Vazquez J, Ginex T, Herrero A, Morisseau C, Hammock BD, Luque FJ (2023)
Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits
J Chem Inf Model
Hofmann J, Ginex T, Espargaro A, Scheiner M, Gunesch S, Arago M, Stigloher C, Sabate R, Luque FJ, Decker M (2021)
Azobioisosteres of Curcumin with Pronounced Activity against Amyloid Aggregation, Intracellular Oxidative Stress, and Neuroinflammation
Chemistry 27: 6015
Pont C, Ginex T, Grinan-Ferre C, Scheiner M, Mattellone A, Martinez N, Arce EM, Soriano-Fernandez Y, Naldi M, De Simone A, Barenys M, Gomez-Catalan J, Perez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallas M, Luque FJ, Munoz-Torrero D (2021)
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Eur Journal of Medicinal Chemistry 225: 113779
Perez-Areales FJ, Garrido M, Aso E, Bartolini M, De Simone A, Espargaro A, Ginex T, Sabate R, Perez B, Andrisano V, Puigoriol-Illamola D, Pallas M, Luque FJ, Loza MI, Brea J, Ferrer I, Ciruela F, Messeguer A, Munoz-Torrero D (2020)
Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry 63: 9360
Sonmez F, Zengin Kurt B, Gazioglu I, Basile L, Dag A, Cappello V, Ginex T, Kucukislamoglu M, Guccione S (2017)
Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors
J Enzyme Inhib Med Chem 32: 285
Kurt BZ, Gazioglu I, Basile L, Sonmez F, Ginex T, Kucukislamoglu M, Guccione S (2015)
Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease
Eur Journal of Medicinal Chemistry 102: 80