DeBay DR, Reid GA, Pottie IR, Martin E, Bowen CV, Darvesh S (2017)
Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease
Alzheimers Dement (N Y) 3: 166

DeBay DR, Reid GA, Macdonald IR, Mawko G, Burrell S, Martin E, Bowen CV, Darvesh S (2017)
Butyrylcholinesterase-knockout reduces fibrillar beta-amyloid and conserves (18)FDG retention in 5XFAD mouse model of Alzheimer's disease
Brain Research 1671: 102

Jollymore-Hughes CT, Pottie IR, Martin E, Rosenberry TL, Darvesh S (2016)
Development of acetophenone ligands as potential neuroimaging agents for cholinesterases
Bioorganic & Medicinal Chemistry 24: 5270

Macdonald IR, Reid GA, Pottie IR, Martin E, Darvesh S (2016)
Synthesis and Preliminary Evaluation of Phenyl 4-123I-Iodophenylcarbamate for Visualization of Cholinesterases Associated with Alzheimer Disease Pathology
J Nucl Med 57: 297

Macdonald IR, Rockwood K, Martin E, Darvesh S (2014)
Cholinesterase inhibition in Alzheimer's disease: is specificity the answer?
J Alzheimers Dis 42: 379

Darvesh S, Macdonald IR, Martin E (2013)
Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems
Bioorganic & Medicinal Chemistry Lett 23: 3822

Macdonald IR, Jollymore CT, Reid GA, Pottie IR, Martin E, Darvesh S (2013)
Thioesters for the in vitro evaluation of agents to image brain cholinesterases
J Enzyme Inhib Med Chem 28: 447

Darvesh S, Cash MK, Reid GA, Martin E, Mitnitski A, Geula C (2012)
Butyrylcholinesterase is associated with beta-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease
J Neuropathol Experimental Neurology 71: 2

Macdonald IR, Martin E, Rosenberry TL, Darvesh S (2012)
Probing the peripheral site of human butyrylcholinesterase
Biochemistry 51: 7046

Macdonald IR, Reid GA, Joy EE, Pottie IR, Matte G, Burrell S, Mawko G, Martin E, Darvesh S (2011)
Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase
Mol Imaging Biol 13: 1250

Rockwood K, Walsh R, Martin E, Darvesh S (2011)
Potentially procholinergic effects of medications commonly used in older adults
Am J Geriatr Pharmacother 9: 80

Walsh R, Rockwood K, Martin E, Darvesh S (2011)
Synergistic inhibition of butyrylcholinesterase by galantamine and citalopram
Biochimica & Biophysica Acta 1810: 1230

Darvesh S, Pottie IR, Darvesh KV, McDonald RS, Walsh R, Conrad S, Penwell A, Mataija D, Martin E (2010)
Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants
Bioorganic & Medicinal Chemistry 18: 2232

Darvesh S, Reid GA, Martin E (2010)
Biochemical and histochemical comparison of cholinesterases in normal and Alzheimer brain tissues
Curr Alzheimer Res 7: 386

Peter C, Schmidt K, Hofer S, Stephan M, Martin E, Weigand MA, Walther A (2010)
Effects of physostigmine on microcirculatory alterations during experimental endotoxemia
Shock 33: 405

Darvesh S, Darvesh KV, McDonald RS, Mataija D, Walsh R, Mothana S, Lockridge O, Martin E (2008)
Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase
Journal of Medicinal Chemistry 51: 4200

Hofer S, Eisenbach C, Lukic IK, Schneider L, Bode K, Brueckmann M, Mautner S, Wente MN, Encke J, Werner J, Dalpke AH, Stremmel W, Nawroth PP, Martin E, Krammer PH, Bierhaus A, Weigand MA (2008)
Pharmacologic cholinesterase inhibition improves survival in experimental sepsis
Critical Care Medicine 36: 404

Darvesh S, Walsh R, Martin E (2007)
Homocysteine thiolactone and human cholinesterases
Cellular Molecular Neurobiology 27: 33

Darvesh S, McDonald RS, Darvesh KV, Mataija D, Conrad S, Gomez G, Walsh R, Martin E (2007)
Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine
Bioorganic & Medicinal Chemistry 15: 6367

Walsh R, Martin E, Darvesh S (2007)
A versatile equation to describe reversible enzyme inhibition and activation kinetics: modeling beta-galactosidase and butyrylcholinesterase
Biochimica & Biophysica Acta 1770: 733

Darvesh S, McDonald RS, Darvesh KV, Mataija D, Mothana S, Cook H, Carneiro KM, Richard N, Walsh R, Martin E (2006)
On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases
Bioorganic & Medicinal Chemistry 14: 4586

Darvesh S, McDonald RS, Penwell A, Conrad S, Darvesh KV, Mataija D, Gomez G, Caines A, Walsh R, Martin E (2005)
Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives
Bioorganic & Medicinal Chemistry 13: 211

Darvesh S, Martin E, Walsh R, Rockwood K (2004)
Differential effects of lipid-lowering agents on human cholinesterases
Clinical Biochemistry 37: 42

Darvesh S, Arora RC, Martin E, Magee D, Hopkins DA, Armour JA (2004)
Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons
Experimental Neurology 188: 461

Darvesh S, Walsh R, Kumar R, Caines A, Roberts S, Magee D, Rockwood K, Martin E (2003)
Inhibition of human cholinesterases by drugs used to treat Alzheimer disease
Alzheimer Disease & Associated Disorders 17: 117

Darvesh S, Walsh R, Martin E (2003)
Enantiomer effects of huperzine A on the aryl acylamidase activity of human cholinesterases
Cellular Molecular Neurobiology 23: 93

Grisoni K, Gieseler K, Mariol MC, Martin E, Carre-Pierrat M, Moulder G, Barstead R, Segalat L (2003)
The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin
Journal of Molecular Biology 332: 1037

Darvesh S, Kumar R, Roberts S, Walsh R, Martin E (2001)
Butyrylcholinesterase-Mediated enhancement of the enzymatic activity of trypsin
Cellular Molecular Neurobiology 21: 285

Darvesh S, MacDonald SE, Losier AM, Martin E, Hopkins DA, Armour JA (1998)
Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activity
J Auton Nerv Syst 71: 75

Motsch J, Leuwer M, Bottiger BW, Bach A, Schonstedt R, Martin E (1995)
Dose-response, time-course of action and recovery of rocuronium bromide in children during halothane anaesthesia
European Journal of Anaesthesiology Supplement 11: 73