Knez D, Diez-Iriepa D, Chioua M, Gottinger A, Denic M, Chantegreil F, Nachon F, Brazzolotto X, Skrzypczak-Wiercioch A, Meden A, Pislar A, Kos J, Zakelj S, Stojan J, Salat K, Serrano J, Patricia Fernandez AP, Sanchez-Garcia A, Martinez-Murillo R, Binda C, Lopez-Munoz F, Gobec S, Marco-Contelle J (2023)
8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases
Acta Pharmaceutica Sinica B 13: 2152

Kos J, Mitrovic A, Perisic Nanut M, Pislar A (2022)
Lysosomal peptidases - Intriguing roles in cancer progression and neurodegeneration
FEBS Open Bio

Kos J, Kozik V, Pindjakova D, Jankech T, Smolinski A, Stepankova S, Hosek J, Oravec M, Jampilek J, Bak A (2021)
Synthesis and Hybrid SAR Property Modeling of Novel Cholinesterase Inhibitors
Int J Mol Sci 22:

Kosak U, Strasek N, Knez N, Jukic M, Zakelj S, Zahirovic A, Pislar A, Brazzolotto X, Nachon F, Kos J, Gobec S, Knez D (2020)
N-alkylpiperidine carbamates as potential anti-Alzheimer's agents
Eur Journal of Medicinal Chemistry 197: 112282

Bak A, Pizova H, Kozik V, Vorcakova K, Kos J, Treml J, Odehnalova K, Oravec M, Imramovsky A, Bobal P, Smolinski A, Travnicek Z, Jampilek J (2019)
SAR-mediated Similarity Assessment of the Property Profile for New, Silicon-Based AChE/BChE Inhibitors
Int J Mol Sci 20: 5385

Knez D, Sosic I, Pislar A, Mitrovic A, Jukic M, Kos J, Gobec S (2019)
Biological Evaluation of 8-Hydroxyquinolines as Multi-Target Directed Ligands for Treating Alzheimer's Disease
Curr Alzheimer Res 16: 801

Meden A, Knez D, Jukic M, Brazzolotto X, Grsic M, Pislar A, Zahirovic A, Kos J, Nachon F, Svete J, Gobec S, Groselj U (2019)
Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease
Chem Commun (Camb) 55: 3765

Knez D, Coquelle N, Pislar A, Zakelj S, Jukic M, Sova M, Mravljak J, Nachon F, Brazzolotto X, Kos J, Colletier JP, Gobec S (2018)
Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities
Eur Journal of Medicinal Chemistry 156: 598

Kosak U, Brus B, Knez D, Zakelj S, Trontelj J, Pislar A, Sink R, Jukic M, Zivin M, Podkowa A, Nachon F, Brazzolotto X, Stojan J, Kos J, Coquelle N, Salat K, Colletier JP, Gobec S (2018)
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity
Journal of Medicinal Chemistry 61: 119

Panek D, Wieckowska A, Jonczyk J, Godyn J, Bajda M, Wichur T, Pasieka A, Knez D, Pislar A, Korabecny J, Soukup O, Sepsova V, Sabate R, Kos J, Gobec S, Malawska B (2018)
Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents
ACS Chem Neurosci 9: 1074

Kosak U, Knez D, Coquelle N, Brus B, Pislar A, Nachon F, Brazzolotto X, Kos J, Colletier JP, Gobec S (2017)
N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents
Bioorganic & Medicinal Chemistry 25: 633

Kosak U, Brus B, Knez D, Sink R, Zakelj S, Trontelj J, Pislar A, Slenc J, Gobec M, Zivin M, Tratnjek L, Perse M, Salat K, Podkowa A, Filipek B, Nachon F, Brazzolotto X, Wieckowska A, Malawska B, Stojan J, Rascan IM, Kos J, Coquelle N, Colletier JP, Gobec S (2016)
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
Sci Rep 6: 39495

Guzior N, Bajda M, Skrok M, Kurpiewska K, Lewinski K, Brus B, Pislar A, Kos J, Gobec S, Malawska B (2015)
Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and beta-amyloid aggregation inhibitors with neuroprotective properties
Eur Journal of Medicinal Chemistry 92C: 738

Brus B, Kosak U, Turk S, Pislar A, Coquelle N, Kos J, Stojan J, Colletier JP, Gobec S (2014)
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor
Journal of Medicinal Chemistry 57: 8167