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Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases
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Chen Z, Yu J, Sun K, Song J, Chen L, Jiang Y, Wang Z (2023)
Rational design of a turn-on near-infrared fluorescence probe for the highly sensitive and selective monitoring of carboxylesterase 2 in living systems
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Chen L, Song J, Wang J, Ye M, Deng Q, Wu X, Ren B (2023)
Effects of Methyl Jasmonate Fumigation on the Growth and Detoxification Ability of Spodoptera litura to Xanthotoxin
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Dang H, Chen W, Chen L, Huo X, Wang F (2023)
TPPU inhibits inflammation-induced excessive autophagy to restore the osteogenic differentiation potential of stem cells and improves alveolar ridge preservation
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Jia X, Zhao K, Zhao J, Lin C, Zhang H, Chen L, Chen J, Fang Y (2023)
Degradation of poly(butylene adipate-co-terephthalate) films by Thermobifida fusca FXJ-1 isolated from compost
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Jin P, Chen L, Zhong J, Yuan T, Gan L, Huang J, Wang L, Fan H, Lin C (2023)
Screening and identification of lipase inhibitors extracted from Dioscorea nipponica Makino by UV-vis and HPLC coupled to UPLC-Q-TOF-MS/MS
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Meng R, Ou K, Chen L, Jiao Y, Jiang F, Gu R (2023)
Response Surface Optimization of Extraction Conditions for the Active Components with High Acetylcholinesterase Inhibitory Activity and Identification of Key Metabolites from Acer truncatum Seed Oil Residue
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Pu Y, Chen L, He X, Cao J, Jiang W (2023)
Soluble polysaccharides decrease inhibitory activity of banana condensed tannins against porcine pancreatic lipase
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Xie Y, Liu L, Zheng J, Shi K, Ai W, Zhang X, Wang P, Lan Z, Chen L (2023)
Polygoni Multiflori Radix Praeparata and Acori Tatarinowii Rhizoma ameliorate scopolamine-induced cognitive impairment by regulating the cholinergic and synaptic associated proteins
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Bi XJ, Lv YQ, Yang XH, Ge Y, Han H, Feng JS, Zhang M, Chen L, Xu MZ, Guan FY (2022)
A New Berberine Preparation Protects Pancreatic Islet Cells from Apoptosis Mediated by Inhibition of Phospholipase A(2)/p38 MAPK Pathway
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Chen Z, Yu X, Chen L, Xu L, Cai Y, Hou S, Zheng M, Liu F (2022)
Design, synthesis, and evaluation of 8-aminoquinoline-melatonin derivatives as effective multifunctional agents for Alzheimer's disease
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Chen L, Pi Y, Chang K, Luo S, Peng Z, Chen M, Yu L (2022)
Screening models combining maternal characteristics and multiple markers for the early prediction of preeclampsia in pregnancy: a nested case-control study
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Chen GY, Yin SJ, Chen L, Zhou X, Yang FQ (2022)
Nanoporous ZIF-8 Microparticles as Acetylcholinesterase and Alkaline Phosphatase Mimics for the Selective and Sensitive Detection of Ascorbic Acid Oxidase and Copper Ions
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Du F, Cao R, Chen L, Sun J, Shi Y, Fu Y, Hammock BD, Zheng Z, Liu Z, Chen G (2022)
Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain
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Hu Q, Wang Q, Xu W, Huang C, Tao S, Qi X, Zhang Y, Li X, Jiang X, Song J, Li Q, Chen L, Huang Y (2022)
Development and Validation of a Non-invasive Model to Predict Liver Histological Lesions in Chronic Hepatitis B Patients With Persistently Normal Alanine Aminotransferase and Detectable Viremia
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Liu X, Viswanadhapalli S, Kumar S, Lee TK, Moore A, Ma S, Chen L, Hsieh M, Li M, Sareddy GR, Parra K, Blatt EB, Reese TC, Zhao Y, Chang A, Yan H, Xu Z, Pratap UP, Liu Z, Roggero CM, Tan Z, Weintraub ST, Peng Y, Tekmal RR, Arteaga CL, Lippincott-Schwartz J, Vadlamudi RK, Ahn JM, Raj GV (2022)
Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
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Liu Y, Gan L, Feng P, Huang L, Chen L, Li S, Chen H (2022)
An artificial self-assembling peptide with carboxylesterase activity and substrate specificity restricted to short-chain acid p-nitrophenyl esters
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Ma S, Ding L, Cai M, Chen L, Yan B, Yang J (2022)
Association Lp-PLA2 Gene Polymorphisms with Coronary Heart Disease
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Peng X, Chen L, Wang Z, He Y, Ruganzu JB, Guo H, Zhang X, Ji S, Zheng L, Yang W (2022)
Tanshinone IIA regulates glycogen synthase kinase-3beta-related signaling pathway and ameliorates memory impairment in APP/PS1 transgenic mice
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Shang N, Chen L, Cheng M, Tian Y, Huang X (2022)
Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp. YS-1 and characterization of two initial degrading esterases
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Song Z, Li X, Xu K, Sun G, Yang L, Huang L, Liu J, Yin P, Huang S, Gao F, Zhou X, Chen L (2022)
Design, synthesis and insecticidal activity and mechanism research of Chasmanthinine derivatives
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Sun X, Wang Y, Lei Z, Yue S, Chen L, Sun J (2022)
Development of 5-hydroxyl-1-azabenzanthrone derivatives as dual binding site and selective acetylcholinesterase inhibitors
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Tian Y, Fan Y, Chen L, Sun M (2022)
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Wan T, Au DW, Mo J, Chen L, Cheung KM, Kong RY, Seemann F (2022)
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Wang Y, Chen L, Liu H, Xie J, Yin W, Xu Z, Ma H, Wu W, Zheng M, Liu M, Liu J (2022)
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Wu Y, Chen L, Xie Z, Wang C, Zhang J, Yan X (2022)
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Wu S, Chen L, Zhou Y, Xiao F, Liu D, Wang Y (2022)
Invasive Plants Have Higher Resistance to Native Generalist Herbivores Than Exotic Noninvasive Congeners
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Xiang K, He Z, Fu J, Wang G, Li H, Zhang Y, Zhang S, Chen L (2022)
Microplastics exposure as an emerging threat to ancient lineage: A contaminant of concern for abnormal bending of amphioxus via neurotoxicity
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Xiang L, Wu Q, Sun H, Miao X, Lv Z, Liu H, Chen L, Gu Y, Chen J, Zhou S, Jiang H, Du S, Zhou Y, Dong H, Fan Y, Miao S, Lu Q, Chang L, Wang H, Lu Y, Xu X, Wang W, Huang Z (2022)
SARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice
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Xiao Y, Wu N, Wang L, Chen L (2022)
A Novel Paper-Based Electrochemical Biosensor Based on N,O-Rich Covalent Organic Frameworks for Carbaryl Detection
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Yang W, Sun L, Dong P, Chen Y, Zhang H, Huang X, Wu L, Chen L, Jing D, Wu Y (2022)
Structure-guided rational design of the Geobacillus thermoglucosidasius feruloyl esterase GthFAE to improve its thermostability
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Yang Y, Yu Q, Zhang C, Wang X, He L, Huang Y, Li E, Qin J, Chen L (2022)
Acute thiamethoxam exposure induces hepatotoxicity and neurotoxicity in juvenile Chinese mitten crab (Eriocheir sinensis)
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Yu H, Yang L, Long H, Su X, Wang Y, Xing Q, Yao R, Zhang M, Chen L (2022)
Strigolactone signaling complex formation in yeast: A paradigm for studying hormone-induced receptor interaction with multiple downstream proteins
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Zhou X, Yang HB, Luo YY, Xu JB, Liu Y, Gao F, Huang S, Chen L (2022)
Two new C18-diterpenoid alkaloids from Aconitum leucostomum Worosch
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Zhu X, Chen L, Liu T, He S, Zhao X, Tian Y, Fang Y, Cui J (2022)
Detecting the combined toxicity of 18 binary and 24 ternary pesticide combinations to carboxylesterase based on fluorescence probe technology
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Bi Y, Zhang J, Zeng D, Chen L, Ye W, Yang Q, Ling Y (2021)
Cholinesterase is Associated With Prognosis and Response to Chemotherapy in Advanced Gastric Cancer
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Chen L, Tian X, Li Y, Lu L, Nie Y, Wang Y (2021)
Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array system
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Chen J, Zhang Y, Chai Y, Meng Z, Chen L, Quan D, Wang Y, Meng Q, Li C (2021)
Synergistic enhancement of the emergency treatment effect of organophosphate poisoning by a supramolecular strategy
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He N, Yu L, Xu M, Huang Y, Wang X, Chen L, Yue S (2021)
Near-infrared fluorescent probe for evaluating the acetylcholinesterase effect in the aging process and dietary restriction via fluorescence imaging
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Hu A, Zhao Q, Chen L, Zhao J, Wang Y, Feng K, Wu L, Xie M, Zhou X, Xiao L, Ming Z, Zhang M, Yao R (2021)
Identification of Conserved and Divergent Strigolactone Receptors in Sugarcane Reveals a Key Residue Crucial for Plant Branching Control
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Li S, Li Y, Chen L, Zhang C, Wang F, Li H, Wang M, Wang Y, Nan F, Xie D, Yan J (2021)
Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development
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Li X, Ye M, Gao F, Zhou X, Chen L, Huang S (2021)
A new diterpenoid alkaloid from Delphinium gyalanum C. Marquand & Airy Shaw
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Li L, Li J, Dai Y, Yang M, Liang S, Wang Z, Liu W, Chen L, Tao J (2021)
Electro-Acupuncture Improve the Early Pattern Separation in Alzheimer's Disease Mice via Basal Forebrain-Hippocampus Cholinergic Neural Circuit
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Wang Y, Yao R, Du X, Guo L, Chen L, Xie D, Smith SM (2021)
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Wong JC, Grieco SF, Dutt K, Chen L, Thelin JT, Inglis GAS, Parvin S, Garraway SM, Xu X, Goldin AL, Escayg A (2021)
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Zhu H, Cong L, Chen Y, Chen S, Chen L, Huang Z, Zhou J, Xiao J, Huang Y, Su D (2021)
Efficiency of donepezil in elderly patients undergoing orthopaedic surgery due to underlying post-operative cognitive dysfunction: study protocol for a multicentre randomised controlled trial
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Fellner M, Lentz CS, Jamieson SA, Brewster JL, Chen L, Bogyo M, Mace PD (2020)
Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus
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Huang J, Zhao Q, Chen L, Zhang C, Bu W, Zhang X, Zhang K, Yang Z (2020)
Improved production of recombinant Rhizomucor miehei lipase by coexpressing protein folding chaperones in Pichia pastoris, which triggered ER stress
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Huang S, Zhang JF, Chen L, Gao F, Zhou XL (2020)
Diterpenoid alkaloids from Aconitum anthoroideum that offer protection against MPP(+)-Induced apoptosis of SH-SY5Y cells and acetylcholinesterase inhibitory activity
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Huang Z, Cao Z, Guo Z, Chen L, Wang Z, Sui X, Jiang L (2020)
Lipase catalysis of alpha-linolenic acid-rich medium- and long-chain triacylglycerols from perilla oil and medium-chain triacylglycerols with reduced by-products
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Huang Z, Guo Z, Xie D, Cao Z, Chen L, Wang H, Jiang L, Shen Q (2020)
Rhizomucor miehei lipase-catalysed synthesis of cocoa butter equivalent from palm mid-fraction and stearic acid: Characteristics and feasibility as cocoa butter alternative
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Jiang X, Zhou J, Wang Y, Chen L, Duan Y, Huang J, Liu C, Chen Y, Liu W, Sun H, Feng F, Qu W (2020)
Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease
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Jing M, Li Y, Zeng J, Huang P, Skirzewski M, Kljakic O, Peng W, Qian T, Tan K, Zou J, Trinh S, Wu R, Zhang S, Pan S, Hires SA, Xu M, Li H, Saksida LM, Prado VF, Bussey TJ, Prado MAM, Chen L, Cheng H (2020)
An optimized acetylcholine sensor for monitoring in vivo cholinergic activity
Nat Methods 17: 1139

Liu M, Song S, Hu C, Tang L, Lam JCW, Lam PKS, Chen L (2020)
Dietary administration of probiotic Lactobacillus rhamnosus modulates the neurological toxicities of perfluorobutanesulfonate in zebrafish
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Liu S, Dang M, Lei Y, Ahmad SS, Khalid M, Kamal MA, Chen L (2020)
Ajmalicine and its Analogues against AChE and BuChE for the Management of Alzheimer's Disease: An In-silico study
Curr Pharm Des

Ren J, Jiang F, Wang M, Hu H, Zhang B, Chen L, Dai F (2020)
Increased cross-linking micelle retention in the brain of Alzheimer's disease mice by elevated asparagine endopeptidase protease responsive aggregation
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Shi Q, Guo W, Shen Q, Han J, Lei L, Chen L, Yang L, Feng C, Zhou B (2020)
In vitro biolayer interferometry analysis of acetylcholinesterase as a potential target of aryl-organophosphorus flame-retardants
J Hazard Mater 409: 124999

Wang WG, Wang H, Du LQ, Li M, Chen L, Yu J, Cheng GG, Zhan MT, Hu QF, Zhang L, Yao M, Matsuda Y (2020)
Molecular Basis for the Biosynthesis of an Unusual Chain-Fused Polyketide Gregatin A
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Wei X, Chen L, Tang JW, Matsuda Y (2020)
Discovery of Pyranoviolin A and Its Biosynthetic Gene Cluster in Aspergillus violaceofuscus
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Zhang J, Fu B, Lin Q, Riley IT, Ding S, Chen L, Cui J, Yang L, Li H (2020)
Colonization of Beauveria bassiana 08F04 in root-zone soil and its biocontrol of cereal cyst nematode (Heterodera filipjevi)
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Chen L, Zhang J, Suo H, Wang W, Wang H, Zhang Y, Hu Q, Zhao X, Li J (2019)
Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice
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Chen L, Keller LJ, Cordasco E, Bogyo M, Lentz CS (2019)
Fluorescent Triazole Urea Activity-Based Probes for the Single-Cell Phenotypic Characterization of Staphylococcus aureus
Angew Chem Int Ed Engl 58: 5643

Guo E, Hu Y, Du T, Zhu H, Chen L, Qu W, Zhang J, Xie N, Liu W, Feng F, Xu J (2019)
Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo
Bioorg Chem 92: 103258

Han Y, Ye Z, Wang F, Chen T, Wei L, Chen L, Xiao L (2019)
Single-particle enumeration-based ultrasensitive enzyme activity quantification with fluorescent polymer nanoparticles
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He D, Yue Z, Liu L, Fang X, Chen L, Han H (2019)
Long noncoding RNA ABHD11-AS1 promote cells proliferation and invasion of colorectal cancer via regulating the miR-1254-WNT11 pathway
Journal of Cellular Physiology 234: 12070

Huang J, Wang Q, Bu W, Chen L, Yang Z, Zheng W, Li Y, Li J (2019)
Different construction strategies affected on the physiology of Pichia pastoris strains highly expressed lipase by transcriptional analysis of key genes
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Ling L, Liu Y, Sun Y, Cai Y, Jiang Y, Chen L, He L, Xue J (2019)
Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining
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Shi Q, Tsui MMP, Hu C, Lam JCW, Zhou B, Chen L (2019)
Acute exposure to triphenyl phosphate (TPhP) disturbs ocular development and muscular organization in zebrafish larvae
Ecotoxicology & Environmental Safety 179: 119

Xu H, Chen L, Zhang X, Jiang X, Tian W, Yu W, Wang X, Tian J, Su D (2019)
Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction
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Yin Z, Zhang J, Guo Q, Chen L, Zhang W, Kang W (2019)
Pharmacological Effects of Verticine: Current Status
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Zhang L, Chen L, Meng Z, Zhang W, Xu X, Wang Z, Qin Y, Deng Y, Liu R, Zhou Z, Diao J (2019)
Bioaccumulation, behavior changes and physiological disruptions with gender-dependent in lizards (Eremias argus) after exposure to glufosinate-ammonium and l-glufosinate-ammonium
Chemosphere 226: 817

Zhao Z, Zhang Y, Gong A, Liu N, Chen S, Zhao X, Li X, Chen L, Zhou C, Wang J (2019)
Biodegradation of mycotoxin fumonisin B1 by a novel bacterial consortium SAAS79
Applied Microbiology & Biotechnology 103: 7129

Zheng S, Zhu R, Zhou X, Chen L, Bai H, Zhang J (2019)
Synthesis and biological evaluation of calycanthaceous alkaloid analogs
Bioorganic & Medicinal Chemistry

Kuhnert E, Li Y, Lan N, Yue Q, Chen L, Cox RJ, An Z, Yokoyama K, Bills GF (2018)
Enfumafungin synthase represents a novel lineage of fungal triterpene cyclases
Environ Microbiol 20: 3325

Tang M, Lu L, Huang Z, Chen L (2018)
Palmitoylation signaling: a novel mechanism of mitochondria dynamics and diverse pathologies
Acta Biochim Biophys Sin (Shanghai) 50: 831

Wan L, Lu J, Fu J, Huang J, Yang Q, Xin B, Chen L, Huo Y, Zhong Y, Guo C (2018)
Acetylcholinesterase Inhibitor Donepezil Effects on Plasma beta-Hydroxybutyrate Levels in the Treatment of Alzheimer's Disease
Curr Alzheimer Res 15: 917

Wingfield BD, Bills GF, Dong Y, Huang W, Nel WJ, Swalarsk-Parry BS, Vaghefi N, Wilken PM, An Z, de Beer ZW, De Vos L, Chen L, Duong TA, Gao Y, Hammerbacher A, Kikkert JR, Li Y, Li H, Li K, Li Q, Liu X, Ma X, Naidoo K, Pethybridge SJ, Sun J, Steenkamp ET, van der Nest MA, van Wyk S, Wingfield MJ, Xiong C, Yue Q, Zhang X (2018)
IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium, Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis basicola), Ceratocystis smalleyi, two Cercospora beticola strains, Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina, and Morchella septimelata
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Wu W, Liang X, Xie G, Chen L, Liu W, Luo G, Zhang P, Yu L, Zheng X, Ji H, Zhang C, Yi W (2018)
Synthesis and Evaluation of Novel Ligustrazine Derivatives as Multi-Targeted Inhibitors for the Treatment of Alzheimer's Disease
Molecules 23:

Yao R, Chen L, Xie D (2018)
Irreversible strigolactone recognition: a non-canonical mechanism for hormone perception
Curr Opin Plant Biol 45: 155

Yao R, Wang L, Li Y, Chen L, Li S, Du X, Wang B, Yan J, Li J, Xie D (2018)
Rice DWARF14 acts as an unconventional hormone receptor for strigolactone
J Exp Bot 69: 2355

Zhang J, Lu L, Chen F, Chen L, Yin J, Huang X (2018)
Detoxification of diphenyl ether herbicide lactofen by Bacillus sp. Za and enantioselective characteristics of an esterase gene lacE
J Hazard Mater 341: 336

Zhang J, Chen L, Sun J (2018)
Oxoisoaporphine Alkaloids: Prospective Anti-Alzheimer's Disease, Anticancer, and Antidepressant Agents
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Zhang M, Li H, Chen L, Fang S, Xie S, Lin C (2018)
Three-dimensional reconstructed eccrine sweat glands with vascularization and cholinergic and adrenergic innervation
J Mol Histol 49: 339

Di S, Liu R, Tian Z, Cheng C, Chen L, Zhang W, Zhou Z, Diao J (2017)
Assessment of tissue-specific accumulation, elimination and toxic effects of dichlorodiphenyltrichloroethanes (DDTs) in carp through aquatic food web
Sci Rep 7: 2288

Guo L, Li Z, Chen H, Wu Y, Chen L, Song Z, Lin T (2017)
Colorimetric biosensor for the assay of paraoxon in environmental water samples based on the iodine-starch color reaction
Anal Chim Acta 967: 59

Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X (2017)
Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase
Biochimica & Biophysica Acta 1863: 1382

Liu Z, Fang L, Zhang H, Gou S, Chen L (2017)
Design, synthesis and biological evaluation of multifunctional tacrine-curcumin hybrids as new cholinesterase inhibitors with metal ions-chelating and neuroprotective property
Bioorganic & Medicinal Chemistry 25: 2387

Luo D, Chen L, Yu B (2017)
Inhibition of the high affinity choline transporter enhances hyperalgesia in a rat model of chronic pancreatitis
Biochemical & Biophysical Research Communications 488: 204

Sokolow S, Li X, Chen L, Taylor KD, Rotter JI, Rissman RA, Aisen PS, Apostolova LG (2017)
Deleterious Effect of Butyrylcholinesterase K-Variant in Donepezil Treatment of Mild Cognitive Impairment
J Alzheimers Dis 56: 229

Su J, Liu H, Guo K, Chen L, Yang M, Chen Q (2017)
Research Advances and Detection Methodologies for Microbe-Derived Acetylcholinesterase Inhibitors: A Systemic Review
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Sun W, Chen L, Zheng W, Wei X, Wu W, Duysen EG, Jiang W (2017)
Study of acetylcholinesterase activity and apoptosis in SH-SY5Y cells and mice exposed to ethanol
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Xiang CP, Han JX, Li XC, Li YH, Zhang Y, Chen L, Qu Y, Hao CY, Li HZ, Yang CR, Zhao SJ, Xu M (2017)
Chemical Composition and Acetylcholinesterase Inhibitory Activity of Essential Oils from Piper Species
Journal of Agricultural and Food Chemistry 65: 3702

Yao R, Wang F, Ming Z, Du X, Chen L, Wang Y, Zhang W, Deng H, Xie D (2017)
ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds
Cell Res 27: 838

Chen L, Lu W, Fang L, Xiong H, Wu X, Zhang M, Wu S, Yu D (2016)
Association between L55M polymorphism in Paraoxonase 1 and cancer risk: a meta-analysis based on 21 studies
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Chen L, Li Y, Yue Q, Loksztejn A, Yokoyama K, Felix EA, Liu X, Zhang N, An Z, Bills GF (2016)
Engineering of New Pneumocandin Side-Chain Analogues from Glarea lozoyensis by Mutasynthesis and Evaluation of Their Antifungal Activity
ACS Chemical Biology 11: 2724

Ding J, Li B, Chen L, Qin W (2016)
A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing
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Fang L, Chen M, Liu Z, Fang X, Gou S, Chen L (2016)
Ferulic acid-carbazole hybrid compounds: Combination of cholinesterase inhibition, antioxidant and neuroprotection as multifunctional anti-Alzheimer agents
Bioorganic & Medicinal Chemistry 24: 886

Fang M, Wei JL, Tang B, Liu J, Chen L, Tang ZH, Luo J, Chen GJ, Wang XF (2016)
Neuroligin-1 Knockdown Suppresses Seizure Activity by Regulating Neuronal Hyperexcitability
Molecular Neurobiology 53: 270

Gao W, Wu K, Chen L, Fan H, Zhao Z, Gao B, Wang H, Wei D (2016)
A novel esterase from a marine mud metagenomic library for biocatalytic synthesis of short-chain flavor esters
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Jiang F, Wang X, Wang B, Chen L, Zhao Z, Waterfield NR, Yang G, Jin Q (2016)
The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress
Cell Rep 16: 1502

Yao R, Ming Z, Yan L, Li S, Wang F, Ma S, Yu C, Yang M, Chen L, Li Y, Yan C, Miao D, Sun Z, Yan J, Sun Y, Wang L, Chu J, Fan S, He W, Deng H, Nan F, Li J, Rao Z, Lou Z, Xie D (2016)
DWARF14 is a non-canonical hormone receptor for strigolactone
Nature 536: 469

Yin K, Lv M, Wang Q, Wu Y, Liao C, Zhang W, Chen L (2016)
Simultaneous bioremediation and biodetection of mercury ion through surface display of carboxylesterase E2 from Pseudomonas aeruginosa PA1
Water Res 103: 383

Zha X, Lamba D, Zhang L, Lou Y, Xu C, Kang D, Chen L, Xu Y, De Simone A, Samez S, Pesaresi A, Stojan J, Lopez MG, Egea J, Andrisano V, Bartolini M (2016)
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography
Journal of Medicinal Chemistry 59: 114

Cao J, Dang G, Li H, Li T, Yue Z, Li N, Liu Y, Liu S, Chen L (2015)
Identification and Characterization of Lipase Activity and Immunogenicity of LipL from Mycobacterium tuberculosis
PLoS ONE 10: e0138151

Chen L, Xu W, Shao R, Du X (2015)
Bioactivities of phytochemicals in Araiostegia yunnanensis (Christ)
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Chen QF, Xu L, Tan WJ, Chen L, Qi H, Xie LJ, Chen MX, Liu BY, Yu LJ, Yao N, Zhang JH, Shu W, Xiao S (2015)
Disruption of the Arabidopsis Defense Regulator Genes SAG101, EDS1, and PAD4 Confers Enhanced Freezing Tolerance
Mol Plant 8: 1536

Chen L, Yue Q, Li Y, Niu X, Xiang M, Wang W, Bills GF, Liu X, An Z (2015)
Engineering of Glarea lozoyensis for exclusive production of the pneumocandin B0 precursor of the antifungal drug caspofungin acetate
Applied Environmental Microbiology 81: 1550

Cheng S, Zheng W, Gong P, Zhou Q, Xie Q, Yu L, Zhang P, Chen L, Li J, Chen J, Chen H (2015)
(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-beta aggregation with high antioxidant potency for Alzheimer's therapy
Bioorganic & Medicinal Chemistry 23: 3110

Dang G, Chen L, Li Z, Deng X, Cui Y, Cao J, Yu S, Pang H, Liu S (2015)
Expression, Purification and Characterisation of Secreted Esterase Rv2525c from Mycobacterium tuberculosis
Appl Biochem Biotechnol 176: 1

Li X, Fan D, Zhang W, Liu G, Zhang L, Zhao L, Fang X, Chen L, Dong Y, Chen Y, Ding Y, Zhao R, Feng M, Zhu Y, Feng Y, Jiang X, Zhu D, Xiang H, Feng X, Li S, Wang J, Zhang G, Kronforst MR, Wang W (2015)
Outbred genome sequencing and CRISPR/Cas9 gene editing in butterflies
Nat Commun 6: 8212

Li Y, Chen L, Yue Q, Liu X, An Z, Bills GF (2015)
Genetic Manipulation of the Pneumocandin Biosynthetic Pathway for Generation of Analogues and Evaluation of Their Antifungal Activity
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Liang J, Xu W, Hsu YT, Yee AX, Chen L, Sudhof TC (2015)
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Chen L, Yue Q, Zhang X, Xiang M, Wang C, Li S, Che Y, Ortiz-Lopez FJ, Bills GF, Liu X, An Z (2013)
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Shi Y, Pan Y, Li B, He W, She Q, Chen L (2013)
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Zhang DQ, Chen L, Gan QR, Lin QF, Pan C (2013)
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Zhu X, Ye L, Ge H, Chen L, Jiang N, Qian L, Li L, Liu R, Ji S, Zhang S, Jin J, Guan D, Fang W, Tan R, Xu Y (2013)
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Cejkova D, Zobanikova M, Chen L, Pospisilova P, Strouhal M, Qin X, Mikalova L, Norris SJ, Muzny DM, Gibbs RA, Fulton LL, Sodergren E, Weinstock GM, Smajs D (2012)
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Chen L, Yu K, Huang C, Yu L, Zhu B, Lam PK, Lam JC, Zhou B (2012)
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Chen L, Jiang J, Xu J, Gu Y, Xu L (2012)
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Shi M, Zhang Z, Xu R, Lin H, Fu J, Zou Z, Zhang A, Shi J, Chen L, Lv S, He W, Geng H, Jin L, Liu Z, Wang FS (2012)
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Bolen AL, Naren AP, Yarlagadda S, Beranova-Giorgianni S, Chen L, Norman D, Baker DL, Rowland MM, Best MD, Sano T, Tsukahara T, Liliom K, Igarashi Y, Tigyi G (2011)
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Chen L, Kong X, Liang Z, Ye F, Yu K, Dai W, Wu D, Luo C, Jiang H (2011)
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Yue M, Yang F, Yang J, Bei W, Cai X, Chen L, Dong J, Zhou R, Jin M, Jin Q, Chen H (2009)
Complete genome sequence of Haemophilus parasuis SH0165
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Chen L, Wang X, Lu T, Hou T (2007)
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Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates
Journal of Neuroscience 26: 4681

Wu X, Wang J, Fan J, Chen M, Chen L, Huang W, Liu G (2006)
Localized vessel expression of lipoprotein lipase in rabbits leads to rapid lipid deposition in the balloon-injured arterial wall
Atherosclerosis 187: 65

Chen L, Brugger K, Skovgaard M, Redder P, She Q, Torarinsson E, Greve B, Awayez M, Zibat A, Klenk HP, Garrett RA (2005)
The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota
Journal of Bacteriology 187: 4992

Liang HY, Chen DF, Zhang T, Yang F, Wang LL, Chen L, Wu BY (2005)
[Associations of genetic polymorphisms in the EPHX1 gene and the GSTT1 gene with low birth weight in neonates]
Beijing Da Xue Xue Bao 37: 85

Nam CI, Chen L (2005)
Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter
Proc Natl Acad Sci U S A 102: 6137

Park JY, Chen L, Wadhwa N, Tockman MS (2005)
Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD
Int J Mol Med 15: 443

Yang F, Yang J, Zhang X, Chen L, Jiang Y, Yan Y, Tang X, Wang J, Xiong Z, Dong J, Xue Y, Zhu Y, Xu X, Sun L, Chen S, Nie H, Peng J, Xu J, Wang Y, Yuan Z, Wen Y, Yao Z, Shen Y, Qiang B, Hou Y, Yu J, Jin Q (2005)
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery
Nucleic Acids Research 33: 6445

Dong H, Xiang YY, Farchi N, Ju W, Wu Y, Chen L, Wang Y, Hochner B, Yang B, Soreq H, Lu WY (2004)
Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons
Journal of Neuroscience 24: 8950

Melo EP, Chen L, Cabral JM, Fojan P, Petersen SB, Otzen DE (2003)
Trehalose favors a cutinase compact intermediate off-folding pathway
Biochemistry 42: 7611

Feng Q, Zhang Y, Hao P, Wang S, Fu G, Huang Y, Li Y, Zhu J, Liu Y, Hu X, Jia P, Zhao Q, Ying K, Yu S, Tang Y, Weng Q, Zhang L, Lu Y, Mu J, Zhang LS, Yu Z, Fan D, Liu X, Lu T, Li C, Wu Y, Sun T, Lei H, Li T, Hu H, Guan J, Wu M, Zhang R, Zhou B, Chen Z, Chen L, Jin Z, Wang R, Yin H, Cai Z, Ren S, Lv G, Gu W, Zhu G, Tu Y, Jia J, Chen J, Kang H, Chen X, Shao C, Sun Y, Hu Q, Zhang X, Zhang W, Wang L, Ding C, Sheng H, Gu J, Chen S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J, Hong G, Xue Y, Han B (2002)
Sequence and analysis of rice chromosome 4
Nature 420: 316

Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD (2002)
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome
Science 296: 1661

Pantoja M, Chen L, Chen Y, Nester EW (2002)
Agrobacterium type IV secretion is a two-step process in which export substrates associate with the virulence protein VirJ in the periplasm
Molecular Microbiology 45: 1325

Holden AJ, Chen L, Shaw IC (2001)
Thermal stability of organophosphorus pesticide triazophos and its relevance in the assessment of risk to the consumer of triazophos residues in food
Journal of Agricultural and Food Chemistry 49: 103

Mulchandani P, Chen W, Mulchandani A, Wang J, Chen L (2001)
Amperometric microbial biosensor for direct determination of organophosphate pesticides using recombinant microorganism with surface expressed organophosphorus hydrolase
Biosensors & Bioelectronics 16: 433

Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigo R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X (2001)
The sequence of the human genome
Science 291: 1304

Wood DW, Setubal JC, Kaul R, Monks DE, Kitajima JP, Okura VK, Zhou Y, Chen L, Wood GE, Almeida NF, Jr., Woo L, Chen Y, Paulsen IT, Eisen JA, Karp PD, Bovee D, Sr., Chapman P, Clendenning J, Deatherage G, Gillet W, Grant C, Kutyavin T, Levy R, Li MJ, McClelland E, Palmieri A, Raymond C, Rouse G, Saenphimmachak C, Wu Z, Romero P, Gordon D, Zhang S, Yoo H, Tao Y, Biddle P, Jung M, Krespan W, Perry M, Gordon-Kamm B, Liao L, Kim S, Hendrick C, Zhao ZY, Dolan M, Chumley F, Tingey SV, Tomb JF, Gordon MP, Olson MV, Nester EW (2001)
The genome of the natural genetic engineer Agrobacterium tumefaciens C58
Science 294: 2317

Yin D, Jin H, Yu H, Chen L (2001)
[A comparative study on the sensitivity and specificity of cholinesterase and glutathione s-transferase in Gammarus pulex L.]
Ying Yong Sheng Tai Xue Bao 12: 615

Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y, Wenthold RJ, Bredt DS, Nicoll RA (2000)
Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms
Nature 408: 936

Myers EW, Sutton GG, Delcher AL, Dew IM, Fasulo DP, Flanigan MJ, Kravitz SA, Mobarry CM, Reinert KH, Remington KA, Anson EL, Bolanos RA, Chou HH, Jordan CM, Halpern AL, Lonardi S, Beasley EM, Brandon RC, Chen L, Dunn PJ, Lai Z, Liang Y, Nusskern DR, Zhan M, Zhang Q, Zheng X, Rubin GM, Adams MD, Venter JC (2000)
A whole-genome assembly of Drosophila
Science 287: 2196

Schutz B, Chen L, Schafer MK, Weihe E, Eiden LE (2000)
Somatomotor neuron-specific expression of the human cholinergic gene locus in transgenic mice
Neuroscience 96: 707

Weihe E, Schafer MK, Schutz B, Anlauf M, Depboylu C, Brett C, Chen L, Eiden LE (1998)
From the cholinergic gene locus to the cholinergic neuron
Journal de Physiologie (Paris) 92: 385

Hahm SH, Chen L, Patel C, Erickson J, Bonner TI, Weihe E, Schafer MK, Eiden LE (1997)
Upstream sequencing and functional characterization of the human cholinergic gene locus
Journal of Molecular Neuroscience 9: 223

Chen L, Patsch W, Boerwinkle E (1996)
HindIII DNA polymorphism in the lipoprotein lipase gene and plasma lipid phenotypes and carotid artery atherosclerosis
Hum Genet 98: 551

Lai X, Liu Y, Chen L (1996)
The effect of indirect injury to peripheral nerves on wound healing after firearm wounds
Journal of Trauma 40: S56