Mortensen UH, Stennicke HR, Breddam K (1998)
Reversed-flow affinity elution applied to the purification of carboxypeptidase Y
Analytical Biochemistry 258: 236

Olesen K, Breddam K (1997)
Substrates with charged P1 residues are efficiently hydrolyzed by serine carboxypeptidases when S3-P1 interactions are facilitated
Biochemistry 36: 12235

Sorensen SB, Breddam K (1997)
The specificity of carboxypeptidase Y may be altered by changing the hydrophobicity of the S'1 binding pocket
Protein Science 6: 2227

Stennicke HR, Olesen K, Sorensen SB, Breddam K (1997)
C-terminal incorporation of fluorogenic and affinity labels using wild-type and mutagenized carboxypeptidase Y
Analytical Biochemistry 248: 141

Bullock TL, Breddam K, Remington SJ (1996)
Peptide aldehyde complexes with wheat serine carboxypeptidase II: implications for the catalytic mechanism and substrate specificity
Journal of Molecular Biology 255: 714

Stennicke HR, Mortensen UH, Breddam K (1996)
Studies on the hydrolytic properties of (serine) carboxypeptidase Y
Biochemistry 35: 7131

Olesen K, Breddam K (1995)
Increase of the P1 Lys/Leu substrate preference of carboxypeptidase Y by rational design based on known primary and tertiary structures of serine carboxypeptidases
Biochemistry 34: 15689

Sorensen SB, Raaschou-Nielsen M, Mortensen UH, Remington SJ, Breddam K (1995)
Site-Directed Mutagenesis on (Serine) Carboxypeptidase Y from Yeast. The Significance of Thr60 and Met398 in Hydrolysis and Aminolysis Reactions
Journal of the American Chemical Society 117: 5944

Endrizzi JA, Breddam K, Remington SJ (1994)
2.8-A structure of yeast serine carboxypeptidase
Biochemistry 33: 11106

Mortensen UH, Breddam K (1994)
A conserved glutamic acid bridge in serine carboxypeptidases, belonging to the alpha/beta hydrolase fold, acts as a pH-dependent protein-stabilizing element
Protein Science 3: 838

Mortensen UH, Raaschou-Nielsen M, Breddam K (1994)
Recognition of C-terminal amide groups by (serine) carboxypeptidase Y investigated by site-directed mutagenesis
Journal of Biological Chemistry 269: 15528

Mortensen UH, Remington SJ, Breddam K (1994)
Site-directed mutagenesis on (serine) carboxypeptidase Y. A hydrogen bond network stabilizes the transition state by interaction with the C-terminal carboxylate group of the substrate
Biochemistry 33: 508

Olesen K, Mortensen UH, Aasmul-Olsen S, Kielland-Brandt MC, Remington SJ, Breddam K (1994)
The activity of carboxypeptidase Y toward substrates with basic P1 amino acid residues is drastically increased by mutational replacement of leucine 178
Biochemistry 33: 11121

Raaschou-Nielsen M, Mortensen UH, Olesen K, Breddam K (1994)
Improvement of the applicability of carboxypeptidase Y in peptide synthesis by protein engineering
Pept Res 7: 132

Stennicke HR, Mortensen UH, Christensen U, Remington SJ, Breddam K (1994)
Effects of introduced aspartic and glutamic acid residues on the P'1 substrate specificity, pH dependence and stability of carboxypeptidase Y
Protein Engineering 7: 911

Kanstrup A, Breddam K, Buchardt O (1993)
Application of quantitative structure-activity relationship modeling to the evaluation of the changes in enzymatic activity of carboxypeptidase Y upon chemical modifications
Archives of Biochemistry & Biophysics 304: 332

Svendsen I, Hofmann T, Endrizzi J, Remington SJ, Breddam K (1993)
The primary structure of carboxypeptidase S1 from Penicillium janthinellum
FEBS Letters 333: 39

Dal Degan F, Ribadeau-Dumas B, Breddam K (1992)
Purification and characterization of two serine carboxypeptidases from Aspergillus niger and their use in C-terminal sequencing of proteins and peptide synthesis
Applied Environmental Microbiology 58: 2144

Henriksen DB, Rolland M, Jakobsen MH, Buchardt O, Breddam K (1992)
C-terminal amidation of calcitonin by carboxypeptidase Y catalyzed transpeptidation with a photocleavable nucleophile
Pept Res 5: 321

Liao DI, Breddam K, Sweet RM, Bullock T, Remington SJ (1992)
Refined atomic model of wheat serine carboxypeptidase II at 2.2-A resolution
Biochemistry 31: 9796

Wilson KP, Liao DI, Bullock T, Remington SJ, Breddam K (1990)
Crystallization of serine carboxypeptidases
Journal of Molecular Biology 211: 301

Bech LM, Breddam K (1989)
Inactivation of carboxypeptidase Y by mutational removal of the putative essential histidyl residue
Carlsberg Res Commun 54: 165

Sorensen SB, Svendsen I, Breddam K (1989)
Primary structure of carboxypeptidase III from malted barley
Carlsberg Res Commun 54: 193

Bech LM, Breddam K (1988)
Chemical modifications of a cysteinyl residue introduced in the binding site of carboxypeptidase Y by site-directed mutagenesis
Carlsberg Res Commun 53: 381

Sorensen SB, Svensen I, Breddam K (1987)
Primary structure of carboxypeptidase II from malted barley.
Carlsberg Res Commun 52: 285

Sorensen SB, Breddam K, Svensen I (1986)
Primary structure of carboxypeptidase I from malted barley
Carlsberg Res Commun 51: 475