Dvir H, Silman I, Harel M, Rosenberry TL, Sussman JL (2010)
Acetylcholinesterase: from 3D structure to function
Chemico-Biological Interactions 187: 10
Dvir H, Jiang H, Wong DM, Harel M, Chetrit M, He XC, Jin GY, Yu GL, Tang XC, Silman I, Bai DL, Sussman JL (2004)
Poster (79) X-ray structures of TcAChE complexed with (+)-huperzine a and (-)-huperzine b: structural evidence for an active-site rearrangement
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 362
Dvir H, Harel M, Bon S, Liu WQ, Vidal M, Garbay C, Sussman JL, Massoulie J, Silman I (2004)
The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix
EMBO Journal 23: 4394
Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS (2004)
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes
Nat Struct Mol Biol 11: 412
Harel M, Dvir H, Bon S, Liu WQ, Garbay C, Sussman JL, Massoulie J, Silman I (2004)
Crystal structure of the tetramerization domain of acetylcholinesterase at 2.
Cholinergic Mechanisms, CRC Press
Harel M, Dvir H, Bon S, Liu WQ, Garbay C, Sussman JL, Massoulie J, Silman I (2004)
Poster (48) Crystal structure of the tetramerization domain of acetylcholinesterase reveals a model of the AChE tetramer
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 347
Greenblatt HM, Dvir H, Silman I, Sussman JL (2003)
Acetylcholinesterase: a multifaceted target for structure-based drug design of anticholinesterase agents for the treatment of Alzheimer's disease
Journal of Molecular Neuroscience 20: 369
Wong DM, Greenblatt HM, Dvir H, Carlier PR, Han YF, Pang YP, Silman I, Sussman JL (2003)
Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity
J Am Chem Soc 125: 363
Bar-On P, Millard CB, Harel M, Dvir H, Enz A, Sussman JL, Silman I (2002)
Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine
Biochemistry 41: 3555
Dvir H, Wong DM, Harel M, Barril X, Orozco M, Luque FJ, Munoz-Torrero D, Camps P, Rosenberry TL, Silman I, Sussman JL (2002)
3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates
Biochemistry 41: 2970
Dvir H, Jiang H, Wong DM, Harel M, Chetrit M, He XC, Jin GY, Yu GL, Tang XC, Silman I, Bai DL, Sussman JL (2002)
X-ray Structures of Torpedo californica Acetylcholinesterase Complexed with (+)-Huperzine A and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement
Biochemistry 41: 10810