Molgo J, Marchot P, Araoz R, Benoit E, Iorga BI, Zakarian A, Taylor P, Bourne Y, Servent D (2017) <br />Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors<br /><i>Journal of Neurochemistry</i> <b>142 Suppl 2</b>: 41<br /><br />Benoit E, Barbier J, Popoff MR, Faure G, Molgo J, Servent D (2016) <br />Special Issue on Toxins: New targets and new functions<br /><i>Toxicon</i> <b>116</b>: 1<br /><br />Sigoillot SM, Bourgeois F, Karmouch J, Molgo J, Dobbertin A, Chevalier C, Houlgatte R, Leger J, Legay C (2016) <br />Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency<br /><i>FASEB Journal</i> <b>30</b>: 2382<br /><br />Araoz R, Bouet m, Bartolini M, Coquelle N, Colletier JP, Servent D, Molgo J, Jean L, Renard PY (2015) <br />Poster: Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of alpha7 nicotinic acetylcholine receptor<br /><i>Biochemical Pharmacology</i> <b>97</b>: 621<br /><br />Araoz R, Hess P, Pelissier F, Benoit E, Servent D, Zakarian A, Molgo J (2015) <br />Poster: Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives<br /><i>Biochemical Pharmacology</i> <b>97</b>: 622<br /><br />Bourne Y, Sulzenbacher G, Radic Z, Araoz R, Reynaud M, Benoit E, Zakarian A, Servent D, Molgo J, Taylor P, Marchot P (2015) <br />Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha7 from Muscle alpha1(2)betagammadelta nAChRs<br /><i>Structure</i> <b>23</b>: 1106<br /><br />Messeant J, Dobbertin A, Girard E, Delers P, Manuel M, Mangione F, Schmitt A, Le Denmat D, Molgo J, Zytnicki D, Schaeffer L, Legay C, Strochlic L (2015) <br />MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance<br /><i>Journal of Neuroscience</i> <b>35</b>: 4926<br /><br />Rubio F, Kamp L, Carpino J, Faltin E, Loftin K, Molgo J, Araoz R (2014) <br />Colorimetric microtiter plate receptor-binding assay for the detection of freshwater and marine neurotoxins targeting the nicotinic acetylcholine receptors<br /><i>Toxicon</i> <b>91</b>: 45<br /><br />Sanchez JA, Otero P, Alfonso A, Ramos V, Vasconcelos V, Araoz R, Molgo J, Vieytes MR, Botana LM (2014) <br />Detection of Anatoxin-a and Three Analogs in Anabaena spp. Cultures: New Fluorescence Polarization Assay and Toxin Profile by LC-MS/MS<br /><i>Toxins (Basel)</i> <b>6</b>: 402<br /><br />Hess P, Abadie E, Herve F, Berteaux T, Sechet V, Araoz R, Molgo J, Zakarian A, Sibat M, Rundberget T, Miles CO, Amzil Z (2013) <br />Pinnatoxin G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon<br /><i>Toxicon</i> <b>75</b>: 16<br /><br />Corbel V, Stankiewicz M, Pennetier C, Fournier D, Stojan J, Girard E, Dimitrov M, Molgo J, Hougard JM, Lapied B (2012) <br />Correction: Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet<br /><i>BMC Biol</i> <b>10</b>: 86<br /><br />Grandic M, Araoz R, Molgo J, Turk T, Sepcic K, Benoit E, Frangez R (2012) <br />The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors<br /><i>Toxicol Appl Pharmacol</i> <b>265</b>: 221<br /><br />Jackson JJ, Stivala CE, Iorga BI, Molgo J, Zakarian A (2012) <br />Stability of cyclic imine toxins: interconversion of pinnatoxin amino ketone and pinnatoxin A in aqueous media<br /><i>J Org Chem</i> <b>77</b>: 10435<br /><br />Araoz R, Servent D, Molgo J, Iorga BI, Fruchart-Gaillard C, Benoit E, Gu Z, Stivala C, Zakarian A (2011) <br />Total synthesis of pinnatoxins A and G and revision of the mode of action of pinnatoxin A<br /><i>Journal of the American Chemical Society</i> <b>133</b>: 10499<br /><br />Araoz R, Molgo J, Tandeau de Marsac N (2010) <br />Neurotoxic cyanobacterial toxins<br /><i>Toxicon</i> <b>56</b>: 813<br /><br />Bourne Y, Radic Z, Araoz R, Talley TT, Benoit E, Servent D, Taylor P, Molgo J, Marchot P (2010) <br />Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism<br /><i>Proc Natl Acad Sci U S A</i> <b>107</b>: 6076<br /><br />Quinton L, Girard E, Maiga A, Rekik M, Lluel P, Masuyer G, Larregola M, Marquer C, Ciolek J, Magnin T, Wagner R, Molgo J, Thai R, Fruchart-Gaillard C, Mourier G, Chamot-Rooke J, Menez A, Palea S, Servent D, Gilles N (2010) <br />Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor<br /><i>British Journal of Pharmacology</i> <b>159</b>: 316<br /><br />Rozman KB, Araoz R, Sepcic K, Molgo J, Suput D (2010) <br />Parazoanthoxanthin A blocks Torpedo nicotinic acetylcholine receptors<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 384<br /><br />Bidon C, Lachuer J, Molgo J, Wierinckx A, De La Porte S, Pignol B, Christen Y, Meloni R, Koenig HL, Biguet NF, Mallet J (2009) <br />The extract of Ginkgo biloba EGb 761 reactivates a juvenile profile in the skeletal muscle of sarcopenic rats by transcriptional reprogramming<br /><i>PLoS ONE</i> <b>4</b>: e7998<br /><br />Corbel V, Stankiewicz M, Pennetier C, Fournier D, Stojan J, Girard E, Dimitrov M, Molgo J, Hougard JM, Lapied B (2009) <br />Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet<br /><i>BMC Biol</i> <b>7</b>: 47<br /><br />Krieger F, Mourot A, Araoz R, Kotzyba-Hibert F, Molgo J, Bamberg E, Goeldner M (2008) <br />Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor<br /><i>Chembiochem</i> <b>9</b>: 1146<br /><br />Stum M, Girard E, Bangratz M, Bernard V, Herbin M, Vignaud A, Ferry A, Davoine CS, Echaniz-Laguna A, Rene F, Marcel C, Molgo J, Fontaine B, Krejci E, Nicole S (2008) <br />Evidence of a dosage effect and a physiological endplate acetylcholinesterase deficiency in the first mouse models mimicking Schwartz-Jampel syndrome neuromyotonia<br /><i>Hum Mol Genet</i> <b>17</b>: 3166<br /><br />Vignaud A, Fougerousse F, Mouisel E, Bertrand C, Bonafos B, Molgo J, Ferry A, Chatonnet A (2008) <br />Genetic ablation of acetylcholinesterase alters muscle function in mice<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 129<br /><br />Girard E, Bernard V, Minic J, Chatonnet A, Krejci E, Molgo J (2007) <br />Butyrylcholinesterase and the control of synaptic responses in acetylcholinesterase knockout mice<br /><i>Life Sciences</i> <b>80</b>: 2380<br /><br />Barbier J, Lamthanh H, Gall FL, Favreau P, Benoit E, Chen H, Gilles N, Ilan N, Heinemann SH, Gordon D, Menez A, Molgo J (2006) <br />d-Conopeptide EVIA isolated from Conus ermineus is a new pharmacological tool for discriminating sodium channel subtypes<br /><i>Journal de Physiologie (Paris)</i> <b>99</b>: 247<br /><br />Girard E, Barbier J, Camp S, Taylor P, Chatonnet A, Krejci E, Molgo J (2006) <br />Synaptic efficacy and remodeling at the neuromuscular junction of knockout mice deficient in acetylcholinesterase<br /><i>Journal de Physiologie (Paris)</i> <b>99</b>: 254<br /><br />Girard E, Bernard V, Camp S, Taylor P, Krejci E, Molgo J (2006) <br />Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase<br /><i>Journal of Molecular Neuroscience</i> <b>30</b>: 99<br /><br />Mouisel E, Blondet B, Escourrou P, Chatonnet A, Molgo J, Ferry A (2006) <br />Outcome of acetylcholinesterase deficiency for neuromuscular functioning<br /><i>Neurosci Res</i> <b>55</b>: 389<br /><br />Stum M, Girard E, Molgo J, Tabti N, Willer J-C, Fontaine B, Krejci E, Nicole S (2006) <br />Generation of a mouse model for Schwartz-Jampel syndrome<br /><i>Journal de Physiologie (Paris)</i> <b>99</b>: 275<br /><br />Girard E, Barbier J, Chatonnet A, Krejci E, Molgo J (2005) <br />Synaptic remodeling at the skeletal neuromuscular junction of acetylcholinesterase knockout mice and its physiological relevance<br /><i>Chemico-Biological Interactions</i> <b>157-158</b>: 87<br /><br />Montecucco C, Molgo J (2005) <br />Botulinal neurotoxins: revival of an old killer<br /><i>Curr Opin Pharmacol</i> <b>5</b>: 274<br /><br />Nguyen-Huu T, Dobbertin A, Barbier J, Minic J, Krejci E, Duvaldestin P, Molgo J (2005) <br />Cholinesterases and the resistance of the mouse diaphragm to the effect of tubocurarine<br /><i>Anesthesiology</i> <b>103</b>: 788<br /><br />Minic J, Barbier J, Chatonnet A, Krejci E, Molgo J (2004) <br />Synaptic transmission at AChE/- and CoIQ-I-knockout mouse neuromuscular junctions<br /><i>In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects</i> <b> (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina</b>: 19 <br /><br />Minic J, Barbier J, Chatonnet A, Krejci E, Molgo J (2004) <br />Poster (7) Synaptic transmission at AChE-/- and ColQ knockout mouse neuromuscular junctions<br /><i>In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects</i> <b> (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina</b>: 324<br /><br />Minic J, Chatonnet A, Krejci E, Molgo J (2003) <br />Butyrylcholinesterase and acetylcholinesterase activity and quantal transmitter release at normal and acetylcholinesterase knockout mouse neuromuscular junctions<br /><i>British Journal of Pharmacology</i> <b>138</b>: 177<br /><br />Minic J, Molgo J, Karlsson E, Krejci E (2002) <br />Regulation of acetylcholine release by muscarinic receptors at the mouse neuromuscular junction depends on the activity of acetylcholinesterase<br /><i>European Journal of Neuroscience</i> <b>15</b>: 439<br /><br />Poh SL, Mourier G, Thai R, Armugam A, Molgo J, Servent D, Jeyaseelan K, Menez A (2002) <br />A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken alpha7 nicotinic acetylcholine receptors<br /><i>European Journal of Biochemistry</i> <b>269</b>: 4247<br /><br />Feng G, Krejci E, Molgo J, Cunningham JM, Massoulie J, Sanes JR (1999) <br />Genetic Analysis of Collagen Q: Roles in Acetylcholinesterase and Butyrylcholinesterase Assembly and in Synaptic Structure and Function<br /><i>Journal of Cell Biology</i> <b>144</b>: 1349<br /><br />Cifuentes-Diaz C, Meunier FA, Velasco E, Faille L, Goudou D, Belkadi L, Rieger F, Molgo J, Angaut-Petit D (1998) <br />Morphological alterations of motor nerve terminals after botulinum type-A poisoning or reinnervation of skeletal muscle in the tenascin-C deficient mouse<br /><i>Journal de Physiologie (Paris)</i> <b>92</b>: 421<br /><br />Favreau P, Legall F, Servent D, Menez A, Molgo J, Letourneux Y (1998) <br />Two novel alpha-conotoxins isolated from the venom of Conus consor: isolation, synthesis and binding on the Torpedo nicotinic acetylcholine receptor<br /><i>Journal de Physiologie (Paris)</i> <b>92</b>: 430<br /><br />Le Gall F, Favreau P, Benoit E, Letourneux Y, Molgo J (1998) <br />61 Repetitive and spontaneous acetylcholine release from motor nerve terminals induced by a neurotoxin isolated from Conus ermineus venom<br /><i>Journal de Physiologie (Paris)</i> <b>92</b>: 456<br /><br />Juzans P, Comella JX, Molgo J, Faille L, Angaut-Petit D (1996) <br />Nerve terminal sprouting in botulinum type-A treated mouse levator auris longus muscle<br /><i>Neuromuscular Disorders</i> <b>6</b>: 177<br /><br />Molgo J, Guglielmi JM (1996) <br />3,4-Diaminopyridine, an orphan drug, in the symptomatic treatment of Lambert-Eaton myasthenic syndrome<br /><i>Pflugers Arch</i> <b>431</b>: R295<br /><br />Sellin LC, Molgo J, Tornquist K, Hansson B, Thesleff S (1996) <br />On the possible origin of giant or slow-rising miniature end-plate potentials at the neuromuscular junction<br /><i>Pflugers Arch</i> <b>431</b>: 325<br /><br />Varoqui H, Meunier FM, Meunier FA, Molgo J, Berrard S, Cervini R, Mallet J, Israel M, Diebler MF (1996) <br />Expression of the vesicular acetylcholine transporter in mammalian cells<br /><i>Prog Brain Res</i> <b>109</b>: 83<br /><br />Poulain B, Molgo J, Thesleff S (1995) <br />Quantal neurotransmitter release and the clostridial neurotoxins' targets<br /><i>Curr Top Microbiol Immunol</i> <b>195</b>: 243<br /><br />Van der Kloot W, Balezina OP, Molgo J, Naves LA (1994) <br />The timing of channel opening during miniature endplate currents at the frog and mouse neuromuscular junctions: effects of fasciculin-2, other anti-cholinesterases and vesamicol<br /><i>Pflugers Arch</i> <b>428</b>: 114<br /><br />Kreger AS, Molgo J, Comella JX, Hansson B, Thesleff S (1993) <br />Effects of stonefish (Synanceia trachynis) venom on murine and frog neuromuscular junctions<br /><i>Toxicon</i> <b>31</b>: 307<br /><br />Pecot-Dechavassine M, Molgo J, Thesleff S (1991) <br />Ultrastructure of botulinum type-A poisoned frog motor nerve terminals after enhanced quantal transmitter release caused by carbonyl cyanide m-chlorophenylhydrazone<br /><i>Neuroscience Letters</i> <b>130</b>: 5<br /><br />Molgo J, Comella JX, Angaut-Petit D, Pecot-Dechavassine M, Tabti N, Faille L, Mallart A, Thesleff S (1990) <br />Presynaptic actions of botulinal neurotoxins at vertebrate neuromuscular junctions<br /><i>Journal de Physiologie (Paris)</i> <b>84</b>: 152<br /><br />Thesleff S, Molgo J, Tagerud S (1990) <br />Trophic interrelations at the neuromuscular junction as revealed by the use of botulinal neurotoxins<br /><i>Journal de Physiologie (Paris)</i> <b>84</b>: 167<br /><br />Mallart A, Molgo J, Angaut-Petit D, Thesleff S (1989) <br />Is the internal calcium regulation altered in type A botulinum toxin-poisoned motor endings?<br /><i>Brain Research</i> <b>479</b>: 167<br /><br />Molgo J, DasGupta BR, Thesleff S (1989) <br />Characterization of the actions of botulinum neurotoxin type E at the rat neuromuscular junction<br /><i>Acta Physiologica Scandinavica</i> <b>137</b>: 497<br /><br />Molgo J, Pecot-Dechavassine M, Thesleff S (1989) <br />Effects of cadmium on quantal transmitter release and ultrastructure of frog motor nerve endings<br /><i>J Neural Transm</i> <b>77</b>: 79<br /><br />Molgo J, Siegel LS, Tabti N, Thesleff S (1989) <br />A study of synchronization of quantal transmitter release from mammalian motor endings by the use of botulinal toxins type A and D<br /><i>Journal of Physiology</i> <b>411</b>: 195<br /><br />Molgo J, Angaut-Petit D, Thesleff S (1987) <br />In botulinum type A-poisoned frog motor endings ouabain induces phasic transmitter release through Na+-Ca2+ exchange<br /><i>Brain Research</i> <b>410</b>: 385<br /><br />Molgo J, Lemeignan M, Thesleff S (1987) <br />Aminoglycosides and 3,4-diaminopyridine on neuromuscular block caused by botulinum type A toxin<br /><i>Muscle & Nerve</i> <b>10</b>: 464<br /><br />Lemeignan M, Millart H, Lamiable D, Molgo J, Lechat P (1984) <br />Evaluation of 4-aminopyridine and 3,4-diaminopyridine penetrability into cerebrospinal fluid in anesthetized rats<br /><i>Brain Research</i> <b>304</b>: 166<br /><br />Molgo J, Thesleff S (1984) <br />Studies on the mode of action of botulinum toxin type A at the frog neuromuscular junction<br /><i>Brain Research</i> <b>297</b>: 309<br /><br />Thesleff S, Molgo J (1983) <br />A new type of transmitter release at the neuromuscular junction<br /><i>Neuroscience</i> <b>9</b>: 1<br /><br />Thesleff S, Molgo J, Lundh H (1983) <br />Botulinum toxin and 4-aminoquinoline induce a similar abnormal type of spontaneous quantal transmitter release at the rat neuromuscular junction<br /><i>Brain Research</i> <b>264</b>: 89<br /><br />Colmeus C, Gomez S, Molgo J, Thesleff S (1982) <br />Discrepancies between spontaneous and evoked synaptic potentials at normal, regenerating and botulinum toxin poisoned mammalian neuromuscular junctions<br /><i>Proc R Soc Lond B Biol Sci</i> <b>215</b>: 63<br /><br />Molgo J, Gomez S, Polak RL, Thesleff S (1982) <br />Giant miniature endplate potentials induced by 4-aminoquinoline<br /><i>Acta Physiologica Scandinavica</i> <b>115</b>: 201<br /><br />Molgo J, Thesleff S (1982) <br />4-aminoquinoline-induced 'giant' miniature endplate potentials at mammalian neuromuscular junctions<br /><i>Proc R Soc Lond B Biol Sci</i> <b>214</b>: 229<br /><br />Molgo J, Thesleff S (1982) <br />Electronic properties of motor nerve terminals<br /><i>Acta Physiologica Scandinavica</i> <b>114</b>: 271<br /><br />Molgo J, Lundh H, Thesleff S (1980) <br />Potency of 3,4-diaminopyridine and 4-aminopyridine on mammalian neuromuscular transmission and the effect of pH changes<br /><i>European Journal of Pharmacology</i> <b>61</b>: 25<br /><br />