Kuznetsova DA, Gaynanova GA, Vasilieva EA, Pavlov RV, Zueva IV, Babaev VM, Kuznetsov DM, Voloshina AD, Petrov KA, Zakharova LY, Sinyashin OG (2022) <br />Oxime Therapy for Brain AChE Reactivation and Neuroprotection after Organophosphate Poisoning<br /><i>Pharmaceutics</i> <b>14</b>: <br /><br />Lenina OA, Petrov KA (2022) <br />Balanced modulation of neuromuscular synaptic transmission via M1 and M2 muscarinic receptors during inhibition of cholinesterases<br /><i>Sci Rep</i> <b>12</b>: 1688<br /><br />Saifina LF, Abdalla M, Gubaidullina LM, Zueva IV, Eltayb WA, El-Arabey AA, Kharlamova AD, Lenina OA, Semenov VE, Petrov KA (2022) <br />Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning<br /><i>Eur Journal of Medicinal Chemistry</i> <b>246</b>: 114949<br /><br />Semenov VE, Zueva IV, Lushchekina SV, Suleimanov EG, Gubaidullina LM, Shulaeva MM, Lenina OA, Petrov KA (2022) <br />Novel Uracil-Based Inhibitors of Acetylcholinesterase with Potency for Treating Memory Impairment in an Animal Model of Alzheimer's Disease<br /><i>Molecules</i> <b>27</b>: <br /><br />Vasilieva EA, Kuznetsova DA, Valeeva FG, Kuznetsov DM, Zakharov AV, Amerhanova SK, Voloshina AD, Zueva IV, Petrov KA, Zakharova LY (2022) <br />Therapy of Organophosphate Poisoning via Intranasal Administration of 2-PAM-Loaded Chitosomes<br /><i>Pharmaceutics</i> <b>14</b>: <br /><br />Petrov KA, Proskurina SE, Krejci E (2021) <br />Cholinesterases in Tripartite Neuromuscular Synapse<br /><i>Front Mol Neurosci</i> <b>14</b>: 811220<br /><br />Zueva IV, Lenina OA, Kayumova RM, Petrov KA, Masson P (2021) <br />Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments<br /><i>Chemico-Biological Interactions</i> <b>345</b>: 109558<br /><br />Burilova EA, Pashirova TN, Zueva IV, Gibadullina EM, Lushchekina SV, Sapunova AS, Kayumova RM, Rogov AM, Evtjugin VG, Sudakov IA, Vyshtakalyuk AB, Voloshina AD, Bukharov SV, Burilov AR, Petrov KA, Zakharova LY, Sinyashin OG (2020) <br />Bi-functional sterically hindered phenol lipid-based delivery systems as potential multi-target agents against Alzheimer's disease via an intranasal route<br /><i>Nanoscale</i> <b>12</b>: 13757<br /><br />Buzyurova DN, Pashirova TN, Zueva IV, Burilova EA, Shaihutdinova ZM, Rizvanov IK, Babaev VM, Petrov KA, Souto EB (2020) <br />Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: pharmacokinetics in rat<br /><i>Toxicology</i> <br /><br />Lenina OA, Zueva IV, Zobov VV, Semenov VE, Masson P, Petrov KA (2020) <br />Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning<br /><i>Sci Rep</i> <b>10</b>: 16611<br /><br />Pavlov RV, Gaynanova GA, Kuznetsova DA, Vasileva LA, Zueva IV, Sapunova AS, Buzyurova DN, Babaev VM, Voloshina AD, Lukashenko SS, Kh Rizvanov I, Petrov KA, Ya Zakharova L, Sinyashin OG (2020) <br />Biomedical potentialities of cationic geminis as modulating agents of liposome in drug delivery across biological barriers and cellular uptake<br /><i>Int J Pharm</i> <br /><br />Semenov VE, Zueva IV, Mukhamedyarov MA, Lushchekina SV, Petukhova EO, Gubaidullina LM, Krylova ES, Saifina LF, Lenina OA, Petrov KA (2020) <br />Novel Acetylcholinesterase Inhibitors Based on Uracil Moiety for Possible Treatment of Alzheimer Disease<br /><i>Molecules</i> <b>25</b>: <br /><br />Padnya PL, Bayarashov EE, Zueva IV, Lushchekina SV, Lenina OA, Evtugyn VG, Osin YN, Petrov KA, Stoikov, II (2019) <br />Water-soluble betaines and amines based on thiacalix[4]arene scaffold as new cholinesterase inhibitors<br /><i>Bioorg Chem</i> <br /><br />Pashirova TN, Burilova EA, Tagasheva RG, Zueva IV, Gibadullina EM, Nizameev IR, Sudakov IA, Vishtakalyk AB, Voloshina AD, Kadirov MK, Petrov KA, Burilov AR, Bukharov SV, Zakharova LY (2019) <br />Delivery nanosystems based on sterically hindered phenol derivatives containing a quaternary ammonium moiety: Synthesis, cholinesterase inhibition and antioxidant activity<br /><i>Chemico-Biological Interactions</i> <br /><br />Semenov VE, Zueva IV, Lushchekina SV, Lenina OA, Gubaidullina LM, Saifina LF, Shulaeva MM, Kayumova RM, Saifina AF, Gubaidullin AT, Kondrashova SA, Latypov SK, Masson P, Petrov KA (2019) <br />6-Methyluracil derivatives as peripheral site ligand-hydroxamic acid conjugates: Reactivation for paraoxon-inhibited acetylcholinesterase<br /><i>Eur Journal of Medicinal Chemistry</i> <b>185</b>: 111787<br /><br />Zueva IV, Dias J, Lushchekina SV, Semenov VE, Mukhamedyarov MA, Pashirova TN, Babaev VM, Nachon F, Petrova N, Nurullin LF, Zakharova LY, Ilyin VI, Masson P, Petrov KA (2019) <br />New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease<br /><i>Neuropharmacology</i> <b>155</b>: 131<br /><br />Mukhametshina A, Petrov A, Fedorenko S, Petrov KA, Nizameev I, Mustafina A, Sinyashin O (2018) <br />Luminescent nanoparticles for rapid monitoring of endogenous acetylcholine release in mice atria<br /><i>Luminescence</i> <b>33</b>: 588<br /><br />Mukhametshina AR, Fedorenko SV, Petrov AM, Zakyrjanova GF, Petrov KA, Nurullin LF, Nizameev IR, Mustafina AR, Sinyashin OG (2018) <br />Targeted Nanoparticles for Selective Marking of Neuromuscular Junctions and ex Vivo Monitoring of Endogenous Acetylcholine Hydrolysis<br /><i>ACS Appl Mater Interfaces</i> <b>10</b>: 14948<br /><br />Pashirova TN, Zueva IV, Petrov KA, Lukashenko SS, Nizameev IR, Kulik NV, Voloshina AD, Almasy L, Kadirov MK, Masson P, Souto EB, Zakharova LY, Sinyashin OG (2018) <br />Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model<br /><i>Colloids Surf B Biointerfaces</i> <b>171</b>: 358<br /><br />Pashirova TN, Braiki A, Zueva IV, Petrov KA, Babaev VM, Burilova EA, Samarkina DA, Rizvanov IK, Souto EB, Jean L, Renard PY, Masson P, Zakharova LY, Sinyashin OG (2018) <br />Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection<br /><i>J Control Release</i> <b>290</b>: 102<br /><br />Petrov KA, Kharlamova AD, Lenina OA, Nurtdinov AR, Sitdykova ME, Ilyin VI, Zueva IV, Nikolsky EE (2018) <br />Specific inhibition of acetylcholinesterase as an approach to decrease muscarinic side effects during myasthenia gravis treatment<br /><i>Sci Rep</i> <b>8</b>: 304<br /><br />Petrov KA, Zueva IV, Kovyazina IV, Sedov I, Lushchekina SV, Kharlamova AD, Lenina O, Koshkin S, Shtyrlin Y, Nikolsky EE, Masson P (2018) <br />C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies<br /><i>Neuropharmacology</i> <b>131</b>: 304<br /><br />Petrov KA, Nikolsky EE, Masson P (2018) <br />Autoregulation of Acetylcholine Release and Micro-Pharmacodynamic Mechanisms at Neuromuscular Junction: Selective Acetylcholinesterase Inhibitors for Therapy of Myasthenic Syndromes<br /><i>Front Pharmacol</i> <b>9</b>: 766<br /><br />Pashirova TN, Zueva IV, Petrov KA, Babaev VM, Lukashenko SS, Rizvanov IK, Souto EB, Nikolsky EE, Zakharova LY, Masson P, Sinyashin OG (2017) <br />Nanoparticle-Delivered 2-PAM for Rat Brain Protection against Paraoxon Central Toxicity<br /><i>ACS Appl Mater Interfaces</i> <b>9</b>: 16922<br /><br />Elistratova JG, Mustafina AR, Brylev KA, Petrov KA, Shestopalov MA, Mironov YV, Babaev VM, Rizvanov IK, Masson P, Sinyashin OG (2016) <br />Sensing activity of cholinesterases through a luminescence response of the hexarhenium cluster complex [{Re6S8}(OH)6](4.)<br /><i>Analyst</i> <b>141</b>: 4204<br /><br />Kharlamova AD, Lushchekina SV, Petrov KA, Kots ED, Nachon F, Villard-Wandhammer M, Zueva IV, Krejci E, Reznik VS, Zobov VV, Nikolsky EE, Masson P (2016) <br />Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment<br /><i>Biochemical Journal</i> <b>473</b>: 1225<br /><br />Strelnik AD, Petukhov AS, Zueva IV, Zobov VV, Petrov KA, Nikolsky EE, Balakin KV, Bachurin SO, Shtyrlin YG (2016) <br />Novel potent pyridoxine-based inhibitors of AChE and BChE, structural analogs of pyridostigmine, with improved in vivo safety profile<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>26</b>: 4092<br /><br />Lushchekina SV, Kots ED, Kharlamova AD, Petrov KA, Masson P (2015) <br />Molecular modeling of mechanism of action of anti-myasthenia gravis slow-binding inhibitor of acetylcholinesterase<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S74<br /><br />Mukhametshina AR, Fedorenko SV, Zueva IV, Petrov KA, Masson P, Nizameev IR, Mustafina AR, Sinyashin OG (2015) <br />Luminescent silica nanoparticles for sensing acetylcholinesterase-catalyzed hydrolysis of acetylcholine<br /><i>Biosensors & Bioelectronics</i> <b>77</b>: 871<br /><br />Petrov KA (2015) <br />Macrocyclic derivatives of 6-methyluracil: New ligands of the peripheral anionic site of acetylcholinesterase<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S72<br /><br />Semenov VE, Zueva IV, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS (2015) <br />6-Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease<br /><i>ChemMedChem</i> <b>10</b>: 1863<br /><br />Zueva IV, Semenov VE, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS (2015) <br />6-Methyluracil derivatives as acetylcholinesterase inhibitors for treatment of Alzheimer's disease<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S69<br /><br />Petrov KA, Girard E, Nikitashina AD, Colasante C, Bernard V, Nurullin LF, Leroy J, Samigullin D, Colak O, Nikolsky EE, Plaud B, Krejci E (2014) <br />Schwann Cells Sense and Control Acetylcholine Spillover at the Neuromuscular Junction by alpha7 Nicotinic Receptors and Butyrylcholinesterase<br /><i>Journal of Neuroscience</i> <b>34</b>: 11870<br /><br />Nikitashina AD, Petrov KA, Zobov VV, Reznik VS, Nikolsky EE (2013) <br />Specific inhibitory effects of the alkylammonium derivative 6-methyluracil on acetylcholinesterase of smooth and striated muscles in rats<br /><i>Dokl Biol Sci</i> <b>449</b>: 82<br /><br />Petrov KA, Malomouzh AI, Kovyazina IV, Krejci E, Nikitashina AD, Proskurina SE, Zobov VV, Nikolsky EE (2013) <br />Regulation of acetylcholinesterase activity by nitric oxide in rat neuromuscular junction via N-methyl-d-aspartate receptor activation<br /><i>European Journal of Neuroscience</i> <b>37</b>: 181<br /><br />Lindovsky J, Petrov KA, Krusek J, Reznik VS, Nikolsky EE, Vyskocil F (2012) <br />Effect of tissue-specific acetylcholinesterase inhibitor C-547 on alpha3beta4 and alphabetaepsilondelta acetylcholine receptors in COS cells<br /><i>European Journal of Pharmacology</i> <b>688</b>: 22<br /><br />Petrov KA, Yagodina LO, Valeeva GR, Lannik NI, Nikitashina AD, Rizvanov AA, Zobov VV, Bukharaeva EA, Reznik VS, Nikolsky EE, Vyskocil F (2011) <br />Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS)<br /><i>British Journal of Pharmacology</i> <b>163</b>: 732<br /><br />Abramochkin DV, Petrov KA, Zobov VV, Iagodina LO, Nikol'skii EE, Rozenshtraukh LV (2009) <br />[The study of effects of a novel acetylcholinesterase inhibitor on electrical activity of the heart]<br /><i>Kardiologiia</i> <b>49</b>: 47<br /><br />Abramochkin DV, Petrov KA, Zobov VV, Yagodina LO, Nikolsky EE, Rosenshtraukh LV (2009) <br />Mechanisms of cardiac muscle insensitivity to a novel acetylcholinesterase inhibitor C-547<br /><i>J Cardiovasc Pharmacol</i> <b>53</b>: 162<br /><br />Petrov KA, Kovyazina IV, Zobov VV, Bukharaeva EA, Nikolsky EE, Vyskocil F (2009) <br />Different sensitivity of miniature endplate currents in rat external and internal intercostal muscles to the acetylcholinesterase inhibitor C-547 as compared with diaphragm and extensor digitorum longus<br /><i>Physiol Res</i> <b>58</b>: 149<br /><br />Petrov KA, Kovyazina IV, Zobov VV, Bukharaeva EA, Reznik VS, Nikolsky EE (2007) <br />Effect of a tetraalkylammonium derivative of 6-methyluracil from a new class of acetylcholinesterase inhibitors on the endplate potential amplitude in muscles of different function types under high-frequency nerve stimulation<br /><i>Dokl Biol Sci</i> <b>415</b>: 261<br /><br />Petrov KA, Kovyazina LV, Zobov VV, Bukharaeva EA, Nikolsky EE, Vyskocil F (2006) <br />Different sensitivity of miniature endplate currents of the rat extensor digitorum longus, soleus and diaphragm muscles to a novel acetylcholinesterase inhibitor C-547<br /><i>Physiol Res</i> <b>55</b>: 585<br /><br />Zobov VV, Petrov KA, Asliamova AA, Beresinskii LA, Akamsin VD, Galiametdinova IV, Reznik VS (2005) <br />Selective blockade of locomotor muscles by uracil-containing tetraalkylammonium acetylcholinesterase inhibitors<br /><i>Dokl Biol Sci</i> <b>401</b>: 77<br /><br />