Abdullaha M, Banoo R, Nuthakki VK, Sharma M, Kaur S, Thakur S, Kumar A, Jadhav HR, Bharate SB (2023)
Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship
ACS Omega 8: 17591
Anand PK, Saini V, Kaur J, Kumar A (2023)
Cell wall and immune modulation by Rv1800 (PPE28) helps M. smegmatis to evade intracellular killing
Int J Biol Macromol
Bhanukiran K, Singh SK, Singh R, Kumar A, Hemalatha S (2023)
Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer's Disease
ACS Chem Neurosci
Fontana IC, Kumar A, Nordberg A (2023)
The role of astrocytic alpha7 nicotinic acetylcholine receptors in Alzheimer disease
Nat Rev Neurol
Goyal SP, Agarwal T, Mishra V, Kumar A, Saravanan C (2023)
Adsorption Characterization of Lactobacillus sp. for Di-(2-ethylhexyl) phthalate
Probiotics Antimicrob Proteins
Gupta T, Singh V, Hefnawy M, Alanazi MM, Alsuwayt B, Kabra A, Kumar A, Pasricha C, Singh R (2023)
Ameliorating the Role of Aripiprazole in Memory Deficits Induced by Intracerebroventricular Streptozotocin-Induced Dementia of Alzheimer's Type
ACS Omega 8: 25295
Gutti G, Leifeld J, Kakarla R, Bajad NG, Ganeshpurkar A, Kumar A, Krishnamurthy S, Klein-Schmidt C, Tapken D, Hollmann M, Singh SK (2023)
Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease
Eur Journal of Medicinal Chemistry 259: 115670
Kumar A, Verma V, Dubey VK, Srivastava A, Garg SK, Singh VP, Arora PK (2023)
Industrial applications of fungal lipases: a review
Front Microbiol 14: 1142536
Kumar P, Singh A, Kumar A, Kumar R, Pal R, Sachan AK, Dixit RK, Nath R (2023)
Effect of Curcumin and Coenzyme Q10 Alone and in Combination on Learning and Memory in an Animal Model of Alzheimer's Disease
Biomedicines 11:
Mani S, Kaur A, Jakhar K, Kumari G, Sonar S, Kumar A, Das S, Kumar S, Kumar V, Kundu R, Pandey AK, Singh UP, Majumdar T (2023)
Targeting DPP4-RBD interactions by sitagliptin and linagliptin delivers a potential host-directed therapy against pan-SARS-CoV-2 infections
Int J Biol Macromol 245: 125444
Nuthakki VK, Choudhary S, Reddy CN, Bhatt S, Jamwal A, Jotshi A, Raghuvanshi R, Sharma A, Thakur S, Jadhav HR, Bharate SS, Nandi U, Kumar A, Bharate SB (2023)
Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448
ACS Chem Neurosci
P AA, Kumar A, Jangid K, Kumar V, Jaitak V (2023)
Structure-based Virtual Screening and Molecular Dynamic Simulation Approach for the Identification of Terpenoids as Potential DPP-4 Inhibitors
Curr Comput Aided Drug Des
Puranik S, Shukla L, Kundu A, Kamil D, Paul S, Venkadasamy G, Salim R, Singh SK, Kumar D, Kumar A (2023)
Exploring Potent Fungal Isolates from Sanitary Landfill Soil for In Vitro Degradation of Dibutyl Phthalate
J Fungi (Basel) 9:
Thakur A, Sharma B, Parashar A, Sharma V, Kumar A, Mehta V (2023)
2D-QSAR, molecular docking and MD simulation based virtual screening of the herbal molecules against Alzheimer's disorder: an approach to predict CNS activity
J Biomol Struct Dyn
Vergil Andrews JF, Selvaraj DB, Kumar A, Roshan SA, Anusuyadevi M, Kandasamy M (2023)
A Mild Dose of Aspirin Promotes Hippocampal Neurogenesis and Working Memory in Experimental Ageing Mice
Brain Sci 13:
Arya S, Singh P, Kaur J, Kumar A (2022)
Environment dependent expression of mycobacterium hormone sensitive lipases: expression pattern under ex-vivo and individual in-vitro stress conditions in M. tuberculosis H37Ra
Mol Biol Rep
Delogu GL, Fais A, Pintus F, Goyal C, Matos MJ, Era B, Kumar A (2022)
Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold
Pharmaceuticals (Basel) 15:
Ganeshpurkar A, Singh R, Kumar D, Gore P, Shivhare S, Sardana D, Rayala S, Kumar A, Singh SK (2022)
Identification of sulfonamide based butyrylcholinesterase inhibitors through scaffold hopping approach
Int J Biol Macromol
Ganeshpurkar A, Singh R, Kumar D, Gutti G, Gore P, Sahu B, Kumar A, Singh SK (2022)
Identification of sulfonamide-based butyrylcholinesterase inhibitors using machine learning
Future Med Chem
Ganeshpurkar A, Singh R, Singh RB, Kumar D, Kumar A, Singh SK (2022)
Identification of potential AChE inhibitors through combined machine-learning and structure-based design approaches
Indian J Biochem Biophys 59: 619
Gupta M, Kumar A, Prasun C, Nair MS, Kini SG, Yadav D, Nain S (2022)
Design, synthesis, extra-precision docking, and molecular dynamics simulation studies of pyrrolidin-2-one derivatives as potential acetylcholinesterase inhibitors
J Biomol Struct Dyn
Gupta M, Kumar A, Ojha M, Khan SK, Nain S (2022)
A Recent Appraisal of Small-Organic Molecules as Anti-Alzheimer's Agents
Mini Rev Med Chem
Kumar A, Mahajan A, Kumari P, Singh J, Raik S, Saha L, Pal A, Medhi B, Rattan V, Bhattacharyya S (2022)
Dental pulp stem cell secretome ameliorates d-galactose induced accelerated aging in rat model
Cell Biochemistry & Function
Kumar A, Nehra B, Singh D, Kuma D, Chawla PA (2022)
Recent advances in the development of nitrogen-containing heterocyclic Anti-Alzheimer's agents
Curr Top Med Chem
Parama D, Girisa S, Khatoon E, Kumar A, Alqahtani MS, Abbas M, Sethi G, Kunnumakkara AB (2022)
An overview of the pharmacological activities of scopoletin against different chronic diseases
Pharmacol Res 179: 106202
Raj A, Kumar A (2022)
Recent advances in assessment methods and mechanism of microbe-mediated chlorpyrifos remediation
Environ Research
Arora S, Kumar A (2021)
Mixture toxicity assessment of selected insecticides to silver perch fingerling, Bidyanus bidyanus
Ecotoxicology & Environmental Safety 226: 112790
Bajad NG, Swetha R, Gutti G, Singh M, Kumar A, Singh SK (2021)
A systematic review of carbohydrate-based bioactive molecules for Alzheimer's disease
Future Med Chem
Dutta A, Mandal A, Kundu A, Malik M, Chaudhary A, Khan MR, Shanmugam V, Rao U, Saha S, Patanjali N, Kumar R, Kumar A, Dash S, Singh PK, Singh A (2021)
Deciphering the Behavioral Response of Meloidogyne incognita and Fusarium oxysporum Toward Mustard Essential Oil
Front Plant Sci 12: 714730
Fatiha Muhammad E, Kumar A, Wahab HA, Zhang KYJ (2021)
Identification of 1,2,4-triazolylthioethanone Scaffold for the Design of New Acetylcholinesterase Inhibitors
Mol Inform
Floris S, Fais A, Medda R, Pintus F, Piras A, Kumar A, Kus PM, Westermark GT, Era B (2021)
Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
J Enzyme Inhib Med Chem 36: 517
Ganeshpurkar A, Singh R, Shivhare S, Divya, Kumar D, Gutti G, Kumar A, Singh SK (2021)
Improved machine learning scoring functions for identification of Electrophorus electricus's acetylcholinesterase inhibitors
Mol Divers
Ganeshpurkar A, Singh R, Kumar D, Gutti G, Sardana D, Shivhare S, Singh RB, Kumar A, Singh SK (2021)
Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus's butyrylcholinesterase inhibitors
J Biomol Struct Dyn
Kaur Gulati H, Choudhary S, Kumar N, Ahmed A, Bhagat K, Vir Singh J, Singh A, Kumar A, Singh Bedi PM, Singh H, Mukherjee D (2021)
Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity
Bioorg Chem 118: 105479
Khushboo, Kumar A, Sharma B (2021)
Biomedical Implications of Plant-Based Principles as Antidepressants: Prospects for Novel Drug Development
Mini Rev Med Chem
Kumar A, Chauhan S (2021)
Pancreatic lipase inhibitors: The road voyaged and successes
Life Sciences
Kumar M, Kumar A, Sindhu RK, Kushwah AS (2021)
Arbutin attenuates monosodium L-glutamate induced neurotoxicity and cognitive dysfunction in rats
Neurochem Int 151: 105217
Kumari B, Kaur J, Maan P, Kumar A (2021)
The lipolytic activity of LipJ, a stress-induced enzyme, is regulated by its C-terminal adenylate cyclase domain
Future Microbiol
Mathimaran A, Kumar A, Prajapati G, Ampapathi RS, Bora HK, Guha R (2021)
Partially saturated canthaxanthin alleviates aging-associated oxidative stress in D-galactose administered male wistar rats
Biogerontology 22: 19
Rani R, Kumar A, Jaggi AS, Singh N (2021)
Pharmacological investigations on efficacy of Phlorizin a sodium-glucose co-transporter (SGLT) inhibitor in mouse model of intracerebroventricular streptozotocin induced dementia of AD type
J Basic Clin Physiol Pharmacol
Virk D, Kumar A, Jaggi AS, Singh N (2021)
Ameliorative role of rolipram, PDE-4 inhibitor, against sodium arsenite-induced vascular dementia in rats
Environ Sci Pollut Res Int
Akhoon BA, Choudhary S, Tiwari H, Kumar A, Barik MR, Rathor L, Pandey R, Nargotra A (2020)
Discovery of a New Donepezil-like Acetylcholinesterase Inhibitor for Targeting Alzheimer's Disease: Computational Studies with Biological Validation
J Chem Inf Model 60: 4717
Bagri K, Kumar A, Manisha, Kumar P (2020)
Computational Studies on Acetylcholinesterase Inhibitors: From Biochemistry to Chemistry
Mini Rev Med Chem 20: 1403
Ben Ali W, Navarro D, Kumar A, Drula E, Turbe-Doan A, Correia LO, Baumberger S, Bertrand E, Faulds CB, Henrissat B, Sciara G, Mechichi T, Record E (2020)
Characterization of the CAZy Repertoire from the Marine-Derived Fungus Stemphylium lucomagnoense in Relation to Saline Conditions
Mar Drugs 18:
Dungdung A, Kumar A, Kumar B, Preetam M, Tara RK, Saba MK (2020)
Correlation and prognostic significance of serum amylase, serum lipase, and plasma cholinesterase in acute organophosphorus poisoning
J Family Med Prim Care 9: 1873
Kaur R, Kumar R, Verma S, Kumar A, Rajesh C, Sharma PK (2020)
Structural and functional insights about unique extremophilic bacterial lipolytic enzyme from metagenome source
Int J Biol Macromol
Kumar A, Anand PK, Chandel S, Shrivatava A, Kaur J (2020)
Molecular dynamics assisted mechanistic insight of Val430-Ala mutation of Rv1592c protein in isoniazid resistant Mycobacterium tuberculosis
Curr Comput Aided Drug Des
Kumar A, Mukhia S, Kumar N, Acharya V, Kumar S, Kumar R (2020)
A Broad Temperature Active Lipase Purified From a Psychrotrophic Bacterium of Sikkim Himalaya With Potential Application in Detergent Formulation
Front Bioeng Biotechnol 8: 642
Kumar A (2020)
Aspergillus nidulans: A Potential Resource of the Production of the Native and Heterologous Enzymes for Industrial Applications
Int J Microbiol 2020: 8894215
Kumar N, Kumar A, Sahoo SC, Chimni SS (2020)
Candida antarctica lipase-B-catalyzed kinetic resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles
Chirality 32: 1377
Balkrishna A, Pokhrel S, Tomer M, Verma S, Kumar A, Nain P, Gupta A, Varshney A (2019)
Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study
Molecules 24:
Ganeshpurkar A, Swetha R, Kumar D, Gangaram GP, Singh R, Gutti G, Jana S, Kumar A, Singh SK (2019)
Protein-Protein Interactions and Aggregation Inhibitors in Alzheimer's Disease
Curr Top Med Chem 19: 501
Gutti G, Kumar D, Paliwal P, Ganeshpurkar A, Lahre K, Kumar A, Krishnamurthy S, Singh SK (2019)
Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer's disease
Bioorg Chem 90: 103080
Gutti G, Kakarla R, Kumar D, Beohar M, Ganeshpurkar A, Kumar A, Krishnamurthy S, Singh SK (2019)
Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease
Eur Journal of Medicinal Chemistry 182: 111613
Kumar A, Mehta V, Raj U, Varadwaj PK, Udayabanu M, Yennamalli RM, Singh TR (2019)
Computational and In-Vitro Validation of Natural Molecules as Potential Acetylcholinesterase Inhibitors and Neuroprotective Agents
Curr Alzheimer Res 16: 116
Mishra P, Kumar A, Panda G (2019)
Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018)
Bioorganic & Medicinal Chemistry 27: 895
Nuthakki VK, Mudududdla R, Sharma A, Kumar A, Bharate SB (2019)
Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors
Bioorg Chem 90: 103062
Nuthakki VK, Sharma A, Kumar A, Bharate SB (2019)
Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent
Drug Dev Res 80: 655
Sinclair LI, Kumar A, Darreh-Shori T, Love S (2019)
Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas
Alzheimers Res Ther 11: 80
Yadav M, Jindal DK, Parle M, Kumar A, Dhingra S (2019)
Targeting oxidative stress, acetylcholinesterase, proinflammatory cytokine, dopamine and GABA by eucalyptus oil (Eucalyptus globulus) to alleviate ketamine-induced psychosis in rats
Inflammopharmacology 27: 301
Yadav P, Goyal VD, Gaur NK, Kumar A, Gokhale SM, Jamdar SN, Makde RD (2019)
Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms
Journal of Biological Chemistry 294: 89
Dhull DK, Kumar A (2018)
Tramadol ameliorates behavioural, biochemical, mitochondrial and histological alterations in ICV-STZ-induced sporadic dementia of Alzheimer's type in rats
Inflammopharmacology 26: 925
Fais A, Kumar A, Medda R, Pintus F, Delogu F, Matos MJ, Era B, Delogu GL (2018)
Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives
Bioorg Chem 84: 302
Kumar A, Pintus F, Di Petrillo A, Medda R, Caria P, Matos MJ, Vina D, Pieroni E, Delogu F, Era B, Delogu GL, Fais A (2018)
Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer's disease
Sci Rep 8: 4424
Kumar A, Chauhan S (2018)
Use of Simplified Molecular Input Line Entry System and molecular graph based descriptors in prediction and design of pancreatic lipase inhibitors
Future Med Chem 10: 1603
Kumar A, Lana E, Kumar R, Lithner CU, Darreh-Shori T (2018)
Soluble Abeta42 Acts as Allosteric Activator of the Core Cholinergic Enzyme Choline Acetyltransferase
Front Mol Neurosci 11: 327
Maan P, Kumar A, Kaur J (2018)
Rv1288, a Two Domain, Cell Wall Anchored, Nutrient Stress Inducible Carboxyl-Esterase of Mycobacterium tuberculosis, Modulates Cell Wall Lipid
Front Cell Infect Microbiol 8: 421
Mourya A, Akhtar A, Ahuja S, Sah SP, Kumar A (2018)
Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations
European Journal of Pharmacology 835: 31
Rijal S, Changdar N, Kinra M, Kumar A, Nampoothiri M, Arora D, Shenoy RR, Pai KSR, Joseph A, Mudgal J (2018)
Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats
Toxicol Mech Methods
Arora S, Balotra S, Pandey G, Kumar A (2017)
Binary combinations of organophosphorus and synthetic pyrethroids are more potent acetylcholinesterase inhibitors than organophosphorus and carbamate mixtures: An in vitro assessment
Toxicol Lett 268: 8
Kumar A, Singh N (2017)
Calcineurin inhibitors improve memory loss and neuropathological changes in mouse model of dementia
Pharmacol Biochem Behav 153: 147
Kumar A, Singh N (2017)
Inhibitor of Phosphodiestearse-4 improves memory deficits, oxidative stress, neuroinflammation and neuropathological alterations in mouse models of dementia of Alzheimer's Type
Biomed Pharmacother 88: 698
Kumar A, Singh N (2017)
Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer's type
Behav Pharmacol 28: 187
Kumar A, Singh SM, Singh R, Kaur J (2017)
Rv0774c, an iron stress inducible, extracellular esterase is involved in immune-suppression associated with altered cytokine and TLR2 expression
Int J Med Microbiol 307: 126
Kumar A, Manisha, Sangha GK, Shrivastava A, Kaur J (2017)
The immunosuppressive effects of a novel recombinant LipQ (Rv2485c) protein of Mycobacterium tuberculosis on human macrophage cell lines
Microb Pathog 107: 361
Kumar K, Kumar A, Keegan RM, Deshmukh R (2017)
Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease
Biomed Pharmacother 98: 297
Kumar A, Darreh-Shori T (2017)
DMSO: A Mixed-Competitive Inhibitor of Human Acetylcholinesterase
ACS Chem Neurosci 8: 2618
Kumar A, Maan P, Singh G, Kaur J (2017)
In-Silico Characterization of a Hypothetical Protein, Rv1288 of Mycobacterium tuberculosis Containing an Esterase Signature and an Uncommon LytE Domain
Curr Comput Aided Drug Des 13: 101
Parmar HS, Assaiya A, Agrawal R, Tiwari S, Mufti I, Jain N, Manivannan E, Banerjee T, Kumar A (2017)
Inhibition of Aβ(1-42)Oligomerization, Fibrillization and Acetylcholinesterase Activity by Some Anti-Inflammatory Drugs: An in vitro Study
Antiinflamm Antiallergy Agents Med Chem 15: 191
Perez-Gonzalez R, Gauthier SA, Kumar A, Saito M, Levy E (2017)
A Method for Isolation of Extracellular Vesicles and Characterization of Exosomes from Brain Extracellular Space
Methods Mol Biol 1545: 139
Rinwa P, Kumar A (2017)
Quercetin along with piperine prevents cognitive dysfunction, oxidative stress and neuro-inflammation associated with mouse model of chronic unpredictable stress
Arch Pharm Res 40: 1166
Sammi SR, Rawat JK, Raghav N, Kumar A, Roy S, Singh M, Gautam S, Yadav RK, Devi U, Pandey R, Kaithwas G (2017)
Galantamine attenuates N,N-dimethyl hydrazine induced neoplastic colon damage by inhibiting acetylcholinesterase and bimodal regulation of nicotinic cholinergic neurotransmission
European Journal of Pharmacology 818: 174
Bhardwaj M, Kumar A (2016)
Neuroprotective mechanism of Coenzyme Q10 (CoQ10) against PTZ induced kindling and associated cognitive dysfunction: Possible role of microglia inhibition
Pharmacol Rep 68: 1301
Delogu GL, Matos MJ, Fanti M, Era B, Medda R, Pieroni E, Fais A, Kumar A, Pintus F (2016)
2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling
Bioorganic & Medicinal Chemistry Lett 26: 2308
Goel A, Digvijaya, Garg A, Kumar A (2016)
Effect of Capparis spinosa Linn. extract on lipopolysaccharide-induced cognitive impairment in rats
Indian J Exp Biol 54: 126
Goomber S, Kumar A, Kaur J (2016)
Disruption of N terminus long range non covalent interactions shifted temp.opt 25 degrees C to cold: Evolution of point mutant Bacillus lipase by error prone PCR
Gene 576: 237
Goomber S, Kumar A, Singh R, Kaur J (2016)
Point Mutation Ile137-Met Near Surface Conferred Psychrophilic Behaviour and Improved Catalytic Efficiency to Bacillus Lipase of 1.4 Subfamily
Appl Biochem Biotechnol 178: 753
Khan M, Kumar A (2016)
Computational modelling and protein-ligand interaction studies of SMlipA lipase cloned from forest metagenome
J Mol Graph Model 70: 212
Kumar A, Dhar K, Kanwar SS, Arora PK (2016)
Lipase catalysis in organic solvents: advantages and applications
Biol Proced Online 18: 2
Kumar A, Sharma A, Kaur G, Makkar P, Kaur J (2016)
Functional characterization of hypothetical proteins of Mycobacterium tuberculosis with possible esterase/lipase signature: A Cumulative in silico and in vitro approach
J Biomol Struct Dyn 35: 1226
Kumar A, Aggrawal A, Pottabathini R, Singh A (2016)
Possible neuroprotective mechanisms of clove oil against icv-colchicine induced cognitive dysfunction
Pharmacol Rep 68: 764
Kumar A, Trefault N, Olaniran AO (2016)
Microbial degradation of 2,4-dichlorophenoxyacetic acid: Insight into the enzymes and catabolic genes involved, their regulation and biotechnological implications
Crit Rev Microbiol 42: 194
Rahman MA, Culsum U, Kumar A, Gao H, Hu N (2016)
Immobilization of a novel cold active esterase onto FeO approximately cellulose nano-composite enhances catalytic properties
Int J Biol Macromol 87: 488
Shukla RK, Gupta R, Srivastava P, Dhuriya YK, Singh A, Chandravanshi LP, Kumar A, Siddiqui MH, Parmar D, Pant AB, Khanna VK (2016)
Brain cholinergic alterations in rats subjected to repeated immobilization or forced swim stress on lambda-cyhalothrin exposure
Neurochem Int 93: 51
Sood A, Kumar A, Dhawan DK, Sandhir R (2016)
Propensity of Withania somnifera to Attenuate Behavioural, Biochemical, and Histological Alterations in Experimental Model of Stroke
Cellular Molecular Neurobiology 36: 1123
Arora S, Kumar A (2015)
Binary combinations of organophosphorus pesticides exhibit differential toxicity under oxidised and un-oxidised conditions
Ecotoxicology & Environmental Safety 115C: 93
Balaji B, Kumar EP, Kumar A (2015)
Evaluation of standardized Bacopa monniera extract in sodium fluoride-induced behavioural, biochemical, and histopathological alterations in mice
Toxicol Ind Health 31: 18
Kumar A, Singh A, Ekavali (2015)
A review on Alzheimer's disease pathophysiology and its management: an update
Pharmacol Rep 67: 195
Kumar A, Sharma S, Prashar A, Deshmukh R (2015)
Effect of Licofelone-A Dual COX/5-LOX Inhibitor in Intracerebroventricular Streptozotocin-Induced Behavioral and Biochemical Abnormalities in Rats
Journal of Molecular Neuroscience 55: 749
Kumar A, Jaggi AS, Singh N (2015)
Efficacy of Cilostazol a selective phosphodiesterase-3 inhibitor in rat model of Streptozotocin diabetes induced vascular dementia
Pharmacol Biochem Behav 135: 20
Kumar A, Singh B, Mishra J, Sah SP, Pottabathini R (2015)
Neuroprotective mechanism of losartan and its interaction with nimesulide against chronic fatigue stress
Inflammopharmacology 23: 291
Manda S, Sharma S, Wani A, Joshi P, Kumar V, Guru SK, Bharate SS, Bhushan S, Vishwakarma RA, Kumar A, Bharate SB (2015)
Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship
Eur Journal of Medicinal Chemistry 107: 1
Prakash A, Kalra JK, Kumar A (2015)
Neuroprotective effect of N-acetyl cysteine against streptozotocin-induced memory dysfunction and oxidative damage in rats
J Basic Clin Physiol Pharmacol 26: 13
Singh A, Kumar A (2015)
Microglial Inhibitory Mechanism of Coenzyme Q10 Against Abeta (1-42) Induced Cognitive Dysfunctions: Possible Behavioral, Biochemical, Cellular, and Histopathological Alterations
Front Pharmacol 6: 268
Tomar M, Kumar A, Kataria SK (2015)
Evaluation of Acute toxicity of Lambda Cyhalothrin in Mus musculus L
Indian J Exp Biol 53: 551
Wu G, Zhang X, Wei L, Kumar A, Mao T, Liu Z (2015)
A cold-adapted, solvent and salt tolerant esterase from marine bacterium Psychrobacter pacificensis
Int J Biol Macromol 81: 180
Are VN, Ghosh B, Kumar A, Yadav P, Bhatnagar D, Jamdar SN, Makde RD (2014)
Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans
Acta Crystallographica F Struct Biol Commun 70: 1292
Beitnere U, van Groen T, Kumar A, Jansone B, Klusa V, Kadish I (2014)
Mildronate improves cognition and reduces amyloid-beta pathology in transgenic Alzheimer's disease mice
Journal of Neuroscience Research 92: 338
Kumar A, Pillay B, Olaniran AO (2014)
Cloning, expression, purification and three-dimensional structure prediction of haloalkane dehalogenase from a recently isolated Ancylobacter aquaticus strain UV5
Protein Expr Purif 99C: 10
Kumar A, Rinwa P, Dhar H (2014)
Possible nitric oxide modulation in the protective effects of rutin against experimental head trauma-induced cognitive deficits: behavioral, biochemical, and molecular correlates
J Surg Res 188: 268
Kumar A, Rinwa P, Dhar H (2014)
Microglial inhibitory effect of ginseng ameliorates cognitive deficits and neuroinflammation following traumatic head injury in rats
Inflammopharmacology 22: 155
Kumar A, Pillay B, Olaniran AO (2014)
Two structurally different dienelactone hydrolases (TfdEI and TfdEII) from Cupriavidus necator JMP134 plasmid pJP4 catalyse cis- and trans-dienelactones with similar efficiency
PLoS ONE 9: e101801
Kumar P, Swami D, Karade HN, Acharya J, Jatav PC, Kumar A, Meena MK (2014)
In vivo protection of diisopropylphosphorofluoridate (DFP) poisoning by three bis-quaternary 2 -(hydroxyimino) -N -(pyridin-3-yl) acetamide derivatives in Swiss mice
Cellular & Molecular Biology (Noisy-le-grand) 60-3: 53
Mishra J, Chaudhary T, Kumar A (2014)
Rosiglitazone Synergizes the Neuroprotective Effects of Valproic Acid Against Quinolinic Acid-Induced Neurotoxicity in Rats: Targeting PPARgamma and HDAC Pathways
Neurotox Res 26: 130
Prakash A, Kumar A (2014)
Implicating the role of lycopene in restoration of mitochondrial enzymes and BDNF levels in beta-amyloid induced Alzheimers disease
European Journal of Pharmacology 741C: 104
Rinwa P, Kumar A (2014)
Modulation of nitrergic signalling pathway by American ginseng attenuates chronic unpredictable stress-induced cognitive impairment, neuroinflammation, and biochemical alterations
Naunyn Schmiedebergs Arch Pharmacol 387: 129
Beniwal V, Kumar A, Sharma J, Chhokar V (2013)
Recent advances in industrial application of tannases: a review
Recent Pat Biotechnol 7: 228
Kumar A, Kollath-Leiss K, Kempken F (2013)
Characterization of bud emergence 46 (BEM46) protein: Sequence, structural, phylogenetic and subcellular localization analyses
Biochemical & Biophysical Research Communications 438: 526
Saxena AK, Roy KK, Singh S, Vishnoi SP, Kumar A, Kashyap VK, Kremer L, Srivastava R, Srivastava BS (2013)
Identification and characterisation of small-molecule inhibitors of Rv3097c-encoded lipase (LipY) of Mycobacterium tuberculosis that selectively inhibit growth of bacilli in hypoxia
Int J Antimicrob Agents 42: 27
Traeger S, Altegoer F, Freitag M, Gabaldon T, Kempken F, Kumar A, Marcet-Houben M, Poggeler S, Stajich JE, Nowrousian M (2013)
The genome and development-dependent transcriptomes of Pyronema confluens: a window into fungal evolution
PLoS Genet 9: e1003820
Gaur V, Kumar A (2012)
Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury
Drug & Chemical Toxicology 35: 218
Hassan SS, Schneider MP, Ramos RT, Carneiro AR, Ranieri A, Guimaraes LC, Ali A, Bakhtiar SM, Pereira Ude P, dos Santos AR, Soares Sde C, Dorella F, Pinto AC, Ribeiro D, Barbosa MS, Almeida S, Abreu V, Aburjaile F, Fiaux K, Barbosa E, Diniz C, Rocha FS, Saxena R, Tiwari S, Zambare V, Ghosh P, Pacheco LG, Dowson CG, Kumar A, Barh D, Miyoshi A, Azevedo V, Silva A (2012)
Whole-genome sequence of Corynebacterium pseudotuberculosis strain Cp162, isolated from camel
Journal of Bacteriology 194: 5718
Rao AA, Jyothsna G, Shalini P, Kumar A, Bhattacharya A, Kashyap A (2012)
Exploring the role of BCHE in the onset of Diabetes, Obesity and Neurological Disorders
Bioinformation 8: 276
Rinwa P, Kumar A (2012)
Piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice
Brain Research 1488: 38
Kumar A, Kanwar SS (2011)
Synthesis of ethyl ferulate in organic medium using celite-immobilized lipase
Bioresour Technol 102: 2162
Kumar R, Mahajan S, Kumar A, Singh D (2011)
Identification of variables and value optimization for optimum lipase production by Bacillus pumilus RK31 using statistical methodology
N Biotechnol 28: 65
Kumar A, Prakash A, Dogra S (2011)
Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats
Pharmacol Rep 63: 915
Pandit V, Seshadri S, Rao SN, Samarasinghe C, Kumar A, Valsalan R (2011)
A case of organophosphate poisoning presenting with seizure and unavailable history of parenteral suicide attempt
J Emerg Trauma Shock 4: 132
Tabata M, Endo R, Ito M, Ohtsubo Y, Kumar A, Tsuda M, Nagata Y (2011)
The lin genes for gamma-hexachlorocyclohexane degradation in Sphingomonas sp. MM-1 proved to be dispersed across multiple plasmids
Biosci Biotechnol Biochem 75: 466
Firdoz S, Ma F, Yue X, Dai Z, Kumar A, Jiang B (2010)
A novel amperometric biosensor based on single walled carbon nanotubes with acetylcholine esterase for the detection of carbaryl pesticide in water
Talanta 83: 269
Kumar A, Dogra S, Prakash A (2010)
Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats
J Med Food 13: 976
Kumar A, Doan H, Barnes M, Chapman JC, Kookana RS (2010)
Response and recovery of acetylcholinesterase activity in freshwater shrimp, Paratya australiensis (Decapoda: Atyidae) exposed to selected anti-cholinesterase insecticides
Ecotoxicology & Environmental Safety 73: 1503
Khare SK, Kumar A, Kuo TM (2009)
Lipase-catalyzed production of a bioactive fatty amide derivative of 7,10-dihydroxy-8(E)-octadecenoic acid
Bioresour Technol 100: 1482
Kumar A, Dogra S (2009)
Neuroprotective effect of carvedilol, an adrenergic antagonist against colchicine induced cognitive impairment and oxidative damage in rat
Pharmacol Biochem Behav 92: 25
Kumar P, Kumar A (2009)
Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations
European Journal of Pharmacology 615: 91
Kumar P, Kumar A (2009)
Protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain
Indian J Exp Biol 47: 715
Prakash A, Kumar A (2009)
Effect of N-acetyl cysteine against aluminium-induced cognitive dysfunction and oxidative damage in rats
Basic Clin Pharmacol Toxicol 105: 98
Prakash AK, Kumar A (2009)
Effect of chronic treatment of carvedilol on oxidative stress in an intracerebroventricular streptozotocin induced model of dementia in rats
J Pharm Pharmacol 61: 1665
Gao Y, Kuwabara H, Spivak CE, Xiao Y, Kellar K, Ravert HT, Kumar A, Alexander M, Hilton J, Wong DF, Dannals RF, Horti AG (2008)
Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2 .1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties
Journal of Medicinal Chemistry 51: 4751
Jain M, Tilak AR, Upadhyay R, Kumar A, Mittal B (2008)
Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer
Toxicol Appl Pharmacol 230: 247
Kalonia H, Bishnoi M, Kumar A (2008)
Possible mechanism involved in sleep deprivation-induced memory dysfunction
Methods Find Exp Clin Pharmacol 30: 529
Kumar A, Deshane JS, Crossman DK, Bolisetty S, Yan BS, Kramnik I, Agarwal A, Steyn AJ (2008)
Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon
Journal of Biological Chemistry 283: 18032
Kumar A, Sehgal N, Kumar P, Padi SS, Naidu PS (2008)
Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats
Phytother Res 22: 1563
Kumar A, Naidu PS, Seghal N, Padi SS (2007)
Effect of curcumin on intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats
J Med Food 10: 486
Kumar A, Seghal N, Naidu PS, Padi SS, Goyal R (2007)
Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type
Pharmacol Rep 59: 274
Sharma P, Ahmad Shah Z, Kumar A, Islam F, Mishra KP (2007)
Role of combined administration of Tiron and glutathione against aluminum-induced oxidative stress in rat brain
J Trace Elem Med Biol 21: 63
Singh AK, Chaudhary P, Macwan AS, Diwedi UN, Kumar A (2007)
Selective loss of lin genes from hexachlorocyclohexane-degrading Pseudomonas aeruginosa ITRC-5 under different growth conditions
Applied Microbiology & Biotechnology 76: 895
Zubieta C, Krishna SS, McMullan D, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, Deller M, DiDonato M, Duan L, Elsliger MA, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Koesema E, Kumar A, Marciano D, Morse AT, Nigoghossian E, Oommachen S, Reyes R, Rife CL, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA (2007)
Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution
Proteins 68: 999
Kumar A, Seghal N, Padi SV, Naidu PS (2006)
Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats
European Journal of Pharmacology 551: 58
Ceccorulli G, Scandola M, Kumar A, Kalra B, Gross RA (2005)
Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis
Biomacromolecules 6: 902
Nagata Y, Prokop Z, Sato Y, Jerabek P, Kumar A, Ohtsubo Y, Tsuda M, Damborsky J (2005)
Degradation of beta-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26
Applied Environmental Microbiology 71: 2183
El-Merhibi A, Kumar A, Smeaton T (2004)
Role of piperonyl butoxide in the toxicity of chlorpyrifos to Ceriodaphnia dubia and Xenopus laevis
Ecotoxicology & Environmental Safety 57: 202
Kanwar YS, Pan X, Lin S, Kumar A, Wada J, Haas CS, Liau G, Lomasney JW (2003)
Imprinted mesodermal specific transcript (MEST) and H19 genes in renal development and diabetes
Kidney Int 63: 1658
Kanwar YS, Kumar A, Ota K, Lin S, Wada J, Chugh S, Wallner EI (2002)
Identification of developmentally regulated mesodermal-specific transcript in mouse embryonic metanephros
American Journal of Physiology Renal Physiol 282: F953
Kumar A, Agarwal S, Heyman JA, Matson S, Heidtman M, Piccirillo S, Umansky L, Drawid A, Jansen R, Liu Y, Cheung KH, Miller P, Gerstein M, Roeder GS, Snyder M (2002)
Subcellular localization of the yeast proteome
Genes Dev 16: 707
Woods M, Kumar A, Correll R (2002)
Acute toxicity of mixtures of chlorpyrifos, profenofos, and endosulfan to Ceriodaphnia dubia
Bulletin of Environmental Contamination & Toxicology 68: 801
Kumar A, Chapman JC (2001)
Profenofos residues in wild fish from cotton-growing areas of New South Wales, Australia
J Environ Qual 30: 740
Kumar A, Gross RA, Jendrossek D (2000)
Poly(3-hydroxybutyrate)-depolymerase from Pseudomonas lemoignei: catalysis of esterifications in organic media
J Org Chem 65: 7800
Kumar A, Gross RA (2000)
Candida antartica lipase B catalyzed polycaprolactone synthesis: effects of organic media and temperature
Biomacromolecules 1: 133
Schliebs R, Liebmann A, Bhattacharya SK, Kumar A, Ghosal S, Bigl V (1997)
Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain
Neurochem Int 30: 181
Rossner S, Kumar A, Witzemann V, Schliebs R (1994)
Development of laminar expression of the m2 muscarinic cholinergic receptor gene in rat visual cortex and the effect of monocular visual deprivation
Brain Research Developmental Brain Research 77: 55
Ansari MZ, Kumar A, Prasad RL, Basu A, Sahai BN, Sinha AP (1990)
Clinico-biochemical use of serum acetylcholine esterase following treatment with synthetic pyrethroids, cypermethrin and fenvalerate, in cattle and buffalo experimentally infested with Boophilus microplus
Indian J Exp Biol 28: 241