Schemenauer DE, Pool EH, Raynor SN, Ruiz GP, Goehring LM, Koelper AJ, Wilson MA, Durand AJ, Jr., Kourtoglou EC, Larsen EM, Lavis LD, Esteb JJ, Hoops GC, Johnson RJ (2023)
Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN
ACS Omega 8: 13252

Bowles IE, Pool EH, Lancaster BS, Lawson EK, Savas CP, Kartje ZJ, Severinac L, Cho DH, Macbeth MR, Johnson RJ, Hoops GC (2021)
Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C
Protein Science

Miller JJ, Shah IT, Hatten J, Barekatain Y, Mueller EA, Moustafa AM, Edwards RL, Dowd CS, Hoops GC, Johnson RJ, Planet PJ, Muller FL, Jez JM, Odom John AR (2021)
Structure-guided microbial targeting of antistaphylococcal prodrugs
Elife 10:

Bun JS, Slack MD, Schemenauer DE, Johnson RJ (2020)
Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae
PLoS ONE 15: e0230166

Larsen EM, Johnson RJ (2019)
Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance
Drug Dev Res 80: 33

Bassett B, Waibel B, White A, Hansen H, Stephens D, Koelper A, Larsen EM, Kim C, Glanzer A, Lavis LD, Hoops GC, Johnson RJ (2018)
Measuring the Global Substrate Specificity of Mycobacterial Serine Hydrolases Using a Library of Fluorogenic Ester Substrates
ACS Infect Dis 4: 904

Smith MA, Phillips WK, Rabin PL, Johnson RJ (2018)
A dynamic loop provides dual control over the catalytic and membrane binding activity of a bacterial serine hydrolase
Biochimica & Biophysica Acta 1866: 925

White A, Koelper A, Russell A, Larsen EM, Kim C, Lavis LD, Hoops GC, Johnson RJ (2018)
Fluorogenic structure activity library pinpoints molecular variations in substrate specificity of structurally homologous esterases
Journal of Biological Chemistry 293: 13851

Dube S, Dube H, Green NB, Larsen EM, White A, Johnson RJ, Kowalski JR (2017)
In Vivo Delivery and Activation of Masked Fluorogenic Hydrolase Substrates by Endogenous Hydrolases in C. elegans
Chembiochem 18: 1807

Farberg AM, Hart WK, Johnson RJ (2016)
The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis
Biochem Biophys Rep 7: 415

McKary MG, Abendroth J, Edwards TE, Johnson RJ (2016)
Structural Basis for the Strict Substrate Selectivity of the Mycobacterial Hydrolase LipW
Biochemistry 55: 7099

Lukowski JK, Savas CP, Gehring AM, McKary MG, Adkins CT, Lavis LD, Hoops GC, Johnson RJ (2014)
Distinct Substrate Selectivity of a Metabolic Hydrolase from Mycobacterium tuberculosis
Biochemistry 53: 7386

Ellis EE, Adkins CT, Galovska NM, Lavis LD, Johnson RJ (2013)
Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase
Chembiochem 14: 1134

Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L, Winsor JR, Lavis LD, Satchell KJ, Becker DP, Anderson WF, Johnson RJ (2013)
Large-scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis
Journal of Biological Chemistry 288: 10522

Hedge MK, Gehring AM, Adkins CT, Weston LA, Lavis LD, Johnson RJ (2012)
The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima
Biochimica & Biophysica Acta 1824: 1024