Gerlits O, Fajer M, Cheng X, Blumenthal DK, Radic Z, Kovalevsky A (2022)
Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering
Structure
Blumenthal DK, Cheng X, Fajer M, Ho KY, Rohrer J, Gerlits O, Taylor P, Juneja P, Kovalevsky A, Radic Z (2021)
Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects
Journal of Biological Chemistry
Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radic Z (2020)
Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
Journal of Biological Chemistry 295: 4079
Gerlits O, Kong X, Cheng X, Wymore T, Blumenthal DK, Taylor P, Radic Z, Kovalevsky A (2019)
Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase
Journal of Biological Chemistry 294: 10607
Kovalevsky A, Blumenthal DK, Cheng X, Taylor P, Radic Z (2016)
Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning
Annals of the New York Academy of Sciences 1378: 41
Terry CM, Carlson ML, He Y, Ulu A, Morisseau C, Blumenthal DK, Hammock BD, Cheung AK (2014)
Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model
J Vasc Res 51: 269