Distaso M, Cea-Rama I, Coscolin C, Chernikova TN, Tran H, Ferrer M, Sanz-Aparicio J, Golyshin PN (2023) <br />The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome<br /><i>Applied Environmental Microbiology</i> <br /><br />Fernandez-Lopez L, Cea-Rama I, Alvarez-Malmagro J, Ressmann AK, Gonzalez-Alfonso JL, Coscolin C, Shahgaldian P, Plou FJ, Modregger J, Pita M, Sanz-Aparicio J, Ferrer M (2023) <br />Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor<br /><i>Chem Commun (Camb)</i> <br /><br />Cea-Rama I, Coscolin C, Gonzalez-Alfonso JL, Raj J, Vasiljevic M, Plou FJ, Ferrer M, Sanz-Aparicio J (2022) <br />Crystal structure of a family VIII beta-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope<br /><i>Febs J</i> <br /><br />Cea-Rama I, Coscolin C, Katsonis P, Bargiela R, Golyshin PN, Lichtarge O, Ferrer M, Sanz-Aparicio J (2021) <br />Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase<br /><i>Comput Struct Biotechnol J</i> <b>19</b>: 2307<br /><br />Alonso S, Santiago G, Cea-Rama I, Fernandez-Lopez L, Coscolin C, Modregger J, Ressmann A, Martinez-Martinez M, Marrero H, Bargiela R, Pita M, Gonzalez-Alfonso JL, Briand M, Rojo D, Barbas C, Plou FJ, Golyshin PN, Shahgaldian P, Sanz-Aparicio J, Guallar V, Ferrer M (2019) <br />Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis<br /><i>Nature Catalysis</i> <b>3</b>: 319<br /><br />Giunta CI, Cea-Rama I, Alonso S, Briand ML, Bargiela R, Coscolin C, Corvini PF, Ferrer M, Sanz-Aparicio J, Shahgaldian P (2020) <br />Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment<br /><i>ACS Nano</i> <br /><br />