Grinan-Ferre C, Jarne-Ferrer J, Bellver-Sanchis A, Codony S, Puigoriol-Illamola D, Sanfeliu C, Oh Y, Lee S, Vazquez S, Pallas M (2023)
Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics
CNS Neurosci Ther

Bartra C, Irisarri A, Villoslada A, Corpas R, Aguirre S, Garcia-Lara E, Sunol C, Pallas M, Grinan-Ferre C, Sanfeliu C (2022)
Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer's Disease Neurodegeneration
Int J Mol Sci 23:

Codony S, Pont C, Grinan-Ferre C, Di Pede-Mattatelli A, Calvo-Tusell C, Feixas F, Osuna S, Jarne-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Perez B, Bartra C, Sanfeliu C, Juarez-Jimenez J, Morisseau C, Hammock BD, Pallas M, Vazquez S, Munoz-Torrero D (2022)
Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Journal of Medicinal Chemistry 65: 4909

Codony S, Entrena JM, Calvo-Tusell C, Jora B, Gonzalez-Cano R, Osuna S, Corpas R, Morisseau C, Perez B, Barniol-Xicota M, Grinan-Ferre C, Perez C, Rodriguez-Franco MI, Martinez AL, Loza MI, Pallas M, Verhelst SHL, Sanfeliu C, Feixas F, Hammock BD, Brea J, Cobos EJ, Vazquez S (2022)
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Journal of Medicinal Chemistry 65: 13660

Jarne-Ferrer J, Grinan-Ferre C, Bellver-Sanchis A, Vazquez S, Munoz-Torrero D, Pallas M (2022)
A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer's Disease Mice Models
Pharmaceuticals (Basel) 15:

Codony S, Calvo-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Perez C, Rodriguez-Franco MI, Pizarro-Delgado J, Corpas R, Grinan-Ferre C, Pallas M, Sanfeliu C, Vazquez-Carrera M, Hammock BD, Feixas F, Vazquez S (2021)
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Journal of Medicinal Chemistry

Grinan-Ferre C, Companys-Alemany J, Jarne-Ferrer J, Codony S, Gonzalez-Castillo C, Ortuno-Sahagun D, Vilageliu L, Grinberg D, Vazquez S, Pallas M (2021)
Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease
Int J Mol Sci 22:

Pont C, Ginex T, Grinan-Ferre C, Scheiner M, Mattellone A, Martinez N, Arce EM, Soriano-Fernandez Y, Naldi M, De Simone A, Barenys M, Gomez-Catalan J, Perez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallas M, Luque FJ, Munoz-Torrero D (2021)
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Eur Journal of Medicinal Chemistry 225: 113779

Vasilopoulou F, Rodriguez-Arevalo S, Bagan A, Escolano C, Grinan-Ferre C, Pallas M (2021)
Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: A Comparative study with donepezil
British Journal of Pharmacology

Grinan-Ferre C, Codony S, Pujol E, Yang J, Leiva R, Escolano C, Puigoriol-Illamola D, Companys-Alemany J, Corpas R, Sanfeliu C, Perez B, Loza MI, Brea J, Morisseau C, Hammock BD, Vazquez S, Pallas M, Galdeano C (2020)
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
Neurotherapeutics

Pallas M, Vazquez S, Sanfeliu C, Galdeano C, Grinan-Ferre C (2020)
Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy
Biomolecules 10: