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Potent dual MAGL/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain
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In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)m ethanone (JJKK-048)
Journal of Pharmacology & Experimental Therapeutics 359: 62
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Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase
Eur J Pharm Sci 77: 180
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Brain regional cannabinoid CB1 receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice
Eur J Pharm Sci 51: 87
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Discovery of Triterpenoids as Reversible Inhibitors of alpha/beta-hydrolase Domain Containing 12 (ABHD12)
PLoS ONE 9: e98286
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Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)
Molecular Pharmacology 86: 522
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Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase
Chemical Biology 20: 379
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Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats
Neuropharmacology 61: 891