McGarry KG, Lalisse RF, Moyer RA, Johnson KM, Tallan AM, Winters TP, Taris JE, McElroy CA, Lemmon EE, Shafaat HS, Fan Y, Deal A, Marguet SC, Harvilchuck JA, Hadad CM, Wood DW (2020)
A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin
Toxicol Sci 174: 133

Franjesevic AJ, Sillart SB, Beck JM, Vyas S, Callam CS, Hadad CM (2019)
Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase
Chemistry 25: 5337

Zhuang Q, Franjesevic AJ, Corrigan TS, Coldren WH, Dicken R, Sillart S, DeYong A, Yoshino N, Smith J, Fabry S, Fitzpatrick K, Blanton TG, Joseph J, Yoder RJ, McElroy CA, Ekici OD, Callam CS, Hadad CM (2018)
Demonstration of In Vitro Resurrection of Aged Acetylcholinesterase after Exposure to Organophosphorus Chemical Nerve Agents
Journal of Medicinal Chemistry 61: 7034

Yoder RJ, Zhuang Q, Beck JM, Franjesevic AJ, Blanton TG, Sillart S, Secor T, Guerra L, Brown JD, Reid C, McElroy CA, Dogan Ekici O, Callam CS, Hadad CM (2017)
Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase
ACS Med Chem Lett 8: 622

Zhuang Q, Young A, Callam CS, McElroy CA, Ekici OD, Yoder RJ, Hadad CM (2016)
Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase
Annals of the New York Academy of Sciences 1374: 94

Muthukrishnan S, Shete VS, Sanan TT, Vyas S, Oottikkal S, Porter LM, Magliery TJ, Hadad CM (2012)
Mechanistic Insights into the Hydrolysis of Organophosphorus Compounds by Paraoxonase-1: Exploring the Limits of Substrate Tolerance in a Promiscuous Enzyme
J Phys Org Chem 25: 1247

Beck JM, Hadad CM (2010)
Reaction profiles of the interaction between sarin and acetylcholinesterase and the S203C mutant: model nucleophiles and QM/MM potential energy surfaces
Chemico-Biological Interactions 187: 220

Rieth S, Bao X, Wang BY, Hadad CM, Badjic JD (2010)
Gated molecular recognition and dynamic discrimination of guests
Journal of the American Chemical Society 132: 773

Sanan TT, Muthukrishnan S, Beck JM, Tao P, Hayes CJ, Otto TC, Cerasoli DM, Lenz DE, Hadad CM (2010)
Computational Modeling of Human Paraoxonase 1: Preparation of Protein Models, Binding Studies, and Mechanistic Insights
J Phys Org Chem 23: 357

Vyas S, Beck JM, Xia S, Zhang J, Hadad CM (2010)
Butyrylcholinesterase and G116H, G116S, G117H, G117N, E197Q and G117H/E197Q mutants: a molecular dynamics study
Chemico-Biological Interactions 187: 241

Barakat NH, Zheng X, Gilley CB, MacDonald M, Okolotowicz K, Cashman JR, Vyas S, Beck JM, Hadad CM, Zhang J (2009)
Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase
Chemical Research in Toxicology 22: 1669

Beck JM, Hadad CM (2008)
Hydrolysis of nerve agents by model nucleophiles: a computational study
Chemico-Biological Interactions 175: 200

Vyas S, Hadad CM (2008)
Reactivation of model cholinesterases by oximes and intermediate phosphyloximes: a computational study
Chemico-Biological Interactions 175: 187