Meyer WK, Jamison J, Richter R, Woods SE, Partha R, Kowalczyk A, Kronk C, Chikina M, Bonde RK, Crocker DE, Gaspard J, Lanyon JM, Marsillach J, Furlong CE, Clark NL (2018)
Ancient convergent losses of Paraoxonase 1 yield potential risks for modern marine mammals
Science 361: 591

Furlong CE, Marsillach J, Jarvik GP, Costa LG (2016)
Paraoxonases-1, -2 and -3: What are their functions?
Chemico-Biological Interactions 259: 51

Garrick JM, Dao K, de Laat R, Elsworth J, Cole TB, Marsillach J, Furlong CE, Costa LG (2016)
Developmental expression of paraoxonase 2
Chemico-Biological Interactions 259: 168

Souza-Nogueira A, Camargo AE, Remondi FA, Paoliello MM, Richter RJ, Furlong CE, Barbosa DS, Maes M, Moreira EG (2016)
Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score
Arch Endocrinol Metab 60: 426

Cole TB, Li WF, Co AL, Hay AM, MacDonald JW, Bammler TK, Farin FM, Costa LG, Furlong CE (2014)
Repeated Gestational Exposure of Mice to Chlorpyrifos Oxon Is Associated with Paraoxonase 1 (PON1) Modulated Effects in Maternal and Fetal Tissues
Toxicol Sci 141: 409

Costa LG, de Laat R, Dao K, Pellacani C, Cole TB, Furlong CE (2014)
Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection
Neurotoxicology 43: 3

Kim DS, Crosslin DR, Auer PL, Suzuki SM, Marsillach J, Burt AA, Gordon AS, Meschia JF, Nalls MA, Worrall BB, Longstreth WT, Jr., Gottesman RF, Furlong CE, Peters U, Rich SS, Nickerson DA, Jarvik GP (2014)
Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project
J Lipid Res 55: 1173

Marsillach J, Suzuki SM, Richter RJ, McDonald MG, Rademacher PM, Maccoss MJ, Hsieh EJ, Rettie AE, Furlong CE (2014)
Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase
PLoS ONE 9: e110054

Baker PE, Cole TB, Cartwright M, Suzuki SM, Thummel KE, Lin YS, Co AL, Rettie AE, Kim JH, Furlong CE (2013)
Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants
Chemico-Biological Interactions 203: 257

Chen W, Kim JH, Zhang D, Lee KH, Cangelosi GA, Soelberg SD, Furlong CE, Chung JH, Shen AQ (2013)
Microfluidic one-step synthesis of alginate microspheres immobilized with antibodies
J R Soc Interface 10: 20130566

Costa LG, Giordano G, Cole TB, Marsillach J, Furlong CE (2013)
Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity
Toxicology 307: 115

Costa LG, Tait L, de Laat R, Dao K, Giordano G, Pellacani C, Cole TB, Furlong CE (2013)
Modulation of Paraoxonase 2 (PON2) in Mouse Brain by the Polyphenol Quercetin: A Mechanism of Neuroprotection?
Neurochem Res 38: 1809

Giordano G, Tait L, Furlong CE, Cole TB, Kavanagh TJ, Costa LG (2013)
Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression
Free Radic Biol Med 58: 98

Kim DS, Burt AA, Crosslin DR, Robertson PD, Ranchalis JE, Boyko EJ, Nickerson DA, Furlong CE, Jarvik GP (2013)
Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL
J Lipid Res 54: 552

Kim DS, Burt AA, Ranchalis JE, Jarvik ER, Rosenthal EA, Hatsukami TS, Furlong CE, Jarvik GP (2013)
Novel gene-by-environment interactions: APOB and NPC1L1 variants affect the relationship between dietary and total plasma cholesterol
J Lipid Res 54: 1512

Kim DS, Maden SK, Burt AA, Ranchalis JE, Furlong CE, Jarvik GP (2013)
Dietary fatty acid intake is associated with paraoxonase 1 activity in a cohort-based analysis of 1,548 subjects
Lipids Health Dis 12: 183

Kim DS, Marsillach J, Furlong CE, Jarvik GP (2013)
Pharmacogenetics of paraoxonase activity: elucidating the role of high-density lipoprotein in disease
Pharmacogenomics 14: 1495

Marsillach J, Hsieh EJ, Richter RJ, Maccoss MJ, Furlong CE (2013)
Proteomic analysis of adducted butyrylcholinesterase for biomonitoring organophosphorus exposures
Chemico-Biological Interactions 203: 85

Marsillach J, Costa LG, Furlong CE (2013)
Protein adducts as biomarkers of exposure to organophosphorus compounds
Toxicology 307: 46

Cole TB, Fisher JC, Burbacher TM, Costa LG, Furlong CE (2012)
Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon
Neurotoxicology & Teratology 34: 311

Kim DS, Burt AA, Ranchalis JE, Richter RJ, Marshall JK, Eintracht JF, Rosenthal EA, Furlong CE, Jarvik GP (2012)
Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease
J Lipids 2012: 476316

Kim DS, Burt AA, Ranchalis JE, Richter RJ, Marshall JK, Nakayama KS, Jarvik ER, Eintracht JF, Rosenthal EA, Furlong CE, Jarvik GP (2012)
Dietary cholesterol increases paraoxonase 1 enzyme activity
J Lipid Res 53: 2450

Cole TB, Beyer RP, Bammler TK, Park SS, Farin FM, Costa LG, Furlong CE (2011)
Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression
Toxicol Sci 123: 155

Costa LG, Giordano G, Furlong CE (2011)
Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on
Biochemical Pharmacology 81: 337

Furlong CE (2011)
Exposure to triaryl phosphates: metabolism and biomarkers of exposure
J Biol Phys Chem 11:

Giordano G, Cole TB, Furlong CE, Costa LG (2011)
Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role?
Toxicol Appl Pharmacol 256: 369

Liyasova M, Li B, Schopfer LM, Nachon F, Masson P, Furlong CE, Lockridge O (2011)
Exposure to tri-o-cresyl phosphate detected in jet airplane passengers
Toxicol Appl Pharmacol 256: 337

Marsillach J, Richter RJ, Kim JH, Stevens RC, Maccoss MJ, Tomazela D, Suzuki SM, Schopfer LM, Lockridge O, Furlong CE (2011)
Biomarkers of organophosphorus (OP) exposures in humans
Neurotoxicology 32: 656

Cole TB, Jansen K, Park S, Li WF, Furlong CE, Costa LG (2010)
The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status
Advances in Experimental Medicine & Biology 660: 47

Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP (2010)
Human PON1, a biomarker of risk of disease and exposure
Chemico-Biological Interactions 187: 355

Hofmann JN, Keifer MC, De Roos AJ, Fenske RA, Furlong CE, van Belle G, Checkoway H (2010)
Occupational determinants of serum cholinesterase inhibition among organophosphate-exposed agricultural pesticide handlers in Washington State
Occup Environ Med 67: 375

Kim JH, Stevens RC, Maccoss MJ, Goodlett DR, Scherl A, Richter RJ, Suzuki SM, Furlong CE (2010)
Identification and characterization of biomarkers of organophosphorus exposures in humans
Advances in Experimental Medicine & Biology 660: 61

Mackenzie Ross SJ, Brewin CR, Curran HV, Furlong CE, Abraham-Smith KM, Harrison V (2010)
Neuropsychological and psychiatric functioning in sheep farmers exposed to low levels of organophosphate pesticides
Neurotoxicology & Teratology 32: 452

Richter RJ, Jarvik GP, Furlong CE (2010)
Paraoxonase 1 status as a risk factor for disease or exposure
Advances in Experimental Medicine & Biology 660: 29

Schopfer LM, Furlong CE, Lockridge O (2010)
Development of diagnostics in the search for an explanation of aerotoxic syndrome
Analytical Biochemistry 404: 64

Suzuki SM, Stevens RC, Richter RJ, Cole TB, Park S, Otto TC, Cerasoli DM, Lenz DE, Furlong CE (2010)
Engineering human PON1 in an E. coli expression system
Advances in Experimental Medicine & Biology 660: 37

Ticozzi N, LeClerc AL, Keagle PJ, Glass JD, Wills AM, van Blitterswijk M, Bosco DA, Rodriguez-Leyva I, Gellera C, Ratti A, Taroni F, McKenna-Yasek D, Sapp PC, Silani V, Furlong CE, Brown RH, Jr., Landers JE (2010)
Paraoxonase gene mutations in amyotrophic lateral sclerosis
Annals of Neurology 68: 102

Hofmann JN, Keifer MC, Furlong CE, De Roos AJ, Farin FM, Fenske RA, van Belle G, Checkoway H (2009)
Serum cholinesterase inhibition in relation to paraoxonase-1 (PON1) status among organophosphate-exposed agricultural pesticide handlers
Environmental Health Perspectives 117: 1402

Huen K, Richter R, Furlong CE, Eskenazi B, Holland NT (2009)
Validation of PON1 enzyme activity assays for longitudinal studies
Clinica Chimica Acta 402: 67

Jansen KL, Cole TB, Park SS, Furlong CE, Costa LG (2009)
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds
Toxicol Appl Pharmacol 236: 142

Richter RJ, Jarvik GP, Furlong CE (2009)
Paraoxonase 1 (PON1) status and substrate hydrolysis
Toxicol Appl Pharmacol 235: 1

Richter RJ, Jarvik GP, Furlong CE (2008)
Determination of paraoxonase 1 status without the use of toxic organophosphate substrates
Circ Cardiovasc Genet 1: 147

Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, Furlong CE, Brown RH, Jr. (2008)
Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS
Neurology 70: 929

Furlong CE (2007)
Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds
J Biochem Mol Toxicol 21: 197

Furlong CE, Holland NT, Richter RJ, Bradman A, Ho A, Eskenazi B (2006)
PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity
Pharmacogenet Genomics 16: 183

Holland NT, Furlong CE, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B (2006)
Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns
Environmental Health Perspectives 114: 985

Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE (2005)
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism
Pharmacogenet Genomics 15: 589

Costa LG, Cole TB, Furlong CE (2005)
Paraoxonase (PON1): from toxicology to cardiovascular medicine
Acta Biomed 76 Suppl 2: 50

Costa LG, Cole TB, Vitalone A, Furlong CE (2005)
Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity
Clinica Chimica Acta 352: 37

Costa LG, Vitalone A, Cole TB, Furlong CE (2005)
Modulation of paraoxonase (PON1) activity
Biochemical Pharmacology 69: 541

Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG (2005)
Paraoxonase 1 (PON1) status and risk of insecticide exposure
J Biochem Mol Toxicol 19: 182

Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG (2005)
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants
Neurotoxicology 26: 651

Rozek LS, Hatsukami TS, Richter RJ, Ranchalis J, Nakayama K, McKinstry LA, Gortner DA, Boyko E, Schellenberg GD, Furlong CE, Jarvik GP (2005)
The correlation of paraoxonase (PON1) activity with lipid and lipoprotein levels differs with vascular disease status
J Lipid Res 46: 1888

Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, Holland NT (2005)
Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates
Neurotoxicology 26: 199

Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr DB, Furlong CE, Holland NT (2004)
Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population
Environmental Health Perspectives 112: 1116

Jarvik GP, Jampsa R, Richter RJ, Carlson CS, Rieder MJ, Nickerson DA, Furlong CE (2003)
Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status
Pharmacogenetics 13: 291

Brophy VH, Jarvik GP, Richter RJ, Rozek LS, Schellenberg GD, Furlong CE (2000)
Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype
Pharmacogenetics 10: 453

Furlong CE, Li WF, Richter RJ, Shih DM, Lusis AJ, Alleva E, Costa LG (2000)
Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1)
Neurotoxicology 21: 91

Li WF, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE (2000)
Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds
Pharmacogenetics 10: 767

Costa LG, Li WF, Richter RJ, Shih DM, Lusis A, Furlong CE (1999)
The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism
Chemico-Biological Interactions 119-120: 429

La Du BN, Furlong CE, Reiner E (1999)
Recommended nomenclature system for the paraoxonases
Chemico-Biological Interactions 119-120: 599

Furlong CE, Li WF, Costa LG, Richter RJ, Shih DM, Lusis AJ (1998)
Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism
Neurotoxicology 19: 645

Shih DM, Gu L, Xia YR, Navab M, Li WF, Hama S, Castellani LW, Furlong CE, Costa LG, Fogelman AM, Lusis AJ (1998)
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
Nature 394: 284

Li WF, Matthews C, Disteche CM, Costa LG, Furlong CE (1997)
Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression
Pharmacogenetics 7: 137

Yuknavage KL, Fenske RA, Kalman DA, Keifer MC, Furlong CE (1997)
Simulated dermal contamination with capillary samples and field cholinesterase biomonitoring
J Toxicol Environ Health 51: 35

Clendenning JB, Humbert R, Green ED, Wood C, Traver D, Furlong CE (1996)
Structural organization of the human PON1 gene
Genomics 35: 586

Davies HG, Richter RJ, Keifer M, Broomfield CA, Sowalla J, Furlong CE (1996)
The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
Nat Genet 14: 334

Nevin DN, Zambon A, Furlong CE, Richter RJ, Humbert R, Hokanson JE, Brunzell JD (1996)
Paraoxonase genotypes, lipoprotein lipase activity, and HDL
Arterioscler Thromb Vasc Biol 16: 1243

Li WF, Furlong CE, Costa LG (1995)
Paraoxonase protects against chlorpyrifos toxicity in mice
Toxicology Letters 76: 219

Furlong CE, Costa LG, Hassett C, Richter RJ, Sundstrom JA, Adler DA, Disteche CM, Omiecinski CJ, Chapline C, Crabb JW, et al. (1993)
Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification
Chemico-Biological Interactions 87: 35

Li WF, Costa LG, Furlong CE (1993)
Serum paraoxonase status: a major factor in determining resistance to organophosphates
Journal of Toxicology & Environmental Health 40: 337

Hassett C, Richter RJ, Humbert R, Chapline C, Crabb JW, Omiecinski CJ, Furlong CE (1991)
Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence
Biochemistry 30: 10141

Costa LG, McDonald BE, Murphy SD, Omenn GS, Richter RJ, Motulsky AG, Furlong CE (1990)
Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats
Toxicol Appl Pharmacol 103: 66