Da Silva O, Probst N, Landry C, Hanak AS, Warnault P, Coisne C, Calas AG, Gosselet F, Courageux C, Gastellier AJ, Trancart M, Baati R, Dehouck MP, Jean L, Nachon F, Renard PY, Dias J (2022)
A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning
Journal of Medicinal Chemistry

Femy F, Meesemaecker G, Belverge N, Courageux C, Nervo A, Goulay R, Reymond C, Chantegreil F, Madi M, Nachon F, Taudon N, Jaffre N (2022)
Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method
Archives of Toxicology

Nachon F, Brazzolotto X, Dias J, Courageux C, Drozdz W, Cao XY, Stefankiewicz AR, Lehn JM (2022)
Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions

Gorecki L, Hepnarova V, Karasova JZ, Hrabinova M, Courageux C, Dias J, Kucera T, Kobrlova T, Muckova L, Prchal L, Malinak D, Jun D, Musilek K, Worek F, Nachon F, Soukup O, Korabecny J (2021)
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
Archives of Toxicology

Miles JA, Ng JH, Sreenivas BY, Courageux C, Igert A, Dias J, McGeary RP, Brazzolotto X, Ross BP (2021)
Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database
Chemical Biology Drug Des

Calas AG, Hanak AS, Jaffre N, Nervo A, Dias J, Rousseau C, Courageux C, Brazzolotto X, Villa P, Obrecht A, Goossens JF, Landry C, Hachani J, Gosselet F, Dehouck MP, Yerri J, Kliachyna M, Baati R, Nachon F (2020)
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime
Biomolecules 10:

Miles JA, Kapure JS, Singh Deora G, Courageux C, Igert A, Dias J, McGeary RP, Brazzolotto X, Ross BP (2020)
Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening
Bioorganic & Medicinal Chemistry Lett

Yerri J, Dias J, Nimmakayala MR, Razafindrainibe F, Courageux C, Gastellier AJ, Jegoux J, Coisne C, Landry C, Gosselet F, Hachani J, Goossens JF, Dehouck MP, Nachon F, Baati R (2020)
Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability
Chemistry 26: 15035

Touvrey C, Courageux C, Guillon V, Terreux R, Nachon F, Brazzolotto X (2019)
X-ray structures of human bile-salt activated lipase conjugated to nerve agents surrogates
Toxicology 411: 15