Schemenauer DE, Pool EH, Raynor SN, Ruiz GP, Goehring LM, Koelper AJ, Wilson MA, Durand AJ, Jr., Kourtoglou EC, Larsen EM, Lavis LD, Esteb JJ, Hoops GC, Johnson RJ (2023) <br />Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN<br /><i>ACS Omega</i> <b>8</b>: 13252<br /><br />Bowles IE, Pool EH, Lancaster BS, Lawson EK, Savas CP, Kartje ZJ, Severinac L, Cho DH, Macbeth MR, Johnson RJ, Hoops GC (2021) <br />Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C<br /><i>Protein Science</i> <br /><br />Miller JJ, Shah IT, Hatten J, Barekatain Y, Mueller EA, Moustafa AM, Edwards RL, Dowd CS, Hoops GC, Johnson RJ, Planet PJ, Muller FL, Jez JM, Odom John AR (2021) <br />Structure-guided microbial targeting of antistaphylococcal prodrugs<br /><i>Elife</i> <b>10</b>: <br /><br />Bun JS, Slack MD, Schemenauer DE, Johnson RJ (2020) <br />Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae<br /><i>PLoS ONE</i> <b>15</b>: e0230166<br /><br />Larsen EM, Johnson RJ (2019) <br />Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance<br /><i>Drug Dev Res</i> <b>80</b>: 33<br /><br />Bassett B, Waibel B, White A, Hansen H, Stephens D, Koelper A, Larsen EM, Kim C, Glanzer A, Lavis LD, Hoops GC, Johnson RJ (2018) <br />Measuring the Global Substrate Specificity of Mycobacterial Serine Hydrolases Using a Library of Fluorogenic Ester Substrates<br /><i>ACS Infect Dis</i> <b>4</b>: 904<br /><br />Smith MA, Phillips WK, Rabin PL, Johnson RJ (2018) <br />A dynamic loop provides dual control over the catalytic and membrane binding activity of a bacterial serine hydrolase<br /><i>Biochimica & Biophysica Acta</i> <b>1866</b>: 925<br /><br />White A, Koelper A, Russell A, Larsen EM, Kim C, Lavis LD, Hoops GC, Johnson RJ (2018) <br />Fluorogenic structure activity library pinpoints molecular variations in substrate specificity of structurally homologous esterases<br /><i>Journal of Biological Chemistry</i> <b>293</b>: 13851<br /><br />Dube S, Dube H, Green NB, Larsen EM, White A, Johnson RJ, Kowalski JR (2017) <br />In Vivo Delivery and Activation of Masked Fluorogenic Hydrolase Substrates by Endogenous Hydrolases in C. elegans<br /><i>Chembiochem</i> <b>18</b>: 1807<br /><br />Farberg AM, Hart WK, Johnson RJ (2016) <br />The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis<br /><i>Biochem Biophys Rep</i> <b>7</b>: 415<br /><br />McKary MG, Abendroth J, Edwards TE, Johnson RJ (2016) <br />Structural Basis for the Strict Substrate Selectivity of the Mycobacterial Hydrolase LipW<br /><i>Biochemistry</i> <b>55</b>: 7099<br /><br />Lukowski JK, Savas CP, Gehring AM, McKary MG, Adkins CT, Lavis LD, Hoops GC, Johnson RJ (2014) <br />Distinct Substrate Selectivity of a Metabolic Hydrolase from Mycobacterium tuberculosis<br /><i>Biochemistry</i> <b>53</b>: 7386<br /><br />Ellis EE, Adkins CT, Galovska NM, Lavis LD, Johnson RJ (2013) <br />Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase<br /><i>Chembiochem</i> <b>14</b>: 1134<br /><br />Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L, Winsor JR, Lavis LD, Satchell KJ, Becker DP, Anderson WF, Johnson RJ (2013) <br />Large-scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis<br /><i>Journal of Biological Chemistry</i> <b>288</b>: 10522<br /><br />Hedge MK, Gehring AM, Adkins CT, Weston LA, Lavis LD, Johnson RJ (2012) <br />The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima<br /><i>Biochimica & Biophysica Acta</i> <b>1824</b>: 1024<br /><br />