Espinosa-Jimenez T, Cano A, Sanchez-Lopez E, Olloquequi J, Folch J, Bullo M, Verdaguer E, Auladell C, Pont C, Munoz-Torrero D, Parcerisas A, Camins A, Ettcheto M (2023) <br />A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet<br /><i>Cell Biosci</i> <b>13</b>: 52<br /><br />Codony S, Pont C, Grinan-Ferre C, Di Pede-Mattatelli A, Calvo-Tusell C, Feixas F, Osuna S, Jarne-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Perez B, Bartra C, Sanfeliu C, Juarez-Jimenez J, Morisseau C, Hammock BD, Pallas M, Vazquez S, Munoz-Torrero D (2022) <br />Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease<br /><i>Journal of Medicinal Chemistry</i> <b>65</b>: 4909<br /><br />Pont C, Ginex T, Grinan-Ferre C, Scheiner M, Mattellone A, Martinez N, Arce EM, Soriano-Fernandez Y, Naldi M, De Simone A, Barenys M, Gomez-Catalan J, Perez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallas M, Luque FJ, Munoz-Torrero D (2021) <br />From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects<br /><i>Eur Journal of Medicinal Chemistry</i> <b>225</b>: 113779<br /><br />Perez-Areales FJ, Turcu AL, Barniol-Xicota M, Pont C, Pivetta D, Espargaro A, Bartolini M, De Simone A, Andrisano V, Perez B, Sabate R, Sureda FX, Vazquez S, Munoz-Torrero D (2019) <br />A novel class of multitarget anti-Alzheimer benzohomoadamantanechlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors<br /><i>Eur Journal of Medicinal Chemistry</i> <b>180</b>: 613<br /><br />Raymond O, Gouzy J, Just J, Badouin H, Verdenaud M, Lemainque A, Vergne P, Moja S, Choisne N, Pont C, Carrere S, Caissard JC, Couloux A, Cottret L, Aury JM, Szecsi J, Latrasse D, Madoui MA, Francois L, Fu X, Yang SH, Dubois A, Piola F, Larrieu A, Perez M, Labadie K, Perrier L, Govetto B, Labrousse Y, Villand P, Bardoux C, Boltz V, Lopez-Roques C, Heitzler P, Vernoux T, Vandenbussche M, Quesneville H, Boualem A, Bendahmane A, Liu C, Le Bris M, Salse J, Baudino S, Benhamed M, Wincker P, Bendahmane M (2018) <br />The Rosa genome provides new insights into the domestication of modern roses<br /><i>Nat Genet</i> <b>50</b>: 772<br /><br />Perez-Areales FJ, Betari N, Viayna A, Pont C, Espargaro A, Bartolini M, De Simone A, Rinaldi Alvarenga JF, Perez B, Sabate R, Lamuela-Raventos RM, Andrisano V, Luque FJ, Munoz-Torrero D (2017) <br />Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids<br /><i>Future Med Chem</i> <b>9</b>: 965<br /><br />