding site acetylcholinesterase inhibitors
Bioorg Chem 83: 336
Virk NA, Rehman A, Abbasi MA, Siddiqui SZ, Rashid U, Iqbal J, Saleem M, Ashraf M, Shahid W, Shah SAA (2018)
Conventional versus microwave assisted synthesis, molecular docking and enzyme inhibitory activities of new 3,4,5-trisubstituted-1,2,4-triazole analogues
Pak J Pharm Sci 31: 1501
Ali M, Muhammad S, Shah MR, Khan A, Rashid U, Farooq U, Ullah F, Sadiq A, Ayaz M, Ahmad M, Latif A (2017)
Neurologically Potent Molecules from Crataegus oxyacantha; Isolation, Anticholinesterase Inhibition, and Molecular Docking
Front Pharmacol 8: 327
Sarfraz M, Sultana N, Rashid U, Akram MS, Sadiq A, Tariq MI (2017)
Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases
Bioorg Chem 70: 237
Sultana N, Sarfraz M, Tanoli ST, Akram MS, Sadiq A, Rashid U, Tariq MI (2017)
Synthesis, crystal structure determination, biological screening and docking studies of N1-substituted derivatives of 2,3-dihydroquinazolin-4(1H)-one as inhibitors of cholinesterases
Bioorg Chem 72: 256
Ansari FL, Iftikhar F, Ihsan Ul H, Mirza B, Baseer M, Rashid U (2008)
Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines
Bioorganic & Medicinal Chemistry 16: 7691