Uliassi E, Bergamini C, Rizzardi N, Naldi M, Cores A, Bartolini M, Carlos Menendez J, Bolognesi ML (2023) <br />Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease<br /><i>Bioorganic & Medicinal Chemistry</i> <b>91</b>: 117419<br /><br />Codony S, Pont C, Grinan-Ferre C, Di Pede-Mattatelli A, Calvo-Tusell C, Feixas F, Osuna S, Jarne-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Perez B, Bartra C, Sanfeliu C, Juarez-Jimenez J, Morisseau C, Hammock BD, Pallas M, Vazquez S, Munoz-Torrero D (2022) <br />Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease<br /><i>Journal of Medicinal Chemistry</i> <b>65</b>: 4909<br /><br />Montanari S, Allara M, Scalvini L, Kostrzewa M, Belluti F, Gobbi S, Naldi M, Rivara S, Bartolini M, Ligresti A, Bisi A, Rampa A (2021) <br />New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators<br /><i>Molecules</i> <b>26</b>: 3254<br /><br />Naldi M, Brusotti G, Massolini G, Andrisano V, Temporini C, Bartolini M (2021) <br />Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity<br /><i>Molecules</i> <b>26</b>: <br /><br />Pont C, Ginex T, Grinan-Ferre C, Scheiner M, Mattellone A, Martinez N, Arce EM, Soriano-Fernandez Y, Naldi M, De Simone A, Barenys M, Gomez-Catalan J, Perez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallas M, Luque FJ, Munoz-Torrero D (2021) <br />From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects<br /><i>Eur Journal of Medicinal Chemistry</i> <b>225</b>: 113779<br /><br />de Andrade Ramos G, Souza de Oliveira A, Bartolini M, Naldi M, Liparulo I, Bergamini C, Uliassi E, Wu L, Fraser PE, Abreu M, Kiametis AS, Gargano R, Silveira ER, Brand GD, Prchal L, Soukup O, Korabecny J, Bolognesi ML, Soares Romeiro LA (2021) <br />Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties<br /><i>RSC Med Chem</i> <b>12</b>: 1154<br /><br />Cieslikiewicz-Bouet M, Naldi M, Bartolini M, Perez B, Servent D, Jean L, Araoz R, Renard PY (2020) <br />Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor<br /><i>Biochemical Pharmacology</i> <br /><br />De Simone A, Naldi M, Tedesco D, Bartolini M, Davani L, Andrisano V (2019) <br />Advanced analytical methodologies in Alzheimer's disease drug discovery<br /><i>J Pharm Biomed Anal</i> <b>178</b>: 112899<br /><br />Montanari S, Mahmoud AM, Pruccoli L, Rabbito A, Naldi M, Petralla S, Moraleda I, Bartolini M, Monti B, Iriepa I, Belluti F, Gobbi S, Di Marzo V, Bisi A, Tarozzi A, Ligresti A, Rampa A (2019) <br />Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment<br /><i>Eur Journal of Medicinal Chemistry</i> <b>178</b>: 243<br /><br />Oukoloff K, Coquelle N, Bartolini M, Naldi M, Le Guevel R, Bach S, Josselin B, Ruchaud S, Catto M, Pisani L, Denora N, Iacobazzi RM, Silman I, Sussman JL, Buron F, Colletier JP, Jean L, Routier S, Renard PY (2019) <br />Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3<br /><i>Eur Journal of Medicinal Chemistry</i> <b>168</b>: 58<br /><br />Scheiner M, Dolles D, Gunesch S, Hoffmann M, Nabissi M, Marinelli O, Naldi M, Bartolini M, Petralla S, Poeta E, Monti B, Falkeis C, Vieth M, Hubner H, Gmeiner P, Maitra R, Maurice T, Decker M (2019) <br />Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo<br /><i>Journal of Medicinal Chemistry</i> <b>62</b>: 9078<br /><br />Andrisano V, Naldi M, De Simone A, Bartolini M (2018) <br />A patent review of butyrylcholinesterase inhibitors and reactivators 2010-2017<br /><i>Expert Opin Ther Pat</i> <b>28</b>: 455<br /><br />Rampa A, Bartolini M, Pruccoli L, Naldi M, Iriepa I, Moraleda I, Belluti F, Gobbi S, Tarozzi A, Bisi A (2018) <br />Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer's Disease<br /><i>Molecules</i> <b>23</b>: <br /><br />Bartolini M, Naldi M, Nicolau DV, van Delft FC, van Zijl J, Snijder J, van den Heuvel EF, Naburgh EP, Calonghi N, Andrisano V (2013) <br />Fluorescence biosensing micropatterned surfaces based on immobilized human acetylcholinesterase<br /><i>Anal Bioanal Chem</i> <b>405</b>: 795<br /><br />Mancini F, Naldi M, Cavrini V, Andrisano V (2007) <br />Multiwell fluorometric and colorimetric microassays for the evaluation of beta-secretase (BACE-1) inhibitors<br /><i>Anal Bioanal Chem</i> <b>388</b>: 1175<br /><br />