DeBay DR, Reid GA, Pottie IR, Martin E, Bowen CV, Darvesh S (2017) <br />Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease<br /><i>Alzheimers Dement (N Y)</i> <b>3</b>: 166<br /><br />DeBay DR, Reid GA, Macdonald IR, Mawko G, Burrell S, Martin E, Bowen CV, Darvesh S (2017) <br />Butyrylcholinesterase-knockout reduces fibrillar beta-amyloid and conserves (18)FDG retention in 5XFAD mouse model of Alzheimer's disease<br /><i>Brain Research</i> <b>1671</b>: 102<br /><br />Jollymore-Hughes CT, Pottie IR, Martin E, Rosenberry TL, Darvesh S (2016) <br />Development of acetophenone ligands as potential neuroimaging agents for cholinesterases<br /><i>Bioorganic & Medicinal Chemistry</i> <b>24</b>: 5270<br /><br />Macdonald IR, Reid GA, Pottie IR, Martin E, Darvesh S (2016) <br />Synthesis and Preliminary Evaluation of Phenyl 4-123I-Iodophenylcarbamate for Visualization of Cholinesterases Associated with Alzheimer Disease Pathology<br /><i>J Nucl Med</i> <b>57</b>: 297<br /><br />Macdonald IR, Rockwood K, Martin E, Darvesh S (2014) <br />Cholinesterase inhibition in Alzheimer's disease: is specificity the answer?<br /><i>J Alzheimers Dis</i> <b>42</b>: 379<br /><br />Darvesh S, Macdonald IR, Martin E (2013) <br />Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>23</b>: 3822<br /><br />Macdonald IR, Jollymore CT, Reid GA, Pottie IR, Martin E, Darvesh S (2013) <br />Thioesters for the in vitro evaluation of agents to image brain cholinesterases<br /><i>J Enzyme Inhib Med Chem</i> <b>28</b>: 447<br /><br />Darvesh S, Cash MK, Reid GA, Martin E, Mitnitski A, Geula C (2012) <br />Butyrylcholinesterase is associated with beta-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease<br /><i>J Neuropathol Experimental Neurology</i> <b>71</b>: 2<br /><br />Macdonald IR, Martin E, Rosenberry TL, Darvesh S (2012) <br />Probing the peripheral site of human butyrylcholinesterase<br /><i>Biochemistry</i> <b>51</b>: 7046<br /><br />Macdonald IR, Reid GA, Joy EE, Pottie IR, Matte G, Burrell S, Mawko G, Martin E, Darvesh S (2011) <br />Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase<br /><i>Mol Imaging Biol</i> <b>13</b>: 1250<br /><br />Rockwood K, Walsh R, Martin E, Darvesh S (2011) <br />Potentially procholinergic effects of medications commonly used in older adults<br /><i>Am J Geriatr Pharmacother</i> <b>9</b>: 80<br /><br />Walsh R, Rockwood K, Martin E, Darvesh S (2011) <br />Synergistic inhibition of butyrylcholinesterase by galantamine and citalopram<br /><i>Biochimica & Biophysica Acta</i> <b>1810</b>: 1230<br /><br />Darvesh S, Pottie IR, Darvesh KV, McDonald RS, Walsh R, Conrad S, Penwell A, Mataija D, Martin E (2010) <br />Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants<br /><i>Bioorganic & Medicinal Chemistry</i> <b>18</b>: 2232<br /><br />Darvesh S, Reid GA, Martin E (2010) <br />Biochemical and histochemical comparison of cholinesterases in normal and Alzheimer brain tissues<br /><i>Curr Alzheimer Res</i> <b>7</b>: 386<br /><br />Peter C, Schmidt K, Hofer S, Stephan M, Martin E, Weigand MA, Walther A (2010) <br />Effects of physostigmine on microcirculatory alterations during experimental endotoxemia<br /><i>Shock</i> <b>33</b>: 405<br /><br />Darvesh S, Darvesh KV, McDonald RS, Mataija D, Walsh R, Mothana S, Lockridge O, Martin E (2008) <br />Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase<br /><i>Journal of Medicinal Chemistry</i> <b>51</b>: 4200<br /><br />Hofer S, Eisenbach C, Lukic IK, Schneider L, Bode K, Brueckmann M, Mautner S, Wente MN, Encke J, Werner J, Dalpke AH, Stremmel W, Nawroth PP, Martin E, Krammer PH, Bierhaus A, Weigand MA (2008) <br />Pharmacologic cholinesterase inhibition improves survival in experimental sepsis<br /><i>Critical Care Medicine</i> <b>36</b>: 404<br /><br />Darvesh S, Walsh R, Martin E (2007) <br />Homocysteine thiolactone and human cholinesterases<br /><i>Cellular Molecular Neurobiology</i> <b>27</b>: 33<br /><br />Darvesh S, McDonald RS, Darvesh KV, Mataija D, Conrad S, Gomez G, Walsh R, Martin E (2007) <br />Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine<br /><i>Bioorganic & Medicinal Chemistry</i> <b>15</b>: 6367<br /><br />Walsh R, Martin E, Darvesh S (2007) <br />A versatile equation to describe reversible enzyme inhibition and activation kinetics: modeling beta-galactosidase and butyrylcholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>1770</b>: 733<br /><br />Darvesh S, McDonald RS, Darvesh KV, Mataija D, Mothana S, Cook H, Carneiro KM, Richard N, Walsh R, Martin E (2006) <br />On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases<br /><i>Bioorganic & Medicinal Chemistry</i> <b>14</b>: 4586<br /><br />Darvesh S, McDonald RS, Penwell A, Conrad S, Darvesh KV, Mataija D, Gomez G, Caines A, Walsh R, Martin E (2005) <br />Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives<br /><i>Bioorganic & Medicinal Chemistry</i> <b>13</b>: 211<br /><br />Darvesh S, Martin E, Walsh R, Rockwood K (2004) <br />Differential effects of lipid-lowering agents on human cholinesterases<br /><i>Clinical Biochemistry</i> <b>37</b>: 42<br /><br />Darvesh S, Arora RC, Martin E, Magee D, Hopkins DA, Armour JA (2004) <br />Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons<br /><i>Experimental Neurology</i> <b>188</b>: 461<br /><br />Darvesh S, Walsh R, Kumar R, Caines A, Roberts S, Magee D, Rockwood K, Martin E (2003) <br />Inhibition of human cholinesterases by drugs used to treat Alzheimer disease<br /><i>Alzheimer Disease & Associated Disorders</i> <b>17</b>: 117<br /><br />Darvesh S, Walsh R, Martin E (2003) <br />Enantiomer effects of huperzine A on the aryl acylamidase activity of human cholinesterases<br /><i>Cellular Molecular Neurobiology</i> <b>23</b>: 93<br /><br />Grisoni K, Gieseler K, Mariol MC, Martin E, Carre-Pierrat M, Moulder G, Barstead R, Segalat L (2003) <br />The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin<br /><i>Journal of Molecular Biology</i> <b>332</b>: 1037<br /><br />Darvesh S, Kumar R, Roberts S, Walsh R, Martin E (2001) <br />Butyrylcholinesterase-Mediated enhancement of the enzymatic activity of trypsin<br /><i>Cellular Molecular Neurobiology</i> <b>21</b>: 285<br /><br />Darvesh S, MacDonald SE, Losier AM, Martin E, Hopkins DA, Armour JA (1998) <br />Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activity<br /><i>J Auton Nerv Syst</i> <b>71</b>: 75<br /><br />Motsch J, Leuwer M, Bottiger BW, Bach A, Schonstedt R, Martin E (1995) <br />Dose-response, time-course of action and recovery of rocuronium bromide in children during halothane anaesthesia<br /><i>European Journal of Anaesthesiology Supplement</i> <b>11</b>: 73<br /><br />