Kiss-Szeman AJ, Straner P, Jakli I, Hosogi N, Harmat V, Menyhard DK, Perczel A (2022) <br />Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad<br /><i>Chem Sci</i> <b>13</b>: 7132<br /><br />Kiss-Szeman AJ, Takacs L, Orgovan Z, Straner P, Jakli I, Schlosser G, Masiulis S, Harmat V, Menyhard DK, Perczel A (2022) <br />A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase-meropenem complex<br /><i>Chem Sci</i> <b>13</b>: 14264<br /><br />Kiss-Szeman AJ, Harmat V, Menyhard DK (2019) <br />Achieving Functionality Through Modular Build-up: Structure and Size Selection of Serine Oligopeptidases<br /><i>Curr Protein Pept Sci</i> <b>20</b>: 1089<br /><br />Menyhard DK, Orgovan Z, Szeltner Z, Szamosi I, Harmat V (2015) <br />Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality<br /><i>Acta Crystallographica D Biol Crystallogr</i> <b>71</b>: 461<br /><br />Menyhard DK, Kiss-Szeman A, Tichy-Racs E, Hornung B, Radi K, Szeltner Z, Domokos K, Szamosi I, Naray-Szabo G, Polgar L, Harmat V (2013) <br />A self-compartmentalizing hexamer serine protease from Pyrococcus horikoshii: substrate selection achieved through multimerization<br /><i>Journal of Biological Chemistry</i> <b>288</b>: 17884<br /><br />Harmat V, Domokos K, Menyhard DK, Pallo A, Szeltner Z, Szamosi I, Beke-Somfai T, Naray-Szabo G, Polgar L (2011) <br />Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase<br /><i>Journal of Biological Chemistry</i> <b>286</b>: 1987<br /><br />Szeltner Z, Kiss AL, Domokos K, Harmat V, Naray-Szabo G, Polgar L (2009) <br />Characterization of a novel acylaminoacyl peptidase with hexameric structure and endopeptidase activity<br /><i>Biochimica & Biophysica Acta</i> <b>1794</b>: 1204<br /><br />Kannai K, Aranyi P, Bocskei Z, Ferenczy G, Harmat V, Simon K, Batori S, Naray-Szabo G, Hermecz I (2008) <br />Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules<br /><i>Journal of Medicinal Chemistry</i> <b>51</b>: 7514<br /><br />Kiss AL, Pallo A, Naray-Szabo G, Harmat V, Polgar L (2008) <br />Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase<br /><i>J Struct Biol</i> <b>162</b>: 312<br /><br />Kiss AL, Hornung B, Radi K, Gengeliczki Z, Sztaray B, Juhasz T, Szeltner Z, Harmat V, Polgar L (2007) <br />The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity<br /><i>Journal of Molecular Biology</i> <b>368</b>: 509<br /><br />