McGarry KG, Lalisse RF, Moyer RA, Johnson KM, Tallan AM, Winters TP, Taris JE, McElroy CA, Lemmon EE, Shafaat HS, Fan Y, Deal A, Marguet SC, Harvilchuck JA, Hadad CM, Wood DW (2020) <br />A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin<br /><i>Toxicol Sci</i> <b>174</b>: 133<br /><br />Franjesevic AJ, Sillart SB, Beck JM, Vyas S, Callam CS, Hadad CM (2019) <br />Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase<br /><i>Chemistry</i> <b>25</b>: 5337<br /><br />Zhuang Q, Franjesevic AJ, Corrigan TS, Coldren WH, Dicken R, Sillart S, DeYong A, Yoshino N, Smith J, Fabry S, Fitzpatrick K, Blanton TG, Joseph J, Yoder RJ, McElroy CA, Ekici OD, Callam CS, Hadad CM (2018) <br />Demonstration of In Vitro Resurrection of Aged Acetylcholinesterase after Exposure to Organophosphorus Chemical Nerve Agents<br /><i>Journal of Medicinal Chemistry</i> <b>61</b>: 7034<br /><br />Yoder RJ, Zhuang Q, Beck JM, Franjesevic AJ, Blanton TG, Sillart S, Secor T, Guerra L, Brown JD, Reid C, McElroy CA, Dogan Ekici O, Callam CS, Hadad CM (2017) <br />Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase<br /><i>ACS Med Chem Lett</i> <b>8</b>: 622<br /><br />Zhuang Q, Young A, Callam CS, McElroy CA, Ekici OD, Yoder RJ, Hadad CM (2016) <br />Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase<br /><i>Annals of the New York Academy of Sciences</i> <b>1374</b>: 94<br /><br />Muthukrishnan S, Shete VS, Sanan TT, Vyas S, Oottikkal S, Porter LM, Magliery TJ, Hadad CM (2012) <br />Mechanistic Insights into the Hydrolysis of Organophosphorus Compounds by Paraoxonase-1: Exploring the Limits of Substrate Tolerance in a Promiscuous Enzyme<br /><i>J Phys Org Chem</i> <b>25</b>: 1247<br /><br />Beck JM, Hadad CM (2010) <br />Reaction profiles of the interaction between sarin and acetylcholinesterase and the S203C mutant: model nucleophiles and QM/MM potential energy surfaces<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 220<br /><br />Rieth S, Bao X, Wang BY, Hadad CM, Badjic JD (2010) <br />Gated molecular recognition and dynamic discrimination of guests<br /><i>Journal of the American Chemical Society</i> <b>132</b>: 773<br /><br />Sanan TT, Muthukrishnan S, Beck JM, Tao P, Hayes CJ, Otto TC, Cerasoli DM, Lenz DE, Hadad CM (2010) <br />Computational Modeling of Human Paraoxonase 1: Preparation of Protein Models, Binding Studies, and Mechanistic Insights<br /><i>J Phys Org Chem</i> <b>23</b>: 357<br /><br />Vyas S, Beck JM, Xia S, Zhang J, Hadad CM (2010) <br />Butyrylcholinesterase and G116H, G116S, G117H, G117N, E197Q and G117H/E197Q mutants: a molecular dynamics study<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 241<br /><br />Barakat NH, Zheng X, Gilley CB, MacDonald M, Okolotowicz K, Cashman JR, Vyas S, Beck JM, Hadad CM, Zhang J (2009) <br />Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase<br /><i>Chemical Research in Toxicology</i> <b>22</b>: 1669<br /><br />Beck JM, Hadad CM (2008) <br />Hydrolysis of nerve agents by model nucleophiles: a computational study<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 200<br /><br />Vyas S, Hadad CM (2008) <br />Reactivation of model cholinesterases by oximes and intermediate phosphyloximes: a computational study<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 187<br /><br />