Koller M, Thiermann H, Worek F, Wille T (2021)
Release of protein-bound nerve agents by excess fluoride from whole blood: GC-MS/MS method development, validation, and application to a real-life denatured blood sample
Journal of Chromatography B Analyt Technol Biomed Life Sciences 1179: 122693
Stigler L, Kohler A, Koller M, Job L, Escher B, Potschka H, Thiermann H, Skerra A, Worek F, Wille T (2021)
Post-VX exposure treatment of rats with engineered phosphotriesterases
Archives of Toxicology
Amend N, Langgartner J, Siegert M, Kranawetvogl T, Koller M, John H, Pflugler C, Mogele-Schmid C, Worek F, Thiermann H, Wille T (2020)
A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making
Archives of Toxicology
Worek F, Thiermann H, Koller M, Wille T (2020)
In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase
Molecules 25:
John H, van der Schans MJ, Koller M, Spruit HET, Worek F, Thiermann H, Noort D (2018)
Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network
Forensic Toxicol 36: 61
Wille T, Neumaier K, Koller M, Ehinger C, Aggarwal N, Ashani Y, Goldsmith M, Sussman JL, Tawfik DS, Thiermann H, Worek F (2016)
Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection
Toxicol Lett 258: 198
Worek F, Koller M, Thiermann H, Wille T (2016)
Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics
Toxicology 350-352: 25
Worek F, Herkert NM, Koller M, Thiermann H, Wille T (2015)
Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes
Toxicol In Vitro 30: 514
Worek F, Elsinghorst P, Koller M, Thiermann H (2014)
Reactions of methylphosphonic difluoride with human acetylcholinesterase and oximes - Possible therapeutic implications
Toxicol Lett 231: 92
Worek F, Wille T, Koller M, Thiermann H (2013)
Structural requirements for effective oximes - Evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes
Chemico-Biological Interactions 203: 125
Bogan R, Koller M, Klaubert B (2012)
Purity of antidotal oxime HI-6 DMS as an active pharmaceutical ingredient for auto-injectors and infusions
Drug Test Anal 4: 199
Bogan R, Worek F, Koller M, Klaubert B (2012)
Photostability of antidotal oxime HI-6, impact on drug development
Drug Test Anal 4: 208
Worek F, Wille T, Koller M, Thiermann H (2012)
Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships
Biochemical Pharmacology 83: 1700
Muller S, Koller M, Le Provost R, Lafont O, Estour F, Wille T, Thiermann H, Worek F, Reiter G (2011)
In vitro detoxification of cyclosarin (GF) by modified cyclodextrins
Toxicol Lett 200: 53
Aurbek N, Herkert NM, Koller M, Thiermann H, Worek F (2010)
Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
Chemico-Biological Interactions 187: 215
Koller M, Becker C, Thiermann H, Worek F (2010)
GC-MS and LC-MS analysis of nerve agents in body fluids: intra-laboratory verification test using spiked plasma and urine samples
Journal of Chromatography B Analyt Technol Biomed Life Sciences 878: 1226
Melzer M, Chen JC, Heidenreich A, Gab J, Koller M, Kehe K, Blum MM (2009)
Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design
J Am Chem Soc 131: 17226
Worek F, Herkert NM, Koller M, Aurbek N, Thiermann H (2009)
Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study
Toxicol Lett 187: 119
Worek F, Aurbek N, Koller M, Becker C, Eyer P, Thiermann H (2007)
Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates
Biochemical Pharmacology 73: 1807
Worek F, Koller M, Thiermann H, Szinicz L (2005)
Diagnostic aspects of organophosphate poisoning
Toxicology 214: 182