Tonelli M, Catto M, Sabate R, Francesconi V, Laurini E, Pricl S, Pisani L, Miniero DV, Liuzzi GM, Gatta E, Relini A, Gavin R, Del Rio JA, Sparatore F, Carotti A (2023)
Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease
Eur Journal of Medicinal Chemistry 250: 115169

Stefanachi A, Leonetti F, Pisani L, Catto M, Carotti A (2018)
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds
Molecules 23:

Park B, Nam JH, Kim JH, Kim HJ, Onnis V, Balboni G, Lee KT, Park JH, Catto M, Carotti A, Lee JY (2017)
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes
Bioorganic & Medicinal Chemistry Lett 27: 1179

Pisani L, Farina R, Soto-Otero R, Denora N, Mangiatordi GF, Nicolotti O, Mendez-Alvarez E, Altomare CD, Catto M, Carotti A (2016)
Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif
Molecules 21:

Pisani L, Farina R, Catto M, Iacobazzi RM, Nicolotti O, Cellamare S, Mangiatordi GF, Denora N, Soto-Otero R, Siragusa L, Altomare CD, Carotti A (2016)
Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents
Journal of Medicinal Chemistry 59: 6791

Farina R, Pisani L, Catto M, Nicolotti O, Gadaleta D, Denora N, Soto-Otero R, Mendez-Alvarez E, Passos CS, Muncipinto G, Altomare CD, Nurisso A, Carrupt PA, Carotti A (2015)
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases
Journal of Medicinal Chemistry 58: 5561

Pau A, Catto M, Pinna G, Frau S, Murineddu G, Asproni B, Curzu MM, Pisani L, Leonetti F, Loza MI, Brea J, Pinna GA, Carotti A (2015)
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors
ChemMedChem 10: 1054

Tonelli M, Catto M, Tasso B, Novelli F, Canu C, Iusco G, Pisani L, Stradis AD, Denora N, Sparatore A, Boido V, Carotti A, Sparatore F (2015)
Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and beta-Amyloid (Abeta) Aggregation
ChemMedChem 10: 1040

Catto M, Pisani L, Leonetti F, Nicolotti O, Pesce P, Stefanachi A, Cellamare S, Carotti A (2013)
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase
Bioorganic & Medicinal Chemistry 21: 146

Catto M, Berezin AA, Lo Re D, Loizou G, Demetriades M, De Stradis A, Campagna F, Koutentis PA, Carotti A (2012)
Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase
Eur Journal of Medicinal Chemistry 58C: 84

Conejo-Garcia A, Pisani L, Nunez Mdel C, Catto M, Nicolotti O, Leonetti F, Campos JM, Gallo MA, Espinosa A, Carotti A (2011)
Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity
Journal of Medicinal Chemistry 54: 2627

Pisani L, Catto M, Leonetti F, Nicolotti O, Stefanachi A, Campagna F, Carotti A (2011)
Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases
Curr Med Chem 18: 4568

Tasso B, Catto M, Nicolotti O, Novelli F, Tonelli M, Giangreco I, Pisani L, Sparatore A, Boido V, Carotti A, Sparatore F (2011)
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease
Eur Journal of Medicinal Chemistry 46: 2170

Pisani L, Catto M, Giangreco I, Leonetti F, Nicolotti O, Stefanachi A, Cellamare S, Carotti A (2010)
Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors
ChemMedChem 5: 1616

Leonetti F, Catto M, Nicolotti O, Pisani L, Cappa A, Stefanachi A, Carotti A (2008)
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors
Bioorganic & Medicinal Chemistry 16: 7450

Carotti A, de Candia M, Catto M, Borisova TN, Varlamov AV, Mendez-Alvarez E, Soto-Otero R, Voskressensky LG, Altomare CD (2006)
Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors
Bioorganic & Medicinal Chemistry 14: 7205

Bruhlmann C, Ooms F, Carrupt PA, Testa B, Catto M, Leonetti F, Altomare CD, Carotti A (2001)
Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase
Journal of Medicinal Chemistry 44: 3195