Allgardsson A, Berg L, Akfur C, Hornberg A, Worek F, Linusson A, Ekstrom F (2016) <br />Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6<br /><i>Proc Natl Acad Sci U S A</i> <b>113</b>: 5514<br /><br />Berg L, Andersson CD, Artursson E, Hornberg A, Tunemalm AK, Linusson A, Ekstrom F (2011) <br />Targeting acetylcholinesterase: identification of chemical leads by high throughput screening, structure determination and molecular modeling<br /><i>PLoS ONE</i> <b>6</b>: e26039<br /><br />Hornberg A, Artursson E, Warme R, Pang YP, Ekstrom F (2010) <br />Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad<br /><i>Biochemical Pharmacology</i> <b>79</b>: 507<br /><br />Artursson E, Akfur C, Hornberg A, Worek F, Ekstrom F (2009) <br />Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis<br /><i>Toxicology</i> <b>265</b>: 108<br /><br />Ekstrom F, Hornberg A, Artursson E, Hammarstrom LG, Schneider G, Pang YP (2009) <br />Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design<br /><i>PLoS ONE</i> <b>4</b>: e5957<br /><br />Hornberg A, Tunemalm AK, Ekstrom F (2007) <br />Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state<br /><i>Biochemistry</i> <b>46</b>: 4815<br /><br />