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The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design
Journal of the American Chemical Society 126: 15405
Rydberg EH, Macion R, Zeev-Ben-Mordehai T, Solomon A, Rees DM, Toker L, Botti SA, Auld VJ, Silman I, Sussman JL (2004)
Overexpression of the extracellular and cytoplasmic domains of the Drosophila adhesion protein, gliotactin.
Cholinergic Mechanisms, CRC Press
Sussman JL, Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, Toker L, Botti SA, Auld VJ, Silman I (2004)
Poster (31) Natively unstructured proteins: a case study of cholinesterase-like adhesion molecules (clams)
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 337
Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, Toker L, Auld VJ, Silman I, Botti SA, Sussman JL (2003)
The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded
Proteins 53: 758
Botti SA, Felder CE, Lifson S, Sussman JL, Silman I (1999)
A modular treatment of molecular traffic through the active site of cholinesterase
Biophysical Journal 77: 2430
Botti SA, Felder CE, Sussman JL, Silman I (1998)
Electrotactins: a class of adhesion proteins with conserved electrostatic and structural motifs
Protein Engineering 11: 415
Botti SA, Felder CE, Sussman JL, Silman I (1998)
Electrostatic homology modelling of a set of ChE-like neural adhesion proteins identifies a shared annular motif with ChEs. Structural implications for a cell-recognition role of ChEs
Journal de Physiologie (Paris) 92: 414
Botti SA, Felder CE, Lifson S, Sussman JL, Silman I (1998)
An Integrated Model for the Molecular Traffic through the Active Site of Cholinesterases
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Botti SA, Felder CE, Sussman JL, Silman I (1998)
The Conjunction of a Conserved Electrostatic Motif and a Common Cholinesterase Fold Defines a Class of Adhesion Proteins
In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.: 448
Felder CE, Botti SA, Lifson S, Silman I, Sussman JL (1997)
External and internal electrostatic potentials of cholinesterase models
J Mol Graph Model 15: 318