Targowska-Duda KM, Maj M, Drczkowski P, Budzynska B, Boguszewska-Czubara A, Wrobel TM, Laitinen T, Kaczmar P, Poso A, Kaczor AA (2022) <br />WaterMap guided structure-based virtual screening for acetylcholinesterase inhibitors<br /><i>ChemMedChem</i> <br /><br />Navia-Paldanius D, Patel JZ, Lopez Navarro M, Jakupovic H, Goffart S, Pasonen-Seppanen S, Nevalainen TJ, Jaaskelainen T, Laitinen T, Laitinen JT, Savinainen JR (2016) <br />Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11)<br /><i>Eur J Pharm Sci</i> <b>93</b>: 253<br /><br />Kaczor AA, Targowska-Duda KM, Patel JZ, Laitinen T, Parkkari T, Adams Y, Nevalainen TJ, Poso A (2015) <br />Comparative molecular field analysis and molecular dynamics studies of alpha/beta hydrolase domain containing 6 (ABHD6) inhibitors<br /><i>J Mol Model</i> <b>21</b>: 2789<br /><br />Patel JZ, Nevalainen TJ, Savinainen JR, Adams Y, Laitinen T, Runyon RS, Vaara M, Ahenkorah S, Kaczor AA, Navia-Paldanius D, Gynther M, Aaltonen N, Joharapurkar AA, Jain MR, Haka AS, Maxfield FR, Laitinen JT, Parkkari T (2015) <br />Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors<br /><i>ChemMedChem</i> <b>10</b>: 253<br /><br />Patel JZ, Ahenkorah S, Vaara M, Staszewski M, Adams Y, Laitinen T, Navia-Paldanius D, Parkkari T, Savinainen JR, Walczynski K, Laitinen JT, Nevalainen TJ (2015) <br />Loratadine analogues as MAGL inhibitors<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>25</b>: 1436<br /><br />Patel JZ, van Bruchem J, Laitinen T, Kaczor AA, Navia-Paldanius D, Parkkari T, Savinainen JR, Laitinen JT, Nevalainen TJ (2015) <br />Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors<br /><i>Bioorganic & Medicinal Chemistry</i> <b>23</b>: 6335<br /><br />Korhonen J, Kuusisto A, van Bruchem J, Patel JZ, Laitinen T, Navia-Paldanius D, Laitinen JT, Savinainen JR, Parkkari T, Nevalainen TJ (2014) <br />Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)<br /><i>Bioorganic & Medicinal Chemistry</i> <b>22</b>: 6694<br /><br />Laitinen T, Navia-Paldanius D, Rytilahti R, Marjamaa JJ, Karizkova J, Parkkari T, Pantsar T, Poso A, Laitinen JT, Savinainen JR (2014) <br />Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency<br /><i>Molecular Pharmacology</i> <b>85</b>: 510<br /><br />Parkkari T, Haavikko R, Laitinen T, Navia-Paldanius D, Rytilahti R, Vaara M, Lehtonen M, Alakurtti S, Yli-Kauhaluoma J, Nevalainen T, Savinainen JR, Laitinen JT (2014) <br />Discovery of Triterpenoids as Reversible Inhibitors of alpha/beta-hydrolase Domain Containing 12 (ABHD12)<br /><i>PLoS ONE</i> <b>9</b>: e98286<br /><br />Savinainen JR, Kansanen E, Pantsar T, Navia-Paldanius D, Parkkari T, Lehtonen M, Laitinen T, Nevalainen T, Poso A, Levonen AL, Laitinen JT (2014) <br />Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)<br /><i>Molecular Pharmacology</i> <b>86</b>: 522<br /><br />Savinainen JR, Patel JZ, Parkkari T, Navia-Paldanius D, Marjamaa JJ, Laitinen T, Nevalainen T, Laitinen JT (2014) <br />Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5/ABHD16A)<br /><i>PLoS ONE</i> <b>9</b>: e109869<br /><br />Aaltonen N, Savinainen JR, Ribas CR, Ronkko J, Kuusisto A, Korhonen J, Navia-Paldanius D, Hayrinen J, Takabe P, Kasnanen H, Pantsar T, Laitinen T, Lehtonen M, Pasonen-Seppanen S, Poso A, Nevalainen T, Laitinen JT (2013) <br />Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase<br /><i>Chemical Biology</i> <b>20</b>: 379<br /><br />